Zobrazeno 1 - 10
of 11
pro vyhledávání: '"TME, tumour microenvironment"'
Autor:
Kenji Izumi, Nyein Nyein Chan, Jun-ichi Tanuma, Satoshi Maruyama, Kenta Haga, Masami Kawaharada, Manabu Yamazaki, Ayako Suzuki, Toshihiko Mikami, Tadaharu Kobayashi, Emi Hoshikawa, Akinori Funayama
Publikováno v:
Translational Oncology, Vol 14, Iss 12, Pp 101236-(2021)
Translational Oncology
Translational Oncology
Highlights • TGF-β1 secreted from CAFs promote the migration and invasion of OSCC cells. • CAFs upregulate SOX9 expression of OSCC cells, possibly through inducing EMT. • The presence of CAFs is correlated with SOX9 expression in the invasive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f37e513d06f9e4f0bfec369f2e664e8f
http://www.sciencedirect.com/science/article/pii/S193652332100228X
http://www.sciencedirect.com/science/article/pii/S193652332100228X
Autor:
Orla Prendiville, Noel E Donlon, Cara Dunne, Croí E. Buckley, Helen P. Berrigan, Timothy Nugent, Lorraine Brennan, J. O. Larkin, Michael Durand, Niamh Lynam-Lennon, Heleena Moni Bottu, Amy M. Buckley, Aisling B Heeran, Brian Mehigan, Jacintha O'Sullivan, Niamh Clarke, Paul McCormick
Publikováno v:
Translational Oncology
Translational Oncology, Vol 14, Iss 1, Pp 100882-(2021)
Translational Oncology, Vol 14, Iss 1, Pp 100882-(2021)
Locally advanced rectal cancer is treated with neoadjuvant-chemoradiotherapy, however only 22% of patients achieve a complete response. Resistance mechanisms are poorly understood. Radiation-induced Bystander Effect (RIBE) describes the effect of rad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c7b36a639368d9167dde0b2fddde74d
http://europepmc.org/articles/PMC7586242
http://europepmc.org/articles/PMC7586242
Publikováno v:
EBioMedicine, Vol 59, Iss, Pp 102975-(2020)
EBioMedicine
Elsevier
EBioMedicine
Elsevier
© 2020 The Author(s) Natural Killer (NK) cells and CD8+ cytotoxic T cells are two types of immune cells that can kill target cells through similar cytotoxic mechanisms. With the remarkable success of chimeric antigen receptor (CAR)-engineered T (CAR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::849da866226738d910b3a40ed87727a6
http://www.sciencedirect.com/science/article/pii/S2352396420303510
http://www.sciencedirect.com/science/article/pii/S2352396420303510
Publikováno v:
Seminars in Immunology
Neutrophils are essential soldiers of the immune response and their role have long been restricted to their activities in defence against microbial infections and during the acute phase of the inflammatory response. However, increasing number of inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::882a51ed710827cb924f515c092a4514
https://pubmed.ncbi.nlm.nih.gov/32958359
https://pubmed.ncbi.nlm.nih.gov/32958359
Autor:
Jia-Tao Zhang, Jian Su, Hai-Yan Tu, Hao Sun, Xu-Chao Zhang, Zhi-Hong Chen, Jin-Ji Yang, Qing Zhou, Yi-Long Wu, Jia-Ying Zhou, Si-Yang Maggie Liu, Kai Yin
Publikováno v:
Translational Oncology
Translational Oncology, Vol 15, Iss 1, Pp 101254-(2022)
Translational Oncology, Vol 15, Iss 1, Pp 101254-(2022)
Highlights • Predictive power of PD response for ICIs was superior than traditional biomarkers; • Predictive efficacy was improved by integrating tumor-immune-related features; • When tumor-specific feature was replaced, the model has pan-cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daad381fb5c7640d53e71e4388f09e65
https://doi.org/10.1016/j.tranon.2021.101254
https://doi.org/10.1016/j.tranon.2021.101254
Autor:
Matías A. Avila, María Arechederra, Leticia Colyn, Maite G. Fernandez-Barrena, Carmen Berasain
Publikováno v:
JHEP Reports
Summary Hepatocellular carcinoma (HCC) is a deadly tumour whose causative agents are generally well known, but whose pathogenesis remains poorly understood. Nevertheless, key genetic alterations are emerging from a heterogeneous molecular landscape,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd34b06289cc41bef258ab67c7a43231
https://doi.org/10.1016/j.jhepr.2020.100167
https://doi.org/10.1016/j.jhepr.2020.100167
Autor:
Jason, Bennett, Daria, Capece, Federica, Begalli, Daniela, Verzella, Daniel, D'Andrea, Laura, Tornatore, Guido, Franzoso
Publikováno v:
The International Journal of Biochemistry & Cell Biology
