Zobrazeno 1 - 10
of 323
pro vyhledávání: '"TNFalpha"'
Publikováno v:
Physiological Reports, Vol 12, Iss 14, Pp n/a-n/a (2024)
Abstract The monocyte–macrophage system plays an important role in phagocytosis of pathogens and cellular debris following infection or tissue injury in several pathophysiological conditions. We examined ENaC/ASIC subunit transcript expression and
Externí odkaz:
https://doaj.org/article/6bd6768a9abf49ddbbe67da66733ab69
Autor:
Konstantin Dergilev, Ekaterina Zubkova, Alika Guseva, Zoya Tsokolaeva, Yulia Goltseva, Irina Beloglazova, Elizaveta Ratner, Alexander Andreev, Stanislav Partigulov, Mikhail Lepilin, Mikhail Menshikov, Yelena Parfyonova
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 16575 (2023)
Ischemic heart disease and its complications, such as myocardial infarction and heart failure, are the leading causes of death in modern society. The adult heart innately lacks the capacity to regenerate the damaged myocardium after ischemic injury.
Externí odkaz:
https://doaj.org/article/95e1d4e463214edbad70b20689122ee6
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Methotrexate (MTX) is an essential anti-rheumatic drug used to treat rheumatoid arthritis (RA). Prevention or management of adverse reactions, including interstitial lung disease (ILD), hepatotoxicity, myelosuppression, and infection, remains fundame
Externí odkaz:
https://doaj.org/article/1550b575571149a480933cbdfa0dc762
Akademický článek
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Akademický článek
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Akademický článek
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Publikováno v:
Pharmaceutics, Vol 13, Iss 6, p 844 (2021)
The transport of macromolecular drugs such as oligonucleotides into the lungs has become increasingly relevant in recent years due to their high potency. However, the chemical structure of this group of drugs poses a hurdle to their delivery, caused
Externí odkaz:
https://doaj.org/article/f345957e2c0940a69a98cba75f84fe9b
Autor:
Dietrich Trümbach, Susanne Pfeiffer, Manuel Poppe, Hagen Scherb, Sebastian Doll, Wolfgang Wurst, Joel A. Schick
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-13 (2017)
Abstract Background As CRISPR/Cas9 mediated screens with pooled guide libraries in somatic cells become increasingly established, an unmet need for rapid and accurate companion informatics tools has emerged. We have developed a lightweight and effici
Externí odkaz:
https://doaj.org/article/6704917521cc44b4ad335a258ed0bb95
Publikováno v:
ADMET and DMPK, Vol 4, Iss 3, Pp 232-240 (2016)
VCAM-1 cell surface expression was determined by flow cytometry in rat aorta endothelial cells stimulated with insulin and/or Tumor Necrosis Factor-a in the absence or presence of short-hairpin RNA inhibitors of c-Jun N-terminal Kinase (JNK) and p38
Externí odkaz:
https://doaj.org/article/daf2a7e0849d4771a9335f3676c1bccb
Autor:
Sara Taha, Elias Volkmer, Elisabeth Haas, Paolo Alberton, Tobias Straub, Diana David-Rus, Attila Aszodi, Riccardo Giunta, Maximilian Michael Saller
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 1086 (2020)
The application of liposuctioned white adipose tissue (L-WAT) and adipose-derived stem cells (ADSCs) as a novel immunomodulatory treatment option is the currently subject of various clinical trials. Because it is crucial to understand the underlying
Externí odkaz:
https://doaj.org/article/6e23e3d9289b48f5b99060de70db49b9