Zobrazeno 1 - 10
of 1 659
pro vyhledávání: '"TNF inhibitor"'
Autor:
Roy Fleischmann, Ricardo Blanco, Filip Van den Bosch, Louis Bessette, Yanna Song, Sara K. Penn, Erin McDearmon-Blondell, Nasser Khan, Kelly Chan, Eduardo Mysler
Publikováno v:
Rheumatology and Therapy, Vol 11, Iss 3, Pp 599-615 (2024)
Abstract Introduction This study aimed to describe the long-term efficacy and safety of upadacitinib and adalimumab through 228 weeks following immediate switch to the alternate therapy with a different mechanism of action (MoA) in patients with rheu
Externí odkaz:
https://doaj.org/article/bda276920acf4632bf961e69f50d248a
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionLoss of NADPH oxidase activity results in proinflammatory macrophages that contribute to hyperinflammation in Chronic Granulomatous Disease (CGD). Previously, it was shown in a zymosan-induced peritonitis model that gp91phox-/- (CGD) mono
Externí odkaz:
https://doaj.org/article/73d155270d1d405cb161babfaf07b083
Autor:
T. V. Tyrinova, A. Yu. Morenkova, A. V. Fedorova, M. A. Tikhonova, N. A. Ilina, O. A. Chumasova, A. E. Sizikov
Publikováno v:
Медицинская иммунология, Vol 25, Iss 5, Pp 1079-1084 (2023)
Innate immune cells, including myeloid cells — myeloid derived suppressor cells (MDSCs) — are supposed to play an important role in the pathogenesis of axial spondyloarthritis (AxSp). Myeloid derived suppressor cells represent a heterogeneous pop
Externí odkaz:
https://doaj.org/article/f5b07d99d2e24aaba740d85a74112fe0
Autor:
Jacqueline D. Squire, Claudia R. Libertin, Harry Powers, Jared Nelson, Lisa Brumble, Federico R. Laham, Anahita Agharahimi, Alexandra F. Freeman, Jennifer W. Leiding
Publikováno v:
International Journal of Infectious Diseases, Vol 131, Iss , Pp 162-165 (2023)
Tumor necrosis factor-a inhibitors can be associated with increased risk of infections, particularly reactivation of latent tuberculosis or nontuberculous mycobacterium (NTM). However, because disseminated NTM is rare, inborn errors of immunity shoul
Externí odkaz:
https://doaj.org/article/1ba96126cd5e406eb3005c4a6ba4db0a
Publikováno v:
Journal of Dermatological Treatment, Vol 34, Iss 1 (2023)
Tumor necrosis factor (TNF) inhibitors improved clinical outcomes for patients with psoriasis but are limited by their high cost. There are several biosimilar options approved for the treatment of psoriasis which provides a lower-cost alternative and
Externí odkaz:
https://doaj.org/article/e6a63621b2cd4e6cb7b14e1a6e76c824
Autor:
Yan Li, Zhengyuan Hu, Yufei Guo, Zheng Zhao, Kunpeng Li, Xiuru Wang, Jie Zhang, Dongfeng Liang, Jianglin Zhang, Xiaoyue Hu, Jian Zhu, Feng Huang
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Objectives: The impact of non-steroidal anti-inflammatory drugs (NSAIDs), conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) and tumor necrosis factor inhibitors (TNFi) on the outcomes of mild-moderate COVID-19 in patients with a
Externí odkaz:
https://doaj.org/article/721d5e0cd4e442d39f5ebc8f7157eb8a
Autor:
Vivian Oliveira Nunes Teixeira, Bárbara Jonson Bartikoski, Rafaela Cavalheiro do Espirito Santo, Paulo Vinícius Gil Alabarse, Khetam Ghannan, Jordana Miranda Souza Silva, Lidiane Isabel Filippin, Fernanda Visioli, Lorena Martinez-Gamboa, Eugen Feist, Ricardo Machado Xavier
Publikováno v:
Advances in Rheumatology, Vol 63, Iss 1, Pp 1-12 (2023)
Abstract Background Rheumatoid arthritis is an autoimmune inflammatory disease that often leads patients to muscle impairment and physical disability. This study aimed to evaluate changes in the activity of proteasome system in skeletal muscles of mi
Externí odkaz:
https://doaj.org/article/eb8e31c54a134de4a87ffe6ab567c7f9
Autor:
Daniel Sobral, Ana Filipa Fernandes, Miguel Bernardes, Patrícia Pinto, Helena Santos, João Lagoas-Gomes, José Tavares-Costa, José A. P. Silva, João Madruga Dias, Alexandra Bernardo, Jean-Charles Gaillard, Jean Armengaud, Vladimir Benes, Lúcia Domingues, Sara Maia, Jaime C. Branco, Ana Varela Coelho, Fernando M. Pimentel-Santos
Publikováno v:
Biomolecules, Vol 14, Iss 3, p 382 (2024)
This study aims at identifying molecular biomarkers differentiating responders and non-responders to treatment with Tumor Necrosis Factor inhibitors (TNFi) among patients with axial spondyloarthritis (axSpA). Whole blood mRNA and plasma proteins were
Externí odkaz:
https://doaj.org/article/1ce5cc21929546879b104f7e022fd28b
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 16, Pp 2755-2765 (2022)
He-xiang Zong, Sheng-qian Xu, Jian-xiong Wang, Yi-ran Chu, Ke-ming Chen, Cong Wang, Wan-qiu Tong, Xi-le Wang Department of Rheumatology and Immunology, The First Affiliated Hospital of Anhui Medical University, Hefei, People’s Republic of ChinaCorr
Externí odkaz:
https://doaj.org/article/86396ae00f774c02acf56f3ec4327aab
Autor:
G. V. Santalova, S. V. Plakhotnikova
Publikováno v:
Медицинский совет, Vol 0, Iss 12, Pp 173-177 (2022)
The article presents a clinical case of systemic juvenile idiopathic arthritis that began after a spinal injury in a 9-year-old child. The authors noted the importance of dysregulation of the innate immune system in the pathogenesis of systemic juven
Externí odkaz:
https://doaj.org/article/a462afcfedb54fb9a0e839b1f03f82d7