Zobrazeno 1 - 10
of 6 495
pro vyhledávání: '"TLR9)"'
Autor:
Mohammadreza Kosari, Afsaneh Asgari Taei, Andis Klegeris, Sevim Soleimani, Arian Tavasol, Kimia Jazi, Kimia Eyvani, Ashkan Bahrami, Zahra Farrokhi, Farnoosh Vosough, Faraz Rahmani Khajeh, Saleh Behzadi, Zohreh Zamani
Publikováno v:
Caspian Journal of Neurological Sciences, Vol 10, Iss 3, Pp 151-168 (2024)
Background: Parkinson disease (PD) is a prevalent neurodegenerative disorder affecting dopaminergic neurons in the substantia nigra (SN). Neuroinflammation has a vital role in PD pathophysiology. Objectives: This study assesses whether the neuroinfla
Externí odkaz:
https://doaj.org/article/ee898c1994754acd8687184871d600e5
Publikováno v:
Advanced Science, Vol 11, Iss 41, Pp n/a-n/a (2024)
Abstract The effectiveness of Toll‐like 9 agonists (CpG) as an adjuvant for tumor immunotherapy is restricted due to their insufficient ability to activate anti‐tumor immunity. To address that, the common nutrient metal ions are explored (Mn2+, C
Externí odkaz:
https://doaj.org/article/5bf23fd39bbf4256ae17f8aa30b5f030
Autor:
Anna R. Mahr, Maia M. C. Bennett-Boehm, Frederik H. Rothemejer, Isabelle S. Weber, Alexander K. Regan, Josh Q. Franzen, Cami R. Bisson, Angela N. Truong, Rikke Olesen, Mariane H. Schleimann, Claudia M. Rauter, Audrey L. Smith, Dalia El-Gamal, Ole S. Søgaard, Martin Tolstrup, Paul W. Denton
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract There are two known mechanisms by which natural killer (NK) cells recognize and kill diseased targets: (i) direct killing and (ii) antibody-dependent cell-mediated cytotoxicity (ADCC). We investigated an indirect NK cell activation strategy
Externí odkaz:
https://doaj.org/article/85906b314a2a4acaaca1f37e36865354
Publikováno v:
陆军军医大学学报, Vol 46, Iss 8, Pp 829-836 (2024)
Objective To investigate the protective effect of Toll-like receptor (TLR) 2 /TLR9 agonists, Pam2CSK4 (Pam) and CpG ODN (CpG) on mice infected with Acinetobacter baumannii (Ab) in the lungs. Methods Female C57 mice (6~8 weeks old) were randomly divid
Externí odkaz:
https://doaj.org/article/45b11a81db0b416f9f1c3d1b7b9c7996
Publikováno v:
BMC Rheumatology, Vol 8, Iss 1, Pp 1-12 (2024)
Abstract Background Behcet’s disease (BD) is a multisystem and multifactorial autoimmune disease characterized by relapsing episodes of oral aphthae, genital ulcers, and ocular and skin lesions. Toll-like receptor 9 (TLR9) has pro-inflammatory role
Externí odkaz:
https://doaj.org/article/6c399c72cb684da390233a8386ae4991
Autor:
Dandan Yi, Menghui Wang, Xia Liu, Lanqian Qin, Yu Liu, Linyi Zhao, Ying Peng, Zhengmin Liang, Jiakang He
Publikováno v:
Antioxidants, Vol 13, Iss 10, p 1265 (2024)
Salmonella enteritidis (SE) infection disrupts the homeostasis of the intestinal microbiota, causing an intestinal inflammatory response and posing a great threat to human and animal health. The unreasonable use of antibiotics has led to an increase
Externí odkaz:
https://doaj.org/article/8c91748d66f145f8a2e6affd3a424640
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Nada S. Alakhras, Christopher A. Moreland, Li Chin Wong, Priyam Raut, Sid Kamalakaran, Yi Wen, Robert W. Siegel, Laurent P. Malherbe
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Recombinant adeno-associated virus (AAV) vectors have emerged as the preferred platform for gene therapy of rare human diseases. Despite the clinical promise, host immune responses to AAV vectors and transgene remain a major barrier to the developmen
Externí odkaz:
https://doaj.org/article/5d526ac1f027445c881a5c370ba6217e
Autor:
Rui Zhang, Disi Zhang, Yilan Luo, Yunyan Sun, Ci Duan, Jiapeng Yang, Jia Wei, Xianshi Li, Yanqi Lu, Xun Lai
Publikováno v:
Cancer Medicine, Vol 13, Iss 11, Pp n/a-n/a (2024)
Abstract Background Promising outcomes have been observed in multiple myeloma (MM) with the use of immunotherapies, specifically chimeric antigen receptor T (CAR‐T) cell therapy. However, a portion of MM patients do not respond to CAR‐T therapy,
Externí odkaz:
https://doaj.org/article/c4e2c562d7f348d7bbc4ef56adbb2a08