Forced degradation of gliquidone and development of validated stability-indicating HPLC and TLC methods

Autor: Aya Helmy Helmy, Ali M. Yehia, Nadia F. Youssef, Mohamed R. Elghobashy

Publikováno v: Brazilian Journal of Pharmaceutical Sciences, Vol 54, Iss 3 (2018)
Brazilian Journal of Pharmaceutical Sciences; Vol. 54 No. 3 (2018); e00223
Brazilian Journal of Pharmaceutical Sciences; Vol. 54 Núm. 3 (2018); e00223
Brazilian Journal of Pharmaceutical Sciences; v. 54 n. 3 (2018); e00223
Brazilian Journal of Pharmaceutical Sciences
Universidade de São Paulo (USP)
instacron:USP

Forced degradation studies of gliquidone were conducted under different stress conditions. Three degradates were observed upon using HPLC and TLC and elucidated by LC-MS and IR. HPLC method was performed on C18 column using methanol-water (85:15 v/v)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c1ac345b62c2f7db7a6501457d80646
https://doi.org/10.1590/s2175-97902018000317223