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pro vyhledávání: '"TIRAP, ‘TIR' domain containing adaptor protein"'
Autor:
Sajjan Rajpoot, Kishore K. Wary, Rachel Ibbott, Dongfang Liu, Uzma Saqib, Teresa L. M. Thurston, Mirza S. Baig
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The Toll-interleukin-1 Receptor (TIR) domain-containing adaptor protein (TIRAP) represents a key intracellular signalling molecule regulating diverse immune responses. Its capacity to function as an adaptor molecule has been widely investigated in re
Externí odkaz:
https://doaj.org/article/542f16155e9c4ca79f20441c409889c8
Autor:
Rahul Singh, Sean N. Avedissian, Vinod D. Chaudhari, Anthony T. Podany, Ganesh P. Pawar, Deepak B. Salunke, Rohini Emani, Shetty Ravi Dyavar, Courtney V. Fletcher
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 141, Iss, Pp 111794-(2021)
Biomedicine & Pharmacotherapy
Biomedicine & Pharmacotherapy
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) is the causative agent of Corona Virus Disease 2019 (COVID-19). Lower production of type I and III interferons and higher levels of inflammatory mediators upon SARS-CoV2 infection contribute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0354b118d4b1b6946482534bec88d63f
http://www.sciencedirect.com/science/article/pii/S075333222100576X
http://www.sciencedirect.com/science/article/pii/S075333222100576X
Publikováno v:
Cytokine & Growth Factor Reviews
Graphical abstract
Highlights • Systemic oxidative stress and inflammation are significant outcomes of SARS-CoV-2 infection. • Activated Gsk-3 following SARS-CoV-2 infection provoke the oxidative stress and inflammation in the host. • Gsk-
Highlights • Systemic oxidative stress and inflammation are significant outcomes of SARS-CoV-2 infection. • Activated Gsk-3 following SARS-CoV-2 infection provoke the oxidative stress and inflammation in the host. • Gsk-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2341a436aa2d7b5cd262c39784c0248d
https://pubmed.ncbi.nlm.nih.gov/32948440
https://pubmed.ncbi.nlm.nih.gov/32948440
Autor:
Sheila R. Costford, Sophie E. Hussey, Ralph A. DeFronzo, Brian Ely, Amira Klip, Nicolas Musi, Alicia Sanchez-Avila, Hanyu Liang
Publikováno v:
Bioscience Reports
Bioscience Reports, Vol 33, Iss 1, p e00004 (2012)
Bioscience Reports, Vol 33, Iss 1, p e00004 (2012)
Emerging evidence suggests that TLR (Toll-like receptor) 4 and downstream pathways [MAPKs (mitogen-activated protein kinases) and NF-κB (nuclear factor κB)] play an important role in the pathogenesis of insulin resistance. LPS (lipopolysaccharide)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e1c1106899336db3c934ae49d8acec8
https://doi.org/10.1042/bsr20120098
https://doi.org/10.1042/bsr20120098
Akademický článek
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