Zobrazeno 1 - 10
of 62
pro vyhledávání: '"TMA, tissue microarray"'
Autor:
Kairbaan Hodivala-Dilke, Melania Capasso, Frances R. Balkwill, Hemant M. Kocher, Michele Bombardieri, Sarah Spear, Francesca R. Delvecchio, Andrew Clear, Rachel Elizabeth Ann Fincham, Marina Roy-Luzarraga, John G. Gribben
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology 12(5), 1543-1565 (2021). doi:10.1016/j.jcmgh.2021.06.023
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1543-1565 (2021)
Cellular and Molecular Gastroenterology and Hepatology 12(5), 1543-1565 (2021). doi:10.1016/j.jcmgh.2021.06.023
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1543-1565 (2021)
Background and aims The presence of tertiary lymphoid structures (TLSs) may confer survival benefit to patients with pancreatic ductal adenocarcinoma (PDAC), in an otherwise immunologically inert malignancy. Yet, the precise role in PDAC has not been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbca100680dfb1efb8c0cbafa14981d0
http://europepmc.org/articles/PMC8529396
http://europepmc.org/articles/PMC8529396
Autor:
Jitender Monga, Indra Adrianto, Craig Rogers, Shirish Gadgeel, Dhananjay Chitale, Joshi J. Alumkal, Himisha Beltran, Amina Zoubeidi, Jagadananda Ghosh
Publikováno v:
The Journal of Biological Chemistry
Enzalutamide, a second-generation antiandrogen, is commonly prescribed for the therapy of advanced prostate cancer, but enzalutamide-resistant, lethal, or incurable disease invariably develops. To understand the molecular mechanism(s) behind enzaluta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a8bb1662a1499b7161cd3cc524395ab
http://europepmc.org/articles/PMC8800106
http://europepmc.org/articles/PMC8800106
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 10, Pp 1015-1035 (2019)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
Breast cancer is a heterogeneous disease comprising the estrogen receptor (ER)–positive luminal subtype which is subdivided into luminal A and luminal B and ER-negative breast cancer which includes the triple-negative subtype. This study has four a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::542355ea565d70c766ba7599ccc806ab
http://www.sciencedirect.com/science/article/pii/S1476558619301575
http://www.sciencedirect.com/science/article/pii/S1476558619301575
Autor:
Zengli Liu, Tianli Chen, Rongqi Sun, Yunfei Xu, Bo Qiu, Xiaoming Zhang, Zongli Zhang, Zhipeng Li
Publikováno v:
EBioMedicine
Cholangiocarcinoma (CCA), consisting of intrahepatic (IHCCA), perihilar (PHCCA), and distal (DCCA) CCA, is a type of highly aggressive malignancy with a very dismal prognosis. Potential biomarkers and drug targets of CCA are urgently needed. As a new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e197fc59784ace42f6b472c341de4635
https://doi.org/10.1016/j.ebiom.2019.08.062
https://doi.org/10.1016/j.ebiom.2019.08.062
Autor:
Minner, Sarah, Hager, Dominik, Steurer, Stefan, Höflmayer, Doris, Tsourlakis, Maria Christina, Möller-Koop, Christina, Clauditz, Till S, Hube-Magg, Claudia, Luebke, Andreas M, Simon, Ronald, Sauter, Guido, Göbel, Cosima, Weidemann, Sören, Lebok, Patrick, Dum, David, Fraune, Christoph, Izbicki, Jakob, Burandt, Eike, Schlomm, Thorsten, Huland, Hartwig, Heinzer, Hans, Haese, Alexander, Graefen, Markus, Heumann, Asmus
Publikováno v:
Neoplasia (New York, N.Y.)
Dysregulation of S100A8 is described in many different human tumor types, but its role in prostate cancer is unknown. To evaluate the clinical relevance of S100A8 expression in prostate cancer, a tissue microarray containing 13,665 tumors was analyze
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b90e2efbd716ff494d37508443469b76
http://europepmc.org/articles/PMC6698296
http://europepmc.org/articles/PMC6698296
Autor:
Wang, Fengling, Yan, Zhongyi, Lv, Jiajia, Xin, Junfang, Dang, Yifang, Sun, Xiaoxiao, An, Yang, Qi, Yijun, Jiang, Qiying, Zhu, Wan, Li, Yongqiang, Li, Ao, Guo, Xiangqian
Publikováno v:
Neoplasia (New York, N.Y.)
