Zobrazeno 1 - 10
of 130
pro vyhledávání: '"TNFα, Tumor Necrosis Factor α"'
Autor:
Rohit A. Panchakshari, Athanasia Apostolou, Cosmas Giallourakis, Galeb Abu-Ali, Antara Banerjee, Tengku Ibrahim Maulana, Raymond Luc, Gauri Kulkarni, Carolina Lucchesi, Jordan Kerns, Katia Karalis, Alexandra Dimitriou, Maria D. Paraskevopoulou, Magdalena Kasendra, Elias S. Manolakos, Lorna Ewart, Geraldine A. Hamilton, Bertram Bleck, Dimitris V. Manatakis
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1719-1741 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1719-1741 (2021)
Background & Aims The limited availability of organoid systems that mimic the molecular signatures and architecture of human intestinal epithelium has been an impediment to allowing them to be harnessed for the development of therapeutics as well as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c73f86b030301637ffe301dbedd59d97
http://europepmc.org/articles/PMC8551844
http://europepmc.org/articles/PMC8551844
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 7, Pp 12119-12134 (2014)
Tumor necrosis factor (TNF)-α is elevated during the acute phase of Kawasaki disease (KD), which damages vascular endothelial cells to cause systemic vasculitis. In the current study, we investigated the potential role of cordycepin on TNFα express
Externí odkaz:
https://doaj.org/article/14e73416da16474fb7e630cd43f52646
Publikováno v:
Genes and Diseases, Vol 8, Iss 2, Pp 117-123 (2021)
Genes & Diseases
Genes & Diseases
Breast cancer is the second highest prevalent cancer globally after lung cancer with 2.09 million cases during 2018. Adults about 1.9 billion were overweight and over 650 million out of these were obese during 2016. There is a significant relationshi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac3b6d350d2765a112ecc8a00cead5d6
https://doi.org/10.1016/j.gendis.2019.09.006
https://doi.org/10.1016/j.gendis.2019.09.006
Autor:
Ali Shahbazi, Ali Sepehrinezhad, Fin Stolze Larsen, Mohammad Taghi Joghataei, Sajad Sahab Negah
Publikováno v:
Toxicology Reports, Vol 8, Iss, Pp 962-970 (2021)
Toxicology Reports
Toxicology Reports
Highlights • To figure out the pathogenesis of HE, the improvement of the animal model is warranted. • TAA has been introduced as a valid model because it mimics many pathological features of patients with ALF and HE. • TAA as a chemical agent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14dbc46c8dde15de693657f6b641b623
http://www.sciencedirect.com/science/article/pii/S2214750021000871
http://www.sciencedirect.com/science/article/pii/S2214750021000871
Autor:
Bruce D. Hammock, A. F. S. Mello, Natalie J. Török, Fawaz G. Haj, Jun Yang, Ming-Fo Hsu, Bryan Chu, Christophe Morisseau, Jeff Cheng, Shinichiro Koike
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 3, Pp 815-830 (2021)
Cellular and molecular gastroenterology and hepatology, vol 11, iss 3
Cellular and Molecular Gastroenterology and Hepatology
Cellular and molecular gastroenterology and hepatology, vol 11, iss 3
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Alcohol-associated liver disease (ALD) is a significant cause of liver-related morbidity and mortality worldwide and with limited therapies. Soluble epoxide hydrolase (sEH; Ephx2) is a largely cytosolic enzyme that is highly express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a37aec2ab2970ef64d585a65ffea8d3
http://www.sciencedirect.com/science/article/pii/S2352345X20301624
http://www.sciencedirect.com/science/article/pii/S2352345X20301624
Autor:
Johannes Seeger, Marie Mewes, Sophie Sigusch, Aida Salameh, Ingo Dähnert, Marcel Vollroth, Stefan Dhein, Philipp Kiefer
Publikováno v:
Saudi Journal of Biological Sciences, Vol 27, Iss 1, Pp 18-29 (2020)
Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences
Severe inborn cardiac malformations are typically corrected in cardioplegia, with a cardio-pulmonary bypass (CPB) taking over body circulation. During the operation the arrested hearts are subjected to a global ischemia/reperfusion injury. Although t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d5365bb8c01902b28b5ec20940c25b5
https://doi.org/10.1016/j.sjbs.2019.04.003
https://doi.org/10.1016/j.sjbs.2019.04.003
Autor:
Ernest G. Seidman, Megan E. Himmel, May Q. Wong, Megan K. Levings, Daniel J. Lisko, Brian Bressler, Laura Cook, Rosa Garcia, Theodore S. Steiner
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 3, Pp 485-506 (2020)
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 3, Pp 485-506 (2020)
Background & Aims Bacterial flagellin is an important antigen in inflammatory bowel disease, but the role of flagellin-specific CD4+ T cells in disease pathogenesis remains unclear. Also unknown is how changes in intestinal microbiome intersect with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b30d89a7366b60f27ecba6f53e0ece9a
https://doi.org/10.1016/j.jcmgh.2019.11.012
https://doi.org/10.1016/j.jcmgh.2019.11.012
Autor:
Mary Rezk‐Hanna, Daniel Dobrin, Jesus A. Araujo, Angelica Means, Charlie O. Nettle, Mary Lynn-Brecht, Donald P. Tashkin, Chiao-Wei Cheng, Rajat Gupta
Publikováno v:
Chest, vol 161, iss 1
Chest
Chest
Background Traditional hookah smoking has grown quickly to become a global tobacco epidemic. More recently, electronic hookahs (e-hookahs)—vaped through traditional water pipes—were introduced as healthier alternatives to combustible hookah. With
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b7fe8f1ba7ff11bea592c92b7bc5a34
https://escholarship.org/uc/item/7xr1c65b
https://escholarship.org/uc/item/7xr1c65b
Autor:
Justine Gillard, Laure-Alix Clerbaux, Bart Staels, Anne Tailleux, Isabelle Leclercq, Laure B. Bindels, Maxime Nachit, Christine Sempoux
Publikováno v:
JHEP reports, vol. 4, no. 1, pp. 100387
JHEP Reports, Vol 4, Iss 1, Pp 100387-(2022)
JHEP reports, Vol. 4, no.1, p. 100387 [1-13] (2022)
JHEP Reports
JHEP Reports, Vol 4, Iss 1, Pp 100387-(2022)
JHEP reports, Vol. 4, no.1, p. 100387 [1-13] (2022)
JHEP Reports
Background & Aims Through FXR and TGR5 signaling, bile acids (BAs) modulate lipid and glucose metabolism, inflammation and fibrosis. Hence, BAs returning to the liver after enteric secretion, modification and reabsorption may contribute to the pathog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f803f3cd8976e73d533d8b1885ead5
https://serval.unil.ch/notice/serval:BIB_8BED7E41CA16
https://serval.unil.ch/notice/serval:BIB_8BED7E41CA16
Autor:
Mingqiao Li, Weihua Wang, Ying Cheng, Xiaoxun Zhang, Nan Zhao, Ya Tan, Qiaoling Xie, Jin Chai, Qiong Pan
Publikováno v:
The Journal of Biological Chemistry
Cholestasis is a common condition in which the flow of bile from the liver to the intestines is inhibited. It has been shown that organic anion–transporting polypeptide 3A1 (OATP3A1) is upregulated in cholestasis to promote bile acid efflux transpo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87568537078818c628c5dc973f5fcc6f
https://pubmed.ncbi.nlm.nih.gov/34971708
https://pubmed.ncbi.nlm.nih.gov/34971708