Zobrazeno 1 - 10
of 94
pro vyhledávání: '"TMZ, temozolomide"'
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Glioblastoma (GBM) is the most common primary brain tumor, carrying a very poor prognosis, with median overall survival at about 12 to 15 months despite surgical resection, chemotherapy with temozolomide (TMZ), and radiation therapy. GBM recurs in th
Externí odkaz:
https://doaj.org/article/7d14a9f214384681b54a778cf4f88157
Publikováno v:
World Journal of Advanced Research and Reviews. 16:884-892
Both carbazole and thiosemicarbazide scaffold showed various potential biological activities in medicinal chemistry. In this research work, we synthesized a series of carbazole bearing thiosemicarbazide derivatives (17-28) and evaluated thierin vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41eaf2584c60946eb3d227cad4f5858b
https://doi.org/10.30574/wjarr.2022.16.3.1402
https://doi.org/10.30574/wjarr.2022.16.3.1402
Autor:
Gong, Ke, Guo, Gao, Beckley, Nicole, Zhang, Yue, Yang, Xiaoyao, Sharma, Mishu, Habib, Amyn A.
Publikováno v:
Neoplasia (New York, N.Y.)
Tumor necrosis factor (TNF) and its receptors are widely expressed in non-small cell lung cancer (NSCLC). TNF has an established role in inflammation and also plays a key role in inflammation-induced cancer. TNF can induce cell death in cancer cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4e8b516daf685f177d5f7b56fbeccc0e
http://europepmc.org/articles/PMC7773536
http://europepmc.org/articles/PMC7773536
Autor:
Marie D. Ralff, Benedito A. Carneiro, Lanlan Zhou, Wen-I Chang, Rohinton Tarapore, Varun V. Prabhu, Joshua N. Honeyman, Attila A. Seyhan, Isacco Ferrarini, Alexander G. Raufi, Lindsey Carlsen, Martin Stogniew, Lee Schalop, Robyn Borsuk, Joshua E. Allen, Aakash Jhaveri, Cassandra Parker, Sara Morrow, Young Lee, Fabio Tavora, Wolfgang Oster, Jocelyn E. Ray, Kelsey E. Huntington, Howard Safran, Anna D Louie, Abed Rahman Kawakibi, Yiqun Zhang, Wafik S. El-Deiry
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 12, Pp 725-744 (2020)
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 12, Pp 725-744 (2020)
ONC201 was originally discovered as TNF-Related Apoptosis Inducing Ligand (TRAIL)-inducing compound TIC10. ONC201 appears to act as a selective antagonist of the G protein coupled receptor (GPCR) dopamine receptor D2 (DRD2), and as an allosteric agon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::788cb5d6703ffa407652b681a16c6c03
http://europepmc.org/articles/PMC7588802
http://europepmc.org/articles/PMC7588802
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 2, Pp 239-248 (2020)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Nowadays, nanotechnology is revolutionizing the approaches to different fields from manufacture to health. Carbon nanotubes (CNTs) as promising candidates in nanomedicine have great potentials in developing novel entities for central nervous system p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::733fff34f30ef2de86219e20aec8517f
http://www.sciencedirect.com/science/article/pii/S2211383519306069
http://www.sciencedirect.com/science/article/pii/S2211383519306069
Autor:
Rakesh Mishra, Abdul Quaiyoom Khan, Rehan Khan, Anas Ahmad, Muneeb U. Rehman, Akshay Vyawahare, Ashok Kumar, Wajhul Qamar
Publikováno v:
Saudi Pharmaceutical Journal, Vol 27, Iss 8, Pp 1113-1126 (2019)
Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal : SPJ
Graphical abstract
Cancer remains the topmost disorders of the mankind and number of cases is unceasingly growing at unprecedented rates. Although the synthetic anti-cancer compounds still hold the largest market in the modern treatment of cance
Cancer remains the topmost disorders of the mankind and number of cases is unceasingly growing at unprecedented rates. Although the synthetic anti-cancer compounds still hold the largest market in the modern treatment of cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83c3f982c7088407eff18e6c8b9dcfe0
http://www.sciencedirect.com/science/article/pii/S1319016419301227
http://www.sciencedirect.com/science/article/pii/S1319016419301227
Publikováno v:
Journal of neurosurgery. Case lessons, vol 2, iss 1
BackgroundProviding the standard of care to patients with glioblastoma (GBM) during the novel coronavirus of 2019 (COVID-19) pandemic is a challenge, particularly if a patient tests positive for severe acute respiratory syndrome coronavirus 2 (SARS-C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::66ab32f5e53e152f0ad4944a618c9057
https://escholarship.org/uc/item/7mw601dv
https://escholarship.org/uc/item/7mw601dv
Autor:
Jinquan Cai, Ruijia Wang, Lin Lin, Hengyuan Pang, Magafurov Dinislam, Ziwei Li, Shihong Zhao, Qun Chen, Chuanlu Jiang, Pengfei Wu, Caijun Zha, Chunbin Duan, Xiangqi Meng, Bo Han
Publikováno v:
EBioMedicine
Background DNA damage repair (DDR) alterations are important events in cancer initiation, progression, and therapeutic resistance. However, the involvement of DDR alterations in glioma malignancy needs further investigation. This study aims to charac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae288d30336e455721de6bf5436f314b
https://doi.org/10.1016/j.ebiom.2019.01.067
https://doi.org/10.1016/j.ebiom.2019.01.067
Autor:
David L. Perrin, Ehsan Samiei, Mohammad Esmaeillou, Arya Emami, Saeid Ghavami, Mohsen Akbari, Joseph W. Gordon, Kiarash Roustai Geraylow, Mahboubeh Kavoosi, Evan Stefanek, Milad Ashrafizadeh
Publikováno v:
MethodsX, Vol 8, Iss, Pp 101473-(2021)
MethodsX
MethodsX
Rhabdomyosarcoma (RMS) is the most common pediatric soft-tissue malignant tumor. Treatment of RMS usually includes primary tumor resection along with systemic chemotherapy. Two-dimensional (2D) cell culture systems and animal models have been extensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a65b5f28456d93429faadea2d4109e
http://www.sciencedirect.com/science/article/pii/S2215016121002661
http://www.sciencedirect.com/science/article/pii/S2215016121002661
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 10 (2020)
Frontiers in Oncology, Vol 10 (2020)
Glioblastoma (GBM) is the most common primary brain tumor, carrying a very poor prognosis, with median overall survival at about 12 to 15 months despite surgical resection, chemotherapy with temozolomide (TMZ), and radiation therapy. GBM recurs in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c666c878e3b43a92586b42919d2c793