Zobrazeno 1 - 10
of 97
pro vyhledávání: '"TM Dexter"'
Publikováno v:
Blood. 87:1957-1961
A human O6-alkylguanine-DNA-alkyltransferase (ATase) cDNA-containing retrovirus was used to infect murine long-term primary bone marrow cultures. High levels of ATase expression were obtained, and colony- forming cells of the granulocyte-macrophage l
Publikováno v:
Blood. 83:3491-3499
To examine the potential role of stem-cell factor (SCF) in cancer chemotherapy, we have administered it to mice either before or after 5- fluorouracil (5-FU). When polyethylene glycolated (PEG-ylated) SCF was administered to mice before 5-FU, it had
Autor:
MH Gilleece, TM Dexter
Publikováno v:
Reviews in Clinical Gerontology. 3:317-325
Autor:
TM Dexter, Maria H. Gilleece
Publikováno v:
Blood. 82:807-812
The humanized antibody CAMPATH-1H has been shown in pilot studies to be beneficial in the treatment of lymphoid malignancy and other lymphoproliferative diseases. The antigen recognized by this antibody is not confined to lymphoid cells, and work wit
Autor:
Peter L. Stern, Maria H. Gilleece, Nydia G Testa, Anna K Ghosh, J. H. Scarffe, C M Heyworth, Eric M. Bonnem, TM Dexter
Publikováno v:
British Journal of Cancer
Recombinant Interleukin 4 was administered by subcutaneous injection at daily doses of 0.5, 1.0 or 5.0 micrograms kg-1 to nine patients as part of a Phase I Dose Toxicity Study. Dose limiting toxicity was reached at 5 micrograms kg-1 day-1. Symptoms
Publikováno v:
Blood. 78:961-966
Stem cell factor (SCF) is the ligand for the receptor encoded by the c- kit proto-oncogene. Mutations of either c-kit or the SCF gene are responsible for the defects of W and SI mutant mice, which both suffer a macrocytic anemia, the former associate
Publikováno v:
Blood. 77:2154-2159
Myeloid cell kinetics in mice treated with pure hematopoietic growth factors have been investigated using tritiated thymidine labeling and autoradiography. Mice were injected subcutaneously with 125 micrograms/kg granulocyte colony-stimulating factor
Publikováno v:
Cell. 64:1163-1173
Multipotent murine stem cell lines (FDC-Pmix) depend on IL-3 for self-renewal and proliferation and can be induced to differentiate into multiple hematopoietic lineages. Single FDC-Pmix cells infected with retroviral vectors expressing GM-CSF are ind
Publikováno v:
Scopus-Elsevier
The major effect of granulocyte colony-stimulating factor (G-CSF) is to induce neutrophilia in previously untreated animals or after chemotherapy or marrow transplantation in humans, primates and rodents. In addition, it has been reported that migrat
Publikováno v:
Blood. 75:2118-2129
We have studied the effects of recombinant human granulocyte colony- stimulating factor (rhG-CSF), hG macrophage-CSF (hGM-CSF), and gibbon interleukin-3 (gIL-3) on cell proliferation and differentiation in human long-term bone marrow culture (LTBMC).