Esophageal squamous cell carcinoma (ESCC) is one of the most common cancers worldwide, particularly in Asian populations, and responds poorly to conventional therapy. Subclassification of ESCCs by molecular analysis is a powerful strategy in extendin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ef6a7f77f912dcef14cf7ca643cd0ffb
http://europepmc.org/articles/PMC6495472
http://europepmc.org/articles/PMC6495472
Autor:
Adam Pennycuick, Neelam Kumar, Xidan Zhang, Mary Falzon, Krishna K. Kolluri, Ersilia Nigro, Yuki Ishii, Doraid Alrifai, Khalid Shah, Elaine Borg, Sam M. Janes
Publikováno v:
The Journal of Biological Chemistry
Malignant pleural mesothelioma (MPM) is a rare, aggressive, and incurable cancer arising from the mesothelial lining of the pleura, with few available treatment options. We recently reported that loss of function of the nuclear deubiquitinase BRCA1-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b29ae2da35ab58c009cd489419063c2
https://pubmed.ncbi.nlm.nih.gov/34597666
https://pubmed.ncbi.nlm.nih.gov/34597666
Autor:
David J. Papke, Tomotaka Ugai, Shanshan Shi, Jeffrey A. Meyerhardt, Melissa Zhao, Annacarolina da Silva, Hongmei Nan, Jonathan A. Nowak, Marios Giannakis, Shuji Ogino, Naohiko Akimoto, Tyler S. Twombly, Andrew T. Chan, Xuehong Zhang, Mai Chan Lau, Mingyang Song, Koichiro Haruki, Simeng Gu, Juha P. Väyrynen, Kenji Fujiyoshi, Kota Arima, Jennifer Borowsky, Kana Wu, Jochen K. Lennerz, Junko Kishikawa, Charles S. Fuchs
Publikováno v:
EBioMedicine
EBioMedicine, Vol 57, Iss, Pp 102860-(2020)
EBioMedicine, Vol 57, Iss, Pp 102860-(2020)
Background/Objectives: Tumour budding and poorly differentiated clusters (PDC) represent forms of tumour invasion. We hypothesised that T-cell densities (reflecting adaptive anti-tumour immunity) might be inversely associated with tumour budding and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efa593303ac10de1b212634b5ae5e126
http://europepmc.org/articles/PMC7347996
http://europepmc.org/articles/PMC7347996
Autor:
Zhouhong, Ge, Guoying, Zhou, Lucia, Campos Carrascosa, Erik, Gausvik, Patrick P C, Boor, Lisanne, Noordam, Michael, Doukas, Wojciech G, Polak, Türkan, Terkivatan, Qiuwei, Pan, R Bart, Takkenberg, Joanne, Verheij, Joris I, Erdmann, Jan N M, IJzermans, Maikel P, Peppelenbosch, Jaco, Kraan, Jaap, Kwekkeboom, Dave, Sprengers
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims TIGIT is a co-inhibitory receptor, and its suitability as a target for cancer immunotherapy in HCC is unknown. PD1 blockade is clinically effective in about 20% of advanced HCC patients. Here we aim to determine whether co-blockade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::be702a3d317a527566787fa88dbfc34b
https://pubmed.ncbi.nlm.nih.gov/33781741
https://pubmed.ncbi.nlm.nih.gov/33781741
Autor:
Michelangelo Foti, Olivia Bejuy, Christine Maeder, Marta Correia de Sousa, Monika Gjorgjieva, Claudio De Vito, Laura Rubbia-Brandt, Dobrochna Dolicka, Margot Fournier, Cyril Sobolewski, Didier J. Colin, Flavien Berthou, Perry J. Blackshear
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology (2020)
Cellular and Molecular Gastroenterology and Hepatology (2020)
Background & Aims Tristetraprolin (TTP) is a key post-transcriptional regulator of inflammatory and oncogenic transcripts. Accordingly, TTP was reported to act as a tumor suppressor in specific cancers. Herein, we investigated how TTP contributes to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e04acdfadc7dd7cf24b47a30be60cc1a
https://pubmed.ncbi.nlm.nih.gov/32987153
https://pubmed.ncbi.nlm.nih.gov/32987153