Zobrazeno 1 - 10
of 83
pro vyhledávání: '"THIERRY SULPICE"'
Autor:
Maxime Nachit, Christopher Montemagno, Romain Clerc, Mitra Ahmadi, François Briand, Sandrine Bacