Výsledky vyhledávání - "TIMOTHY D. SMILE"

Akademický článek

Neutrophil to lymphocyte ratio (NTLR) predicts local control and overall survival after stereotactic body radiotherapy (SBRT) in metastatic sarcoma

Autor: Eashwar Somasundaram, Peter M. Anderson, Timothy D. Smile, Ahmed Halima, James B. Broughman, Chandana A. Reddy, Shireen Parsai, Jacob G. Scott, Timothy Chan, Shauna Campbell, Lilyana Angelov, Stacey Zahler, Matteo Trucco, Stefanie M. Thomas, Shavaughn Johnson, Peng Qi, Anthony Magnelli, Erin S. Murphy

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)

Abstract The neutrophil to lymphocyte ratio (NTLR) and absolute lymphocyte count (ALC) recovery are prognostic across many cancers. We investigated whether NLTR predicts SBRT success or survival in a metastatic sarcoma cohort treated with SBRT from 2

Externí odkaz: https://doaj.org/article/a57f16d4409e4815b5102eae2bf44d86

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Immune status does not independently influence cutaneous squamous cell carcinoma metastasis and death when stratified by tumor stage: A dual-center retrospective cohort analysis of primary N0 disease

Autor: Daniel M, O'Connor, Fadi, Murad, Melissa J, Danesh, William, Butler, Timothy D, Smile, Evelyn O, Ilori, Brian R, Gastman, Allison, Vidimos, Abigail B, Waldman, Chrysalyne D, Schmults, Shlomo, Koyfman, Emily S, Ruiz

Publikováno v: Journal of the American Academy of Dermatology. 87:1295-1302

Although immunocompromised patients have a higher risk of developing cutaneous squamous cell carcinomas, it is unknown whether immune status is an independent risk factor for poor outcomes.To compare cutaneous squamous cell carcinoma outcomes in immu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ce062552aed9ad64bfb4045a7cc4c20
https://doi.org/10.1016/j.jaad.2022.08.050

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Identifying Brigham and Women's Hospital stage T2a cutaneous squamous cell carcinomas at risk of poor outcomes

Autor: Neha, Gupta, Rachel E, Weitzman, Fadi, Murad, Shlomo A, Koyfman, Timothy D, Smile, Michael S, Chang, Jacqueline M, Maher, Chrysalyne D, Schmults, Allison T, Vidimos, Emily S, Ruiz

Publikováno v: Journal of the American Academy of Dermatology. 86:1301-1308

Although most of the poor outcomes with cutaneous squamous cell carcinoma (CSCC) occur in high-stage tumors, 26% of nodal metastases and 8% of disease-specific deaths develop in Brigham and Women's Hospital (BWH) T2a tumors.To determine risk factors

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7bdc45190ddcd19592c5fab891fbc04
https://doi.org/10.1016/j.jaad.2021.11.046

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Higher metastasis and death rates in cutaneous squamous cell carcinomas with lymphovascular invasion

Autor: Michael Chang, Evelyn O. Ilori, Emily S. Ruiz, Shlomo A. Koyfman, Guohai Zhou, Fadi Murad, Timothy D. Smile, Sepideh Ashrafzadeh, Allison T. Vidimos, Chrysalyne D. Schmults, Kylee J.B. Kus

Publikováno v: Journal of the American Academy of Dermatology. 86:766-773

Background Lymphovascular invasion (LVI) is an aggressive histologic finding but is excluded from current staging systems due to lack of demonstrated independent prognostic significance. Objective To evaluate the impact of LVI on CSCC tumor outcomes.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d80b0732bb5e3cc1699ca9541b88760
https://doi.org/10.1016/j.jaad.2021.11.002

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Limited Toxicity of Hypofractionated Intensity Modulated Radiation Therapy for Head and Neck Cancer

Autor: Zachary S, Mayo, Evelyn O, Ilori, Brian, Matia, Timothy D, Smile, Christopher W, Fleming, Chandana A, Reddy, Joseph, Scharpf, Eric D, Lamarre, Brandon L, Prendes, Jamie, Ku, Brian B, Burkey, Nikhil P, Joshi, Neil M, Woody, Shlomo A, Koyfman, Shauna R, Campbell

Publikováno v: Anticancer Research. 42:1845-1849

Hypofractionated radiation therapy is not commonly used in head and neck cancers (HNC) due to increased toxicity observed in historical cohorts. This study reviews our institutional experience using hypofractionated intensity modulated radiation ther

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d6be5b856e015a0f1153656072d6bc
https://doi.org/10.21873/anticanres.15660

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125I Interstitial brachytherapy with or without androgen deprivation therapy among unfavorable-intermediate and high-risk prostate cancer

Autor: Rahul D. Tendulkar, James Ulchaker, Chandana A. Reddy, Ahmed Halima, Kenneth Angermeier K, Omar Y. Mian, Eric A. Klein, Jay P. Ciezki, Timothy D. Smile, Steven C. Campbell, Ryan X. Zhang, Kevin L. Stephans, M.C. Tom

Publikováno v: Brachytherapy. 21:85-93

PURPOSE/OBJECTIVE(S) To determine if patients with unfavorable intermediate-risk (UIR), high-risk (HR), or very high-risk (VHR) prostate cancer (PCa) treated with 125I interstitial brachytherapy benefit from androgen deprivation therapy (ADT). MATERI

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8a306c803d8e2fe302aa387830103ea9
https://doi.org/10.1016/j.brachy.2021.09.001

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Implications of Satellitosis or In-transit Metastasis in Cutaneous Squamous Cell Carcinoma: A Prognostic Omission in Cancer Staging Systems

Autor: Timothy D. Smile, Emily S. Ruiz, Kylee J. B. Kus, Fadi Murad, Wei Wei, David D. Xiong, Allison T. Vidimos, Chrysalyne D. Schmults, Shlomo A. Koyfman

Publikováno v: JAMA Dermatol

IMPORTANCE: Unlike Merkel cell carcinoma and melanoma, satellitosis or in-transit metastasis (S-ITM) is not incorporated into the current cutaneous squamous cell carcinoma (CSCC) staging systems. It is important to determine if the clinical outcomes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ae8dc413ba947dcdd8a2a8b9f4fc702
https://pubmed.ncbi.nlm.nih.gov/35195668

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Non-Operative Options for Loco-regional Melanoma

Autor: Timothy D. Smile, Brian R. Gastman, Rebecca Knackstedt, Jennifer S. Yu

Publikováno v: Clinics in Plastic Surgery. 48:631-642

Malignant melanoma is the 5th most common cancer and stage IV melanoma accounts for approximately 4% of new melanoma diagnoses in the United States. The prognosis for regionally advanced disease is poor, but there have been numerous recent advances i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc03ef44c65a8bc1ae625916a20bbc88
https://doi.org/10.1016/j.cps.2021.05.007

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