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Phosphorylation of TRIM28 Enhances the Expression of IFN-β and Proinflammatory Cytokines During HPAIV Infection of Human Lung Epithelial Cells

Autor: Tim Krischuns, Franziska Günl, Lea Henschel, Marco Binder, Joschka Willemsen, Sebastian Schloer, Ursula Rescher, Vanessa Gerlt, Gert Zimmer, Carolin Nordhoff, Stephan Ludwig, Linda Brunotte

Publikováno v: Frontiers in Immunology, Vol 9 (2018)

Human infection with highly pathogenic avian influenza viruses (HPAIV) is often associated with severe tissue damage due to hyperinduction of interferons and proinflammatory cytokines. The reasons for this excessive cytokine expression are still inco

Externí odkaz: https://doaj.org/article/5d889f0f837c463b80d099c80cc2c69c

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Akademický článek

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Akademický článek

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KAP1 is an antiparallel dimer with a functional asymmetry

Autor: Louise C. Bryan, Pierre-Yves Helleboid, Matteo Dal Peraro, Giulia Fonti, Davide Demurtas, Didier Trono, Beat Fierz, Mark D. Tully, Alexandra Styliani Kalantzi, Sergei Grudinin, Sylvain Träger, Maria J. Marcaida

Publikováno v: Life Science Alliance
Life Science Alliance, Life Science Alliance LLC, 2019, 2 (4), pp.e201900349. ⟨10.26508/lsa.201900349⟩
Life Science Alliance, 2019, 2 (4), pp.e201900349. ⟨10.26508/lsa.201900349⟩
'Life Science Alliance ', vol: 2, pages: e201900349-1-e20190034916 (2019)

This study reveals the architecture of human KAP1 by integrating molecular modeling with small-angle X-ray scattering and single-molecule experiments. KAP1 dimers feature a structural asymmetry at the C-terminal domains that has functional implicatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e09bbc8c45778ac53e5b857eee09e6ba
https://hal.archives-ouvertes.fr/hal-02291553

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Phosphorylation of TRIM28 Enhances the Expression of IFN-beta and Proinflammatory Cytokines During HPAIV Infection of Human Lung Epithelial Cells

Autor: Krischuns, T. (Tim), Günl, F. (Franziska), Henschel, L. (Lea), Binder, M. (Marco), Willemsen, J. (Joschka), Schloer, S.M. (Sebastian), Rescher, U. (Ursula), Gerlt, V. (Vanessa), Zimmer, G. (Gert), Nordhoff, C. (Carolin), Ludwig, S. (Stephan), Brunotte, L. (Linda)

Human infection with highly pathogenic avian influenza viruses (HPAIV) is associated with severe tissue damage due to hyperinduction of interferons and proinflammatory cytokines. The reasons for this excessive cytokine expression are still incomplete

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______517::1de3575a214e6a156321874606822938
https://repositorium.uni-muenster.de/transfer/miami/17374ef6-d853-43c1-9f59-ebd39a042709

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Phosphorylation of TRIM28 Enhances the Expression of IFN-β and Proinflammatory Cytokines During HPAIV Infection of Human Lung Epithelial Cells

Autor: Krischuns, Tim, Günl, Franziska, Henschel, Lea, Binder, Marco, Willemsen, Joschka, Schloer, Sebastian, Rescher, Ursula, Gerlt, Vanessa, Zimmer, Gert, Nordhoff, Carolin, Ludwig, Stephan, Brunotte, Linda

Publikováno v: Krischuns, Tim; Günl, Franziska; Henschel, Lea; Binder, Marco; Willemsen, Joschka; Schloer, Sebastian; Rescher, Ursula; Gerlt, Vanessa; Zimmer, Gert; Nordhoff, Carolin; Ludwig, Stephan; Brunotte, Linda (2018). Phosphorylation of TRIM28 Enhances the Expression of IFN-β and Proinflammatory Cytokines During HPAIV Infection of Human Lung Epithelial Cells. Frontiers in immunology, 9, p. 2229. Frontiers Research Foundation 10.3389/fimmu.2018.02229
Frontiers in Immunology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3f4496161bd86ca2713237732abda09
https://boris.unibe.ch/127526/1/fimmu-09-02229.pdf

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