Zobrazeno 1 - 10
of 64
pro vyhledávání: '"THOMAS OLSSON BONTELL"'
Autor:
Elizabeth Schepke, Maja Löfgren, Torsten Pietsch, Teresia Kling, Claes Nordborg, Thomas Olsson Bontell, Stefan Holm, Anders Öberg, Per Nyman, Marie Eliasson-Hofvander, Magnus Sabel, Birgitta Lannering, Helena Carén
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-11 (2023)
Abstract Background Molecular analyses have shown that tumours diagnosed as supratentorial primitive neuro-ectodermal tumours of the central nervous system (CNS-PNETs) in the past represent a heterogenous group of rare childhood tumours including hig
Externí odkaz:
https://doaj.org/article/7e189eae54f44ad29c3940924f6752ee
Autor:
Sandra Ferreyra Vega, Thomas Olsson Bontell, Teresia Kling, Asgeir Store Jakola, Helena Carén
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-14 (2023)
Abstract Diffuse gliomas are the most prevalent malignant primary brain tumors in adults and remain incurable despite standard therapy. Tumor recurrence is currently inevitable, which contributes to a persistent high morbidity and mortality in these
Externí odkaz:
https://doaj.org/article/b2c3c4bc057643f99422e07e4d0768af
Autor:
Anna Wenger, Sandra Ferreyra Vega, Elizabeth Schepke, Maja Löfgren, Thomas Olsson Bontell, Magnus Tisell, Daniel Nilsson, Teresia Kling, Helena Carén
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-14 (2022)
Abstract DNA methylation is increasingly used for tumour classification and has expanded upon the > 100 currently known brain tumour entities. A correct diagnosis is the basis for suitable treatment for patients with brain tumours, which is the leadi
Externí odkaz:
https://doaj.org/article/314bf8a820aa4c669a7178991cf1a55a
Autor:
Olivia Näslund, Anna Lipatnikova, Anna Dénes, Cecilia Lindskog, Thomas Olsson Bontell, Anja Smits, Asgeir S. Jakola, Alba Corell
Publikováno v:
Brain and Spine, Vol 3, Iss , Pp 101711- (2023)
Introduction: Meningiomas account for nearly 40% of intracranial tumors. Recently, the immunohistochemistry (IHC) markers S100B, SCGN, ACADL and MCM2 have been shown to be associated with underlying biological subtypes of meningioma (MG1-MG4). We aim
Externí odkaz:
https://doaj.org/article/3526948f62164cc3891252fd2ef9d639
Autor:
Anna Dénes, Thomas Olsson Bontell, Hanna Barchéus, Sandra Ferreyra Vega, Helena Carén, Cecilia Lindskog, Asgeir S Jakola, Anja Smits
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0285732 (2023)
ObjectivesAccumulating evidence shows that mesenchymal transition of glioblastomas is associated with a more aggressive course of disease and therapy resistance. In WHO2021-defined adult-type diffuse gliomas of lower grade (dLGG), the transition of t
Externí odkaz:
https://doaj.org/article/7e8788669dd04c39805edf7ebf5571e8
Autor:
Luuk van Hooren, Alessandra Vaccaro, Mohanraj Ramachandran, Konstantinos Vazaios, Sylwia Libard, Tiarne van de Walle, Maria Georganaki, Hua Huang, Ilkka Pietilä, Joey Lau, Maria H. Ulvmar, Mikael C. I. Karlsson, Maria Zetterling, Sara M. Mangsbo, Asgeir S. Jakola, Thomas Olsson Bontell, Anja Smits, Magnus Essand, Anna Dimberg
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Agonistic CD40 antibodies (αCD40) have broad immunostimulatory properties, however their efficacy in glioma remains unclear. Here the authors show that αCD40 promotes the formation of tertiary lymphoid structures but does not improve survival and i
Externí odkaz:
https://doaj.org/article/960c23767579410eb75556847b8c9b3f
Autor:
Alba Corell, Sandra Ferreyra Vega, Nickoleta Hoefling, Louise Carstam, Anja Smits, Thomas Olsson Bontell, Isabella M. Björkman-Burtscher, Helena Carén, Asgeir Store Jakola
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background The T2-FLAIR mismatch sign is an imaging finding highly suggestive of isocitrate dehydrogenase mutated (IDH-mut) 1p19q non-codeleted (non-codel) gliomas (astrocytomas). In previous studies, it has shown excellent specificity but l
Externí odkaz:
https://doaj.org/article/0105ed9f440244b5ab9d752e85ca5bc7
Autor:
Louise Carstam, Alba Corell, Anja Smits, Anna Dénes, Hanna Barchéus, Klara Modin, Helene Sjögren, Sandra Ferreyra Vega, Thomas Olsson Bontell, Helena Carén, Asgeir Store Jakola
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
BackgroundWhile molecular insights to diffuse lower-grade glioma (dLGG) have improved the basis for prognostication, most established clinical prognostic factors come from the pre-molecular era. For instance, WHO grade as a predictor for survival in
Externí odkaz:
https://doaj.org/article/93b1dcdc11f644caa6798c282abd1682
Autor:
Julia Izsak, Dzeneta Vizlin-Hodzic, Margarita Iljin, Joakim Strandberg, Janusz Jadasz, Thomas Olsson Bontell, Stephan Theiss, Eric Hanse, Hans Ågren, Keiko Funa, Sebastian Illes
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Persistent neural stem cell (NSC) proliferation is, among others, a hallmark of immaturity in human induced pluripotent stem cell (hiPSC)-based neural models. TGF-β1 is known to regulate NSCs in vivo during embryonic development in rodents. Here we
Externí odkaz:
https://doaj.org/article/66d945539ed34be099807ded70c1bc61
Autor:
Mohanraj Ramachandran, Alessandra Vaccaro, Tiarne van de Walle, Maria Georganaki, Roberta Lugano, Kalyani Vemuri, Despoina Kourougkiaouri, Konstantinos Vazaios, Marie Hedlund, Georgia Tsaridou, Lene Uhrbom, Ilkka Pietilä, Miika Martikainen, Luuk van Hooren, Thomas Olsson Bontell, Asgeir S. Jakola, Di Yu, Bengt Westermark, Magnus Essand, Anna Dimberg
Publikováno v:
Cancer Cell.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fac666d92e89c1d9cb950afcd918920
https://doi.org/10.1016/j.ccell.2023.04.010
https://doi.org/10.1016/j.ccell.2023.04.010