Zobrazeno 1 - 10
of 221
pro vyhledávání: '"TINCR"'
Publikováno v:
Acta Pharmaceutica, Vol 74, Iss 1, Pp 131-147 (2024)
There is increasing evidence that long non-coding RNAs (lncRNAs) play a crucial role in the development and progression of malignant tumors, particularly pancreatic cancer. In this study, the influence of the lncRNA TINCR on the behavior of human pan
Externí odkaz:
https://doaj.org/article/2fe68d120c024b6d962c0c4a2461962c
Autor:
Jie Mei, Wenping Lin, Shaohua Li, Yuhao Tang, Zhiwei Ye, Lianghe Lu, Yuhua Wen, Anna Kan, Jingwen Zou, Chengyou Yu, Wei Wei, Rongping Guo
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-15 (2022)
Abstract Background Long non-coding RNAs (lncRNA) have an essential role in progression and chemoresistance of hepatocellular carcinoma (HCC). In-depth study of specific regulatory mechanisms is of great value in providing potential therapeutic targe
Externí odkaz:
https://doaj.org/article/50a0408266f842d8809695a4b88163a4
Autor:
Guoqing He, Rui Pang, Jihua Han, Jinliang Jia, Zhaoming Ding, Wen Bi, Jiawei Yu, Lili Chen, Jiewu Zhang, Yanan Sun
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-16 (2021)
Abstract Background Terminal differentiation-induced ncRNA (TINCR) plays an essential role in epidermal differentiation and is involved in the development of various cancers. Methods qPCR was used to detect the expression level of TINCR in tissues an
Externí odkaz:
https://doaj.org/article/df4a0af797684d759779f175f7a7ad54
Publikováno v:
Cancer Management and Research, Vol Volume 13, Pp 1877-1886 (2021)
Man-Li Zhang, Wei-Wei Liu, Wei-Dong Li Department of Breast Surgery, Cangzhou People’s Hospital, Cangzhou City, 061001, Hebei Province, People’s Republic of ChinaCorrespondence: Man-Li ZhangDepartment of Breast Surgery, Cangzhou People’s Hospit
Externí odkaz:
https://doaj.org/article/41a91868fef4407aa014caf96a1f2102
Publikováno v:
Non-coding RNA Research, Vol 5, Iss 3, Pp 109-115 (2020)
Long non-coding RNAs (lncRNAs) have prominent roles in the pathogenesis of human cancers. Several studies have shown oncogenic or tumor suppressor roles of lncRNAs in different human tissues. Thus, these transcripts have been regarded as putative tar
Externí odkaz:
https://doaj.org/article/93f596dcd28849869b5868f1fac59aee
Publikováno v:
BMC Medical Genetics, Vol 21, Iss 1, Pp 1-6 (2020)
Abstract Background Our preliminary bioinformatics analysis showed that lncRNA TINCR may absorb miR-214-5p by serving is sponge, while miR-214-5p targets ROCK1. This study aimed to investigate the interactions among these 3 factors in hepatocellular
Externí odkaz:
https://doaj.org/article/4b4ff81b1b98480bbb29f9f379ccc004
Akademický článek
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Autor:
Huaying Dong, Jianguo Hu, Kejian Zou, Mulin Ye, Yuanwen Chen, Chengyi Wu, Xin Chen, Mingli Han
Publikováno v:
Molecular Cancer, Vol 18, Iss 1, Pp 1-18 (2019)
Abstract Background Trastuzumab resistance followed by metastasis is a major obstacle for improving the clinical outcome of patients with advanced human epidermal growth factor receptor 2-positive (HER-2+) breast cancer. While long non-coding RNAs (l
Externí odkaz:
https://doaj.org/article/02b39437c66f4c338c7b16014f9d194b
Autor:
Norihito Omote, Koji Sakamoto, Qin Li, Jonas C. Schupp, Taylor Adams, Farida Ahangari, Maurizio Chioccioli, Giuseppe DeIuliis, Naozumi Hashimoto, Yoshinori Hasegawa, Naftali Kaminski
Publikováno v:
Physiological Reports, Vol 9, Iss 3, Pp n/a-n/a (2021)
Abstract Long‐noncoding RNAs (lncRNAs) have numerous biological functions controlling cell differentiation and tissue development. The knowledge about the role of lncRNAs in human lungs remains limited. Here we found the regulatory role of the term
Externí odkaz:
https://doaj.org/article/6491cfd0b47a4840b949550b00034515
Autor:
Zehang Zhuang, Jing Huang, Weiwang Wang, Cheng Wang, Pei Yu, Jing Hu, Haichao Liu, Hanqi Yin, Jinsong Hou, Xiqiang Liu
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
ObjectivesRecently long non-coding RNAs (lncRNAs) have emerged as novel gene regulators involved in tumorigenic processes, including oral squamous cell carcinoma (OSCC). Here, we identified a differentiation-related lncRNA, terminal differentiation-i
Externí odkaz:
https://doaj.org/article/5e62d619471a4719bc03cfe8d3d4abd4