Zobrazeno 1 - 10
of 513
pro vyhledávání: '"TLR4 signaling"'
Autor:
Kailibinuer Kadier, Tian Niu, Baoli Ding, Boya Chen, Xuxin Qi, Danni Chen, Xirui Cheng, Yizheng Fang, Jiahao Zhou, Wenyi Zhao, Zeqi Liu, Yi Yuan, Zhan Zhou, Xiaowu Dong, Bo Yang, Qiaojun He, Ji Cao, Li Jiang, Cheng‐Liang Zhu
Publikováno v:
Advanced Science, Vol 11, Iss 36, Pp n/a-n/a (2024)
Abstract Class IIa histone deacetylases (Class IIa HDACs) play critical roles in regulating essential cellular metabolism and inflammatory pathways. However, dissecting the specific roles of each class IIa HDAC isoform is hindered by the pan‐inhibi
Externí odkaz:
https://doaj.org/article/d94f18ab60fb45f8a9a05002ad76974a
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 281, Iss , Pp 116666- (2024)
Ochratoxin A (OTA) is a common mycotoxin that causes intestinal injury in humans and various animal species. OTA may lead to intestinal injury in offspring due to the maternal effect. The aim of this study was to investigate the mechanism of embryo i
Externí odkaz:
https://doaj.org/article/d09d6fb120e54739bad5e098f21d0a7a
Autor:
Yaowen Luo, Junkai Cheng, Yihao Fu, Min Zhang, Maorong Gou, Juan Li, Xiaobing Li, Jing Bai, Yuefei Zhou, Lei Zhang, Dakuan Gao
Publikováno v:
Biological Procedures Online, Vol 25, Iss 1, Pp 1-21 (2023)
Abstract Background Ischemic stroke (IS) occurs when a blood vessel supplying the brain becomes obstructed, resulting in cerebral ischemia. This type of stroke accounts for approximately 87% of all strokes. Globally, IS leads to high mortality and po
Externí odkaz:
https://doaj.org/article/3c1c16180ff04ad8a821f1ef9c00f9ab
Autor:
Arianna Giacomini, Marta Turati, Elisabetta Grillo, Sara Rezzola, Gaia Cristina Ghedini, Ander Churruca Schuind, Eleonora Foglio, Federica Maccarinelli, Jessica Faletti, Serena Filiberti, Angela Chambery, Mariangela Valletta, Laura Melocchi, Stephanie Gofflot, Barbara Chiavarina, Andrei Turtoi, Marco Presta, Roberto Ronca
Publikováno v:
Experimental Hematology & Oncology, Vol 12, Iss 1, Pp 1-15 (2023)
Abstract Background The pattern recognition receptor long pentraxin-3 (PTX3) plays conflicting roles in cancer by acting as an oncosuppressor or as a pro-tumor mediator depending on tumor context. Triple negative breast cancer (TNBC) represents the m
Externí odkaz:
https://doaj.org/article/ce088ea03fb14b48ad1226cfd227f339
Autor:
Zhongxing Wang, Dongyu Zhu, Yuting Zhang, Fufang Xia, Jiaying Zhu, Jianjun Dai, Xiangkai Zhuge
Publikováno v:
Microbial Cell Factories, Vol 22, Iss 1, Pp 1-20 (2023)
Abstract Background Avian pathogenic Escherichia coli (APEC) is the major pathogen causing important avian diseases in poultry. As an important subtype of extraintestinal pathogenic E. coli, APEC has zoonotic potential and is considered a foodborne p
Externí odkaz:
https://doaj.org/article/849dfc15769c4c0eaa2e734205503758
Autor:
Bristy Basak, Sachiko Akashi-Takamura
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Lipopolysaccharide (LPS) induces potent cell activation via Toll-like receptor 4/myeloid differentiation protein 2 (TLR4/MD-2), often leading to septic death and cytokine storm. TLR4 signaling is diverted to the classical acute innate immune, inflamm
Externí odkaz:
https://doaj.org/article/c918e4d04c154ad899d7d128ba37671b
Publikováno v:
Current Research in Toxicology, Vol 7, Iss , Pp 100196- (2024)
This study aimed to evaluate the preventive efficacy of tocotrienol in inhibiting the nuclear factor-kappa B (NF-κB) mediated inflammation pathways in colorectal cancer. We utilized the azoxymethane (AOM) and dextran sulfate sodium salt (DSS) to ind
Externí odkaz:
https://doaj.org/article/c68e65ef6901417ebb10480de948edac
Autor:
Li-Shan Yan, Brian Chi-Yan Cheng, Yi-Wei Wang, Shuo-Feng Zhang, Xin-Yu Qiu, Jian-Ying Kang, Chao Zhang, Zhan-Hong Jia, Gan Luo, Yi Zhang
Publikováno v:
Heliyon, Vol 9, Iss 11, Pp e21635- (2023)
Background: Xuelian injection (XI), a classic preparation extracted from Saussureae Involucratae Herba, has been clinically used to manage rheumatoid arthritis (RA) for nearly twenty years in China. However, the underlying anti-RA mechanism of XI rem
Externí odkaz:
https://doaj.org/article/25da0cb2774f4e11962f813f66b52b9d
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 17, Pp 297-312 (2023)
Li-Shan Yan,1,* Shuang Cui,1,* Brian Chi-Yan Cheng,2 Xing-Bin Yin,1 Yi-Wei Wang,1 Xin-Yu Qiu,1 Ci-Ren Nima,3 Yi Zhang,1 Shuo-Feng Zhang1 1School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, People’s Republic o
Externí odkaz:
https://doaj.org/article/af72a9e63c7e49ea8bef9e9447aac9e4
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