Zobrazeno 1 - 10
of 424
pro vyhledávání: '"TK6"'
Autor:
Noelia Perez-Diaz, Ewelina Hoffman, Julie Clements, Rebecca Cruickshank, Ann Doherty, Daniel Ebner, Joanne Elloway, Jianan Fu, Joanne Kelsall, Val Millar, Ouarda Saib, Andrew Scott, Ian Woods, Victoria Hutter
Publikováno v:
Frontiers in Toxicology, Vol 5 (2023)
Introduction:In vitro approaches are an essential tool in screening for toxicity of new chemicals, products and therapeutics. To increase the reproducibility and human relevance of these in vitro assessments, it is advocated to remove animal-derived
Externí odkaz:
https://doaj.org/article/5f4beb6e9c5a4961acd2c0f174e2524e
Akademický článek
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Akademický článek
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Autor:
Manabu Yasui, Takayuki Fukuda, Akiko Ukai, Jiro Maniwa, Tadashi Imamura, Tsuneo Hashizume, Haruna Yamamoto, Kaori Shibuya, Kazunori Narumi, Yohei Fujiishi, Emiko Okada, Saori Fujishima, Mika Yamamoto, Naoko Otani, Maki Nakamura, Ryoichi Nishimura, Maya Ueda, Masayuki Mishima, Kaori Matsuzaki, Akira Takeiri, Kenji Tanaka, Yuki Okada, Munehiro Nakagawa, Shuichi Hamada, Akihiko Kajikawa, Hiroshi Honda, Jun Adachi, Kentaro Misaki, Kumiko Ogawa, Masamitsu Honma
Publikováno v:
Genes and Environment, Vol 43, Iss 1, Pp 1-19 (2021)
Abstract Background Conflicting results between bacterial mutagenicity tests (the Ames test) and mammalian carcinogenicity tests might be due to species differences in metabolism, genome structure, and DNA repair systems. Mutagenicity assays using hu
Externí odkaz:
https://doaj.org/article/28a26d2c8a28419a8e0d701873581be0
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
Graphical Abstract
Externí odkaz:
https://doaj.org/article/8935d441cf8a49f187c2ae99b22b3512
Publikováno v:
Cancer Management and Research, Vol Volume 11, Pp 8327-8335 (2019)
B Yudhistiara,1,2 KJ Weber,1,2 PE Huber,1,3 A Ruehle,1,3 S Brons,2,4 P Haering,5 J Debus,1,2,4,6 H Hauswald1,2,4,6 1Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg 69120, Germany; 2National Center for Radiation Research i
Externí odkaz:
https://doaj.org/article/e4fdc20a8aa043fdbae986eae74d8841
Autor:
Akira Sassa, Takayuki Fukuda, Akiko Ukai, Maki Nakamura, Michihito Takabe, Takeji Takamura-Enya, Masamitsu Honma, Manabu Yasui
Publikováno v:
Genes and Environment, Vol 41, Iss 1, Pp 1-8 (2019)
Abstract Background The human genome is constantly exposed to numerous environmental genotoxicants. To prevent the detrimental consequences induced by the expansion of damaged cells, cellular protective systems such as nucleotide excision repair (NER
Externí odkaz:
https://doaj.org/article/8fb7428c7d7241948edf555c8675a1da
Autor:
Akira Takeiri, Kaori Matsuzaki, Shigeki Motoyama, Mariko Yano, Asako Harada, Chiaki Katoh, Kenji Tanaka, Masayuki Mishima
Publikováno v:
Genes and Environment, Vol 41, Iss 1, Pp 1-15 (2019)
Abstract Background The in vitro micronucleus (MN) test is an important component of a genotoxicity test battery that evaluates chemicals. Although the standard method of manually scoring micronucleated (MNed) cells by microscope is a reliable and st
Externí odkaz:
https://doaj.org/article/fe47dc3944fd4bd3bb80d1ab7137d1bc
Autor:
B. Yudhistiara, F. Zwicker, K. J. Weber, P. E. Huber, A. Ruehle, S. Brons, P. Haering, J. Debus, S. H. Hauswald
Publikováno v:
Radiation Oncology, Vol 14, Iss 1, Pp 1-8 (2019)
Abstract Background The implementation of magnetic resonance imaging (MRI) guided radiotherapy (RT) continues to increase. Very limited in-vitro data on the interaction of ionizing radiation and magnetic fields (MF) have been published. In these expe
Externí odkaz:
https://doaj.org/article/aff7454075c8427f93c82a509991b604
Publikováno v:
Journal of Medical Physics, Vol 44, Iss 2, Pp 118-125 (2019)
Purpose/Aim: Ultraviolet C (UVC) radiation is harmful to cells and living organisms that cause direct and indirect DNA damage. UVC can also increase the inflammatory genes expression such as COX-2 that results in elevated oxidative stress that plays
Externí odkaz:
https://doaj.org/article/6faf10c4dee84592b6b25e8f4b9fe4bf