Zobrazeno 1 - 10
of 4 705
pro vyhledávání: '"TLR3"'
Autor:
Md Fazlul Haque, Salisa Benjaskulluecha, Atsadang Boonmee, Pornrat Kongkavitoon, Benjawan Wongprom, Thitiporn Pattarakankul, Rahat Ongratanaphol, Kittitach Sri-ngern-ngam, Chitsuda Pongma, Benjawan Saechue, Patipark Kueanjinda, Takashi Kobayashi, Asada Leelahavanichkul, Tanapat Palaga
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract O6-methylguanine-DNA methyltransferase (MGMT) is a DNA damage repair enzyme. The roles of this enzyme in immune cells remain unclear. In this study, we explored the roles of MGMT in bone marrow-derived murine macrophages (BMMs) via the use o
Externí odkaz:
https://doaj.org/article/9f415c7723054e2197a34aa9b7fc6bf8
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Background Sorafenib is a standard therapeutic agent for advanced hepatocellular carcinoma (HCC). However, its efficacy is moderate, as the survival of patients is prolonged for only a few months, and the response rate is low. The mechanism
Externí odkaz:
https://doaj.org/article/237570e073144c1e8ef92684e41394c4
Autor:
Tetou Soumbara, Crystel Bonnet, Cheikh Tijani Hamed, Fatimetou Veten, Mohamed Hemeyine, F-Zahra Fall-Malick, Mohamed Mahmoud El Yezid, Aichetou Diallo, Moustapha Mouhamedou Mounah, Ahmed Houmeida
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background Toll-Like receptors (TLRs) play an important role in the immune response during hepatitis B virus (HBV) infection. In this study, we evaluated the association between two SNP variants (TLR3 rs3775290 and TLR4 rs4986790) and suscep
Externí odkaz:
https://doaj.org/article/f74d192e75f0460991b71ccdbbb00e5f
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 180, Iss , Pp 117456- (2024)
Transfusion-related lung injury (TRALI) poses a significant risk following blood transfusion and remains the primary cause of transfusion-related morbidity and mortality, primarily driven by the activation of immune cells through anti-major histocomp
Externí odkaz:
https://doaj.org/article/1ecf31e2ed0f482c9f2c2b9f3591ab56
Akademický článek
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Autor:
Maria Y. Najem, Ryan N. Rys, Sandrine Laurance, François‐René Bertin, Virginie Gourdou‐Latyszenok, Lénaïck Gourhant, Lauriane Le Gall, Rozenn Le Corre, Francis Couturaud, Mark D. Blostein, Catherine A. Lemarié
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 15 (2024)
Background Venous thromboembolism is associated with endothelial cell activation that contributes to the inflammation‐dependent activation of the coagulation system. Cellular damage is associated with the release of different species of extracellul
Externí odkaz:
https://doaj.org/article/67f57dfc8de74c6982911de9874d5841
Publikováno v:
Small Science, Vol 4, Iss 7, Pp n/a-n/a (2024)
Intratumoral immunotherapies are those that are administered directly into a tumor to remodel the local tumor microenvironment and stimulate systemic anti‐tumor immunity. Small molecule toll‐like receptor (TLR) agonists are undergoing development
Externí odkaz:
https://doaj.org/article/035699a60964485381650ac24c04dcf9
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Triple negative breast cancer (TNBC) is a heterogenous disease that disproportionately affects Black women. TNBC outcomes among Black women are dismal secondary to multiple factors, such as poor healthcare accessibility resulting in delays in diagnos
Externí odkaz:
https://doaj.org/article/49bee30d362e4cf481334f557996d97a
Autor:
Nasir Arefinia, Parsa Banafi, Mohammad Amin Zarezadeh, Hawra Shah Mousawi, Ramin Yaghobi, Mehrdad Farokhnia, Jamal Sarvari
Publikováno v:
Data in Brief, Vol 54, Iss , Pp 110498- (2024)
The prognosis of COVID-19 could influence by innate immune sensors such as toll-like receptors (TLRs). The purpose of this data was to investigate TLR3, 7, and 8 expression levels in COVID-19 patients and their relationship to outcome of disease.75 c
Externí odkaz:
https://doaj.org/article/a165769902754db8a945926f368e02bf
Autor:
Hongyan Xie, Dianhui Chen, Yuanfa Feng, Feng Mo, Lin Liu, Junmin Xing, Wei Xiao, Yumei Gong, Shanni Tang, Zhengrong Tan, Guikuan Liang, Shan Zhao, Weiguo Yin, Jun Huang
Publikováno v:
BMC Immunology, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract Background Despite the functions of TLRs in the parasitic infections have been extensively reported, few studies have addressed the role of TLR3 in the immune response to Schistosoma japonicum infections. The aim of this study was to investi
Externí odkaz:
https://doaj.org/article/132c5eeeab9b404d860fdbb57639a683