Zobrazeno 1 - 10
of 16
pro vyhledávání: '"TIANLU HOU"'
Publikováno v:
Biomolecules & Biomedicine (2024)
Liver fibrosis is a chronic condition caused by various factors, and currently, there are no widely effective treatments. Autophagy plays a crucial role in maintaining liver energy homeostasis, and its disruption can contribute to the development of
Externí odkaz:
https://doaj.org/article/ac06e052e0714ea7b1324e77d7de2e6a
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-12 (2018)
Abstract Background In this research, we aimed to investigate the biological functions of LIM domain only 3 (LMO3) in hepatocellular carcinoma (HCC) and uncover the underlying molecular mechanism in it. Methods HCC tissue microarray (n = 180) was use
Externí odkaz:
https://doaj.org/article/e4a13cef99d3493eb32ad5751d2b76d9
Publikováno v:
Indian Journal of Pharmaceutical Sciences. May/Jun2024, Vol. 86 Issue 3, p1058-1068. 11p.
Autor:
Yang Cheng1,2, Tianlu Hou2, Jian Ping2, Gaofeng Chen2, Jianjie Chen1,2 Jianjie_chen@hotmail.com
Publikováno v:
Proteome Science. 2/3/2016, Vol. 14, p1-11. 11p.
Publikováno v:
Biochemical and Biophysical Research Communications. 474:57-63
Background and aim Mitochondrial dysfunction plays a major role in critical initiating or propagating events in nonalcoholic fatty liver disease (NAFLD), but its pathogenesis remains obscure. Recently, microRNAs have been found to affect oxidant stre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7c87de6d82ff04793b08e0688dc463e
https://doi.org/10.1016/j.bbrc.2016.04.065
https://doi.org/10.1016/j.bbrc.2016.04.065
Publikováno v:
Journal of cellular physiology.
This study aimed to validate the methylation of key genes in hepatocellular carcinoma (HCC) screened by bioinformatics analysis and explore whether they affected HCC cell proliferation, migration, and invasion. Using The Cancer Genome Atlas (TCGA) da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5ae4e8ce1390bcbe92bdfab30edfe3c
https://pubmed.ncbi.nlm.nih.gov/30779348
https://pubmed.ncbi.nlm.nih.gov/30779348
Figure S1 LMO3 knockdown has no effects on the proliferation of HCC cells. Multiplicity: 1 – single, 2 - multiple; Satelite: 0 – no, 1 or 2 - yes; Encapsulation: 0 – complete, 1 - incomplete; Vascular invasion: 0 – no, 1 - yes; Tumor thrombus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57806029610580ffaa4ca14c14d8fd61
Figure S2 The structure of pGreenPuro used for shRNA and vector construction. (PDF 622 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fdad33b71f387e3e31129d7f2ad791a
Table S2 The original data of tissue microarray assay. (DOC 468 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71cf73842b4c7e2a11a7b46b01c9e010
Table S1 Primer sequences used for human LMO3, CTGF, ANKRD1 and CYR61 detection. a Edu assay of MHCC-97H cells infected with siRNA of LMO3 at 0, 24, 48 and 72 h time points respectively. b Edu assay of SMMC-7721 cells infected with siRNA of LMO3 at 0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb43c9d413088b3f6746322e196b295d