Highlights • NF-κB transcription factors are central coordinating regulators of immunity, inflammation and cell survival. • NF-κB pathway is aberrantly and stably activated in cancer. • The ubiquitous presence and pleiotropic physiological ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d0d7f1a39726828047ace038bdd26f18
http://hdl.handle.net/10044/1/55697
http://hdl.handle.net/10044/1/55697
Autor:
Yang H; Medical Oncology, Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea., Kang B; Medical Oncology, Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea.; Yonsei Graduate School, Yonsei University College of Medicine, Seoul, Republic of Korea., Ha Y; Department of Gastroenterology, CHA Bundang Medical Center, Seongnam, Republic of Korea., Lee SH; Department of Surgery, CHA Bundang Medical Center, Seongnam, Republic of Korea., Kim I; Division of Oncology, Department of Internal Medicine, Inje University College of Medicine, Haeundae Paik Hospital, Busan, Republic of Korea., Kim H; Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Republic of Korea., Lee WS; Medical Oncology, Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea., Kim G; Department of Pathology, CHA Bundang Medical Center, Seongnam, Republic of Korea., Jung S; Department of Radiology, CHA Bundang Medical Center, Seongnam, Republic of Korea., Rha SY; Yonsei Graduate School, Yonsei University College of Medicine, Seoul, Republic of Korea.; Division of Medical Oncology, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea., Gaillard VE; F. Hoffmann-La Roche Ltd., Basel, Switzerland., Cheon J; Medical Oncology, Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea., Kim C; Medical Oncology, Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea., Chon HJ; Medical Oncology, Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea.
Publikováno v:
JHEP reports : innovation in hepatology [JHEP Rep] 2023 Jan 16; Vol. 5 (4), pp. 100672. Date of Electronic Publication: 2023 Jan 16 (Print Publication: 2023).
Autor:
Bakkalci D; UCL Centre for 3D Models of Health and Disease, Division of Surgery and Interventional Science, University College London, Charles Bell House, 43-45 Foley Street, W1W 7TS London, UK., Zubir AZA; Unit of Oral and Maxillofacial Pathology, School of Clinical Dentistry, University of Sheffield, 19 Claremont Crescent, S10 2TA Sheffield, UK., Khurram SA; Unit of Oral and Maxillofacial Pathology, School of Clinical Dentistry, University of Sheffield, 19 Claremont Crescent, S10 2TA Sheffield, UK., Pape J; UCL Centre for 3D Models of Health and Disease, Division of Surgery and Interventional Science, University College London, Charles Bell House, 43-45 Foley Street, W1W 7TS London, UK., Heikinheimo K; Department of Oral and Maxillofacial Surgery, Institute of Dentistry, University of Turku and Turku University Hospital, Turku, Finland., Fedele S; Eastman Dental Institute, University College London, London, UK., Cheema U; UCL Centre for 3D Models of Health and Disease, Division of Surgery and Interventional Science, University College London, Charles Bell House, 43-45 Foley Street, W1W 7TS London, UK.
Publikováno v:
Matrix biology plus [Matrix Biol Plus] 2022 Nov 21; Vol. 16, pp. 100125. Date of Electronic Publication: 2022 Nov 21 (Print Publication: 2022).
Autor:
Du Z; Department of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong, PR China., Wang Y; Department of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong, PR China., Liang J; School of Life Sciences, Sun Yat-sen University, No. 135 Xingangxi Road, Guangzhou 510275, PR China., Gao S; Department of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong, PR China., Cai X; Department of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong, PR China., Yu Y; Department of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong, PR China., Qi Z; Department of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong, PR China., Li J; Department of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong, PR China., Xie Y; Precision Medicine Institute, The First Affiliated Hospital, Sun Yat-sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong, PR China., Wang Z; Department of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong, PR China.
Publikováno v:
Computational and structural biotechnology journal [Comput Struct Biotechnol J] 2022 Sep 09; Vol. 20, pp. 5203-5217. Date of Electronic Publication: 2022 Sep 09 (Print Publication: 2022).