Zobrazeno 1 - 10
of 66
pro vyhledávání: '"TIFFANY CAZA"'
Autor:
Nick Huang, Thomas Winans, Brandon Wyman, Zachary Oaks, Tamas Faludi, Gourav Choudhary, Zhi-Wei Lai, Joshua Lewis, Miguel Beckford, Manuel Duarte, Daniel Krakko, Akshay Patel, Joy Park, Tiffany Caza, Mahsa Sadeghzadeh, Laurence Morel, Mark Haas, Frank Middleton, Katalin Banki, Andras Perl
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-26 (2024)
Abstract Activation of the mechanistic target of rapamycin (mTOR) is a key metabolic checkpoint of pro-inflammatory T-cell development that contributes to the pathogenesis of autoimmune diseases, such as systemic lupus erythematosus (SLE), however, t
Externí odkaz:
https://doaj.org/article/e3357fd5b886440da3453dab516c3244
Autor:
Naji Alhamid, Bana Sabbagh, Asmaa Alsarraj, Edgar Lerma, Tiffany Caza, Biruh Workeneh, Jacqueline Claudia Barrientos, Kenar D. Jhaveri
Publikováno v:
Kidney & Blood Pressure Research, Pp 1-1 (2024)
Background: Tumor lysis syndrome (TLS) is a well-recognized medical emergency in patients with cancer diagnosis. The diagnostic criteria of TLS have been revised many times since it was recognized, but still have many drawbacks that limit diagnosis a
Externí odkaz:
https://doaj.org/article/ffa6163140174f3a9b62e86a4913152a
Autor:
Angelina Regua, Csaba Papp, Andre Grageda, Baylee A. Porter, Tiffany Caza, Isabelle Bichindaritz, Mira Krendel, Abirami Sivapiragasam, Gennady Bratslavsky, Vladimir A. Kuznetsov, Leszek Kotula
Publikováno v:
Molecular Oncology, Vol 16, Iss 14, Pp 2632-2657 (2022)
Despite the current standard of care, breast cancer remains one of the leading causes of mortality in women worldwide, thus emphasizing the need for better predictive and therapeutic targets. ABI1 is associated with poor survival and an aggressive br
Externí odkaz:
https://doaj.org/article/195f405edb7f4b7589ba1a65f66976c7
Publikováno v:
Kidney International Reports, Vol 7, Iss 3, Pp 618-623 (2022)
Externí odkaz:
https://doaj.org/article/28d1cf358b91485d8b966022b259cb23
Autor:
Ahmad Oussama Rifai, Kristin M. Denig, Tiffany Caza, Shana M. Webb, Sarah Rifai, Sarah Khan, Sally Dahan, Samaa Alamin
Publikováno v:
Case Reports in Nephrology, Vol 2023 (2023)
Antitubular basement membrane (anti-TBM) antibody disease is an extremely rare disorder. It may be idiopathic or secondary to exposure of the proximal tubular basement membrane, triggered by tubular injury due to acute pyelonephritis, acute allergic
Externí odkaz:
https://doaj.org/article/7d255b0240db43fbacf38f364f3ddb65
Publikováno v:
Kidney Medicine, Vol 5, Iss 1, Pp 100575- (2023)
Proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID) is the second most common monoclonal gammopathy of renal significance. Rates of progression to kidney failure as well as rates of recurrence after kidney transplantatio
Externí odkaz:
https://doaj.org/article/75a857cae9b548acbdd0b79343ad4275
Publikováno v:
Kidney Medicine, Vol 4, Iss 12, Pp 100565- (2022)
Externí odkaz:
https://doaj.org/article/3ceb362eab8c4a7ca981efeadf8b4371
Autor:
Disharee Nath, Xiang Li, Claudia Mondragon, Dawn Post, Ming Chen, Julie R. White, Anita Hryniewicz-Jankowska, Tiffany Caza, Vladimir A. Kuznetsov, Heidi Hehnly, Tamara Jamaspishvili, David M. Berman, Fan Zhang, Sonia H. Y. Kung, Ladan Fazli, Martin E. Gleave, Gennady Bratslavsky, Pier Paolo Pandolfi, Leszek Kotula
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-19 (2019)
Abstract Background Prostate cancer development involves various mechanisms, which are poorly understood but pointing to epithelial mesenchymal transition (EMT) as the key mechanism in progression to metastatic disease. ABI1, a member of WAVE complex
Externí odkaz:
https://doaj.org/article/b367179fb38b484e89b1472961698c67
Autor:
Mark R. Woodford, Andrew W. Truman, Diana M. Dunn, Sandra M. Jensen, Richard Cotran, Renee Bullard, Mourad Abouelleil, Kristin Beebe, Donald Wolfgeher, Sara Wierzbicki, Dawn E. Post, Tiffany Caza, Shinji Tsutsumi, Barry Panaretou, Stephen J. Kron, Jane B. Trepel, Steve Landas, Chrisostomos Prodromou, Oleg Shapiro, William G. Stetler-Stevenson, Dimitra Bourboulia, Len Neckers, Gennady Bratslavsky, Mehdi Mollapour
Publikováno v:
Cell Reports, Vol 14, Iss 4, Pp 872-884 (2016)
The molecular chaperone Hsp90 protects deregulated signaling proteins that are vital for tumor growth and survival. Tumors generally display sensitivity and selectivity toward Hsp90 inhibitors; however, the molecular mechanism underlying this phenoty
Externí odkaz:
https://doaj.org/article/94836c555dfb4543879e4bab5562ec97
Autor:
Diana M. Dunn, Mark R. Woodford, Andrew W. Truman, Sandra M. Jensen, Jacqualyn Schulman, Tiffany Caza, Taylor C. Remillard, David Loiselle, Donald Wolfgeher, Brian S.J. Blagg, Lucas Franco, Timothy A. Haystead, Soumya Daturpalli, Matthias P. Mayer, Jane B. Trepel, Rhodri M.L. Morgan, Chrisostomos Prodromou, Stephen J. Kron, Barry Panaretou, William G. Stetler-Stevenson, Steve K. Landas, Len Neckers, Gennady Bratslavsky, Dimitra Bourboulia, Mehdi Mollapour
Publikováno v:
Cell Reports, Vol 12, Iss 6, Pp 1006-1018 (2015)
The ability of Heat Shock Protein 90 (Hsp90) to hydrolyze ATP is essential for its chaperone function. The co-chaperone Aha1 stimulates Hsp90 ATPase activity, tailoring the chaperone function to specific “client” proteins. The intracellular signa
Externí odkaz:
https://doaj.org/article/513261747e0342e1bf436072b173cab8