Zobrazeno 1 - 10
of 12 880
pro vyhledávání: '"TLR2"'
Publikováno v:
Медицинская иммунология, Vol 26, Iss 4, Pp 711-716 (2024)
TLR2 is an exceptional pattern-recognizing receptor because of its ability to heterodimerise with different types of TLRs, which allows it to recognize a wide range of molecular structures on the surface of pathogens. Polymorphisms in genes involved
Externí odkaz:
https://doaj.org/article/72e52993f1694815a430cd012bf50fac
Autor:
Daping Xie, Congwei Han, Chonghao Chen, Zhencheng Liao, Senio Campos de Souza, Yiming Niu, João F. Mano, Lei Dong, Chunming Wang
Publikováno v:
Bioactive Materials, Vol 37, Iss , Pp 315-330 (2024)
Cancer vaccination holds great promise for cancer treatment, but its effectiveness is hindered by suboptimal activation of CD8+ cytotoxic T lymphocytes, which are potent effectors to mediate anti-tumor immune responses. A possible solution is to swit
Externí odkaz:
https://doaj.org/article/63cce374d08d4b5183ab56a352bb148e
Autor:
Anthea Miller, Giorgia Pia Lombardo, Giuseppina Rizzo, Magdalena Kotanska, Giuseppinella Melita, Socrate Pallio, Alba Migliorato, Giuseppina Cutroneo, Simona Pergolizzi
Publikováno v:
Gastroenterology Insights, Vol 15, Iss 3, Pp 541-554 (2024)
Inflammatory bowel diseases (IBDs) represent multifactorial chronic inflammatory conditions of the gastrointestinal tract. The main IBDs are Crohn’s disease (CD) and ulcerative colitis (UC). CD may cause perforation, stricture or transmural inflamm
Externí odkaz:
https://doaj.org/article/24816025f6e64b87a2245d8cdc5539a6
Autor:
Davoud Ghazanfari, Maria Cecilia Courreges, Lydia E. Belinski, Michael J. Hogrell, Jacob Lloyd, Stephen C. Bergmeier, Kelly D. McCall, Douglas J. Goetz
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract During a SARS-CoV-2 infection, macrophages recognize viral components resulting in cytokine production. While this response fuels virus elimination, overexpression of cytokines can lead to severe COVID-19. Previous studies suggest that the s
Externí odkaz:
https://doaj.org/article/56233cae8bb2417da30fac712d7f764f
Publikováno v:
Venereology, Vol 3, Iss 1, Pp 26-34 (2024)
The Arg753Gln polymorphism in Toll-like receptor 2 has been associated with an increased risk of bacterial infections as well as with protection from the late stages of Lyme disease and the acquisition of syphilis. In this study, we determined the pr
Externí odkaz:
https://doaj.org/article/8e0c9e2f8ed54562b0a8618afab75e91
Autor:
Han Wang, Qi Xu, Heng Heng, Wenxing Zhao, Hongyuhang Ni, Kaichao Chen, Bill Kwan Wai Chan, Yang Tang, Miaomiao Xie, Mingxiu Peng, Edward Wai Chi Chan, Guan Yang, Sheng Chen
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105340- (2024)
Summary: Background: The continuous emergence of multidrug-resistant (MDR) Acinetobacter baumannii (Ab) strains poses further challenges in its control and clinical management. It is necessary to decipher the mechanisms underlying the high mortality
Externí odkaz:
https://doaj.org/article/877794228a95425d93ea26b6abe71772
Publikováno v:
Heliyon, Vol 10, Iss 16, Pp e35950- (2024)
Severe fever with thrombocytopenia syndrome (SFTS) is a recently identified infectious ailment triggered by a new strain of bunyavirus. It is distinguished by elevated fatality rates, ranging from 12 % to 30 %. The mechanism underlying the developmen
Externí odkaz:
https://doaj.org/article/4e25e37c49a54795824f133a1ddd399e
Autor:
Aleksandra Wielento, Grzegorz P. Bereta, Katarzyna B. Łagosz-Ćwik, Sigrun Eick, Richard J. Lamont, Aleksander M. Grabiec, Jan Potempa
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/ca9c7681c329454dabeb02772c8818ba
Autor:
Bo Yan, Pan Liao, Fangyuan Cheng, Conglin Wang, Jieying Zhang, Zhaoli Han, Yaru Liu, Lan Zhang, Wei Zhang, Meimei Li, Dai Li, Fanglian Chen, Ping Lei
Publikováno v:
Experimental Gerontology, Vol 193, Iss , Pp 112464- (2024)
Background: Vascular dementia (VaD), the second most prevalent type of dementia, lacks a well-defined cause and effective treatment. Our objective was to utilize bioinformatics analysis to discover the fundamental disease-causing genes and pathologic
Externí odkaz:
https://doaj.org/article/726ff1e062964957929a6466c1cef6f8
Publikováno v:
陆军军医大学学报, Vol 46, Iss 8, Pp 829-836 (2024)
Objective To investigate the protective effect of Toll-like receptor (TLR) 2 /TLR9 agonists, Pam2CSK4 (Pam) and CpG ODN (CpG) on mice infected with Acinetobacter baumannii (Ab) in the lungs. Methods Female C57 mice (6~8 weeks old) were randomly divid
Externí odkaz:
https://doaj.org/article/45b11a81db0b416f9f1c3d1b7b9c7996