Zobrazeno 1 - 10
of 2 452
pro vyhledávání: '"TMEM127"'
Autor:
Timothy J Walker, Eduardo Reyes-Alvarez, Brandy D Hyndman, Michael G Sugiyama, Larissa CB Oliveira, Aisha N Rekab, Mathieu JF Crupi, Rebecca Cabral-Dias, Qianjin Guo, Patricia LM Dahia, Douglas S Richardson, Costin N Antonescu, Lois M Mulligan
Publikováno v:
eLife, Vol 12 (2024)
Internalization from the cell membrane and endosomal trafficking of receptor tyrosine kinases (RTKs) are important regulators of signaling in normal cells that can frequently be disrupted in cancer. The adrenal tumor pheochromocytoma (PCC) can be cau
Externí odkaz:
https://doaj.org/article/56671c5952a34e068944e75893122071
Akademický článek
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Autor:
Guo, Qianjin, Cheng, Zi-Ming, Gonzalez-Cantú, Hector, Rotondi, Matthew, Huelgas-Morales, Gabriela, Ethiraj, Purushoth, Qiu, Zhijun, Lefkowitz, Jonathan, Song, Wan, Landry, Bethany N., Lopez, Hector, Estrada-Zuniga, Cynthia M., Goyal, Shivi, Khan, Mohammad Aasif, Walker, Timothy J., Wang, Exing, Li, Faqian, Ding, Yanli, Mulligan, Lois M., Aguiar, Ricardo C.T., Dahia, Patricia L.M.
Publikováno v:
In Cell Reports 26 September 2023 42(9)
Autor:
Delgado JF; Facultad de Medicina, Complejo Asistencial Dr. Sótero del Río, Santiago, Chile., Pérez E MJ; Facultad de Medicina, Complejo Asistencial Dr. Sótero del Río, Santiago, Chile., Delgado D; Lassiter High School, Chile., Lagos C; Escuela de Química y Farmacia, Facultad de Medicina y Ciencia, Universidad San Sebastián, Chile., Baudrand R; Departamento de Endocrinología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile., Uslar T; Departamento de Endocrinología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Publikováno v:
Revista medica de Chile [Rev Med Chil] 2022 Aug; Vol. 150 (8), pp. 1115-1118.
Autor:
M. Yu. Yukina, V. R. Mustafina, E. V. Vasilyev, E. A. Troshina, N. M. Platonova, D. G. Beltsevich
Publikováno v:
Медицинский совет, Vol 0, Iss 7, Pp 150-154 (2021)
Pheochromocytoma/paraganglioma is a neuroendocrine tumor of chromaffin and nonchromaffin cells of the autonomic nervous system, in most cases localized in the medullary layer of the adrenal gland. Its development is often associated with genetic pred
Externí odkaz:
https://doaj.org/article/64d9aa005006432183cb570b2bee2f6c
Autor:
Walker TJ; Division of Cancer Biology and Genetics, Cancer Research Institute, and Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, K7L 3N6, Canada., Reyes-Alvarez E; Division of Cancer Biology and Genetics, Cancer Research Institute, and Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, K7L 3N6, Canada., Hyndman BD; Division of Cancer Biology and Genetics, Cancer Research Institute, and Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, K7L 3N6, Canada., Sugiyama MG; Department of Chemistry and Biology, Toronto Metropolitan University, Toronto, ON, M5B 2K3, Canada., Oliveira LCB; Division of Cancer Biology and Genetics, Cancer Research Institute, and Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, K7L 3N6, Canada., Rekab AN; Division of Cancer Biology and Genetics, Cancer Research Institute, and Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, K7L 3N6, Canada., Crupi MJF; Division of Cancer Biology and Genetics, Cancer Research Institute, and Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, K7L 3N6, Canada., Cabral-Dias R; Department of Chemistry and Biology, Toronto Metropolitan University, Toronto, ON, M5B 2K3, Canada., Guo Q; Division of Hematology and Medical Oncology, University of Texas Health Science Center, San Antonio, Texas, 78229, United States., Dahia PLM; Division of Hematology and Medical Oncology, University of Texas Health Science Center, San Antonio, Texas, 78229, United States., Richardson DS; Department of Molecular and Cellular Biology; Harvard Center for Biological Imaging; Scientific Image Analysis Group, Harvard University, Cambridge, MA, USA., Antonescu CN; Department of Chemistry and Biology, Toronto Metropolitan University, Toronto, ON, M5B 2K3, Canada., Mulligan LM; Division of Cancer Biology and Genetics, Cancer Research Institute, and Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, K7L 3N6, Canada.
Publikováno v:
BioRxiv : the preprint server for biology [bioRxiv] 2024 Apr 03. Date of Electronic Publication: 2024 Apr 03.
Autor:
Qianjin Guo, Zi-Ming Cheng, Hector Gonzalez-Cantú, Matthew Rotondi, Gabriela Huelgas-Morales, Purushoth Ethiraj, Zhijun Qiu, Jonathan Lefkowitz, Wan Song, Bethany N. Landry, Hector Lopez, Cynthia M. Estrada-Zuniga, Shivi Goyal, Mohammad Aasif Khan, Timothy J. Walker, Exing Wang, Faqian Li, Yanli Ding, Lois M. Mulligan, Ricardo C.T. Aguiar, Patricia L.M. Dahia
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113070- (2023)
Summary: The TMEM127 gene encodes a transmembrane protein of poorly known function that is mutated in pheochromocytomas, neural crest-derived tumors of adrenomedullary cells. Here, we report that, at single-nucleus resolution, TMEM127-mutant tumors s
Externí odkaz:
https://doaj.org/article/74efd737d1554c5e84e35c4daa5fe892
Publikováno v:
Discover Oncology, Vol 13, Iss 1, Pp 1-8 (2022)
Highlights Survival rates remain very low in patients with osteosarcoma (OS). Identification of new diagnostic biomarkers and therapeutic targets is essential. miR-23b-5p was transfected into OS cells to study the biological effects. miR-23b-5p promo
Externí odkaz:
https://doaj.org/article/0c7662a2b8764c818ae67144c26dd825
Autor:
Alix, Eric, Godlee, Camilla, Cerny, Ondrej, Blundell, Samkeliso, Tocci, Romina, Matthews, Sophie, Liu, Mei, Pruneda, Jonathan N., Swatek, Kirby N., Komander, David, Sleap, Tabitha, Holden, David W.
Publikováno v:
In Cell Host & Microbe 8 July 2020 28(1):54-68
Autor:
Fernández-Pombo, Antía1,2, Cameselle-Teijeiro, José M.3, Puñal-Rodríguez, Jose A.4, Loidi, Lourdes5, Peinó-García, Roberto1, Cabanas-Rodríguez, Paloma6, Garrido-Pumar, Miguel7, Baleato-González, Sandra8, Flores-Ríos, Enrique8, Araújo-Vilar, David1,2
Publikováno v:
Case Reports in Endocrinology. 10/27/2019, p1-5. 5p.