Knihovna AV ČR, v. v. i.
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Zobrazeno 1 - 10 of 157 pro vyhledávání: '"TLC, thin layer chromatography"'
1
Akademický článek
Compound Characterization of a Mucuna Seed Extract: L-Dopa, Arginine, Stizolamine, and Some Fructooligosaccharides
Autor: Ana Lilia Hernández-Orihuela, Karla Viridiana Castro-Cerritos, Mercedes Guadalupe López, Agustino Martínez-Antonio
Publikováno v: Compounds, Vol 3, Iss 1, Pp 1-16 (2022)
Human societies demand sustainable alternatives for goods and services. Plants are sustainable sources of important metabolites with beneficial impacts on human health. There are many reported methodologies and commercial suppliers for extract prepar
Externí odkaz: https://doaj.org/article/266942cd3b5942ca8546805ac274e5e9
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2
Piper crocatum Ruiz & Pav. ameliorates wound healing through p53, E-cadherin and SOD1 pathways on wounded hyperglycemia fibroblasts
Autor: Dwi Aris Agung Nugrahaningsih, Firas Fneish, Christantie Effendy, Mae Sri Hartati Wahyuningsih, Gerhard Fortwengel, Andina Setyawati
Publikováno v: Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences, Vol 28, Iss 12, Pp 7257-7268 (2021)
Graphical abstract
Highlights • The most active fraction of Piper crocatum Ruiz & Pav (FIV), originated from methanol extracts and wash benzene-soluble extracts, has diabetic wound healing activities on wounded hyperglycemia fibroblasts. • F
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae32efb978030766b31a20bb7a472cf
http://europepmc.org/articles/PMC8626332
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3
Akademický článek
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4
Discovery of thiosemicarbazone derivatives as effective New Delhi metallo-β-lactamase-1 (NDM-1) inhibitors against NDM-1 producing clinical isolates
Autor: Xin-Hui Zhang, Hong-Min Liu, Yongfang Yao, Li-Ying Ma, Xue-Jian Feng, Qin Shangshang, Tingting Yu, Bing Zhao, De-Quan Yu, Xiaoling Zhang, Ying Liu
Publikováno v: Acta Pharmaceutica Sinica B, Vol 11, Iss 1, Pp 203-221 (2021)
Acta Pharmaceutica Sinica. B
New Delhi metallo-β-lactamase-1 (NDM-1) is capable of hydrolyzing nearly all β-lactam antibiotics, posing an emerging threat to public health. There are currently less effective treatment options for treating NDM-1 positive “superbug”, and no p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c44e2471539ae24953ab00f10282f4be
http://www.sciencedirect.com/science/article/pii/S2211383520306316
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5
Discovery of a potent and dual-selective bisubstrate inhibitor for protein arginine methyltransferase 4/5
Autor: Dongxing Chen, Rong Huang, Youchao Deng, Ayad A. Al-Hamashi, Guangping Dong
Publikováno v: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2709-2718 (2021)
Protein arginine methyltransferases (PRMTs) have been implicated in the progression of many diseases. Understanding substrate recognition and specificity of individual PRMT would facilitate the discovery of selective inhibitors towards future drug di
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1953181d586500187a3f64527a8d59c
http://europepmc.org/articles/PMC8463262
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6
Isolation of diverse bioactive compounds from Euphorbia balsamifera: Cytotoxicity and antibacterial activity studies
Autor: Samir A. Mahgoub, Abdulrahman I. Almansour, Salha M Aljubiri, Kamel H. Shaker, Mohamed Shaaban
Publikováno v: Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences, Vol 28, Iss 1, Pp 417-426 (2021)
Antibacterial and cytotoxic activities of Euphorbia balsamifera, fractions and pure compounds were evaluated. The cytotoxic assays for HCT116, HePG2 and MCF7 showed a significant IC50: 54.7 and 76.2 µg/mL of non-polar fraction "n-hexane" against HCT
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89a0416a4cbd358fb5a70cda85c76270
http://europepmc.org/articles/PMC7783668
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7
A new isoflavonol and other constituents from Cameroonian propolis and evaluation of their anti-inflammatory, antifungal and antioxidant potential
Autor: Mathieu Sawalda, Rufin Marie Toghueo Kouipou, Justin Jacquin Epah Epanda, Emmanuel Talla, Godloves Fru Chi, Joseph Tanyi Mbafor, Alfred Ngenge Tamfu, Almas Jabeen, Tariq Ahmad Baig, Maurice Tagatsing Fotsing, Farzana Shaheen
Publikováno v: Saudi Journal of Biological Sciences, Vol 27, Iss 6, Pp 1659-1666 (2020)
Saudi Journal of Biological Sciences
Propolis is rich in diverse bioactive compounds. Propolis samples were collected from three localities of Cameroon and used in the study. Column chromatography separation of propolis MeOH:DCM (50:50) extracts yielded a new isoflavonol, 2-hydroxy-8-pr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19870aa411efdfc77a70968de49a3a0b
http://www.sciencedirect.com/science/article/pii/S1319562X19302694
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8
Design, synthesis and pharmacological evaluation of 4-(3-chloro-4-(3-cyclopropylthioureido)-2-fluorophenoxy)-7-methoxyquinoline-6-carboxamide (WXFL-152): a novel triple angiokinase inhibitor for cancer therapy
Autor: Zhuowei Liu, Yuxi Wang, Chengjian Zhao, Yang Zhang, Manyu Zhao, Jinliang Yang, Yuqin Yao, Peng Li, Chen Zhengxia, Xiaoxin Chen, Chaofeng Long
Publikováno v: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 10, Iss 8, Pp 1453-1475 (2020)
Angiokinases, such as vascular endothelial-, fibroblast- and platelet-derived growth factor receptors (VEGFRs, FGFRs and PDGFRs) play crucial roles in tumor angiogenesis. Anti-angiogenesis therapy using multi-angiokinase inhibitor has achieved great
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a6380c470a4be26e380966eab21f579
http://europepmc.org/articles/PMC7488503
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9
Synthesis and anti-Toxoplasma activity of indole-triazole compounds on tachyzoites of RH strain
Autor: Mohammad Saleh Bahreini, Aida Iraji, Najmeh Edraki, Ali Arab Monfared, Qasem Asgari
Publikováno v: Annals of Medicine and Surgery
Background Conventional treatment for toxoplasmosis have severe side effects and the inability to completely eradicate the disease. Therefore, the acquisition of new anti-Toxoplasma drugs has always been of interest among researchers. In the present
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b610efb00e4b3d1ec39d6e257e020619
http://europepmc.org/articles/PMC8777237
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10
Identification of novel neutrophil very long chain plasmalogen molecular species and their myeloperoxidase mediated oxidation products in human sepsis
Autor: Kaushalya Amunugama, Matthew J. Jellinek, Megan P. Kilroy, Carolyn J. Albert, Valerio Rasi, Daniel F. Hoft, Michael G.S. Shashaty, Nuala J. Meyer, David A. Ford
Publikováno v: Redox Biology
Redox Biology, Vol 48, Iss, Pp 102208-(2021)
Plasmalogens are a class of phospholipids containing vinyl ether linked aliphatic groups at the sn-1 position. Plasmalogens are known to contain 16- and 18-carbon aliphatic groups at the sn-1 position. Here, we reveal that the human neutrophil plasme
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::991be0461f8ad91bb141668ad24ed6d9
https://pubmed.ncbi.nlm.nih.gov/34902676
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