Zobrazeno 1 - 10
of 460
pro vyhledávání: '"TLR‐2"'
Autor:
Mohammad Haque, Lauren Kaminsky, Raz Abdulqadir, Jessica Engers, Evgeny Kovtunov, Manmeet Rawat, Rana Al-Sadi, Thomas Y. Ma
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundDefective intestinal epithelial tight junction (TJ), characterized by an increase in intestinal TJ permeability, has been shown to play a critical role in the pathogenesis of inflammatory bowel disease (IBD). Tumor necrosis factor-α (TNF-
Externí odkaz:
https://doaj.org/article/3d6dadc85d734c34991bd87666b04db4
Autor:
Jainal Arifin, Muhammad Nasrum Massi, Karya Triko Biakto, Agussalim Bukhari, Zairin Noor, Muhammad Phetrus Johan
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 18, Iss 1, Pp 1-9 (2023)
Abstract Background Tuberculosis spondylitis accounts for approximately 50% of all cases of skeletal tuberculosis. Vitamin D plays a role in the immune system. Vitamin D helps in the activation of TLR-2 and TLR-4, which play a role in the process of
Externí odkaz:
https://doaj.org/article/b08300005b124d70a897f223b5498470
Publikováno v:
Microbiology Research, Vol 14, Iss 2, Pp 559-579 (2023)
The role of microRNAs (miRNAs) in Mycobacterium fortuitum pathogenesis is not well illustrated. Using zebrafish kidney macrophages (ZFKM) we observed that M. fortuitum triggers miR-155 expression, and the TLR-2/NF-κB axis plays a key role in initiat
Externí odkaz:
https://doaj.org/article/73726855d88a455a8ac160aa185d6e26
Publikováno v:
Ibn Al-Haitham Journal for Pure and Applied Sciences, Vol 36, Iss 4 (2023)
Periodontal diseases (PD) are worldwide diseases of humans either in childhood or adults. The present study aimed to find the correlation between some demographic and saliva immunological factors including the determination of saliva TLR-2, IL6, CRP,
Externí odkaz:
https://doaj.org/article/e727ca68586248b5b517a5d77073cf2f
Autor:
Arshad Hasan, Talat Roome, Mohsin Wahid, Shazia Akbar Ansari, Hira Akhtar, Syeda Neha Ahmed Jilani, Amber Kiyani
Publikováno v:
BMC Oral Health, Vol 22, Iss 1, Pp 1-15 (2022)
Abstract Background Toll like receptors (TLR) 2 and 4 present on innate immune cells of the dental pulp detect cariogenic bacteria. Along with bacteria, C. albicans may also be present in dental caries. The presence of C. albicans can be detected by
Externí odkaz:
https://doaj.org/article/6eefae0dd4724bfc929795c75442b41a
Akademický článek
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Akademický článek
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Autor:
Chen Zhang, Zhengxiang Cheng, Yuanyuan Zhou, Ziyi Yu, Hongyu Mai, Changhao Xu, Jing Zhang, Jiali Wang
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 3, Pp n/a-n/a (2023)
Abstract In patients with mild osteoarthritis (OA), two to four monthly injections are required for 6 months due to the degradation of hyaluronic acid (HA) by peroxidative cleavage and hyaluronidase. However, frequent injections may lead to local inf
Externí odkaz:
https://doaj.org/article/a368c336c44c456ea85452ffa535d34c
Akademický článek
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Autor:
Caio C. B. Bomfim, Logan Fisher, Eduardo P. Amaral, Lara Mittereder, Katelyn McCann, André A. S. Correa, Sivaranjani Namasivayam, Muthulekha Swamydas, Mahtab Moayeri, Jonathan M. Weiss, Raj Chari, Daniel W. McVicar, Diego L. Costa, Maria R. D’Império Lima, Alan Sher
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Irg1 is an enzyme that generates itaconate, a metabolite that plays a key role in the regulation of inflammatory responses. Previous studies have implicated Irg1 as an important mediator in preventing excessive inflammation and tissue damage in Mycob
Externí odkaz:
https://doaj.org/article/829c533eabff4b7a98e063262dae07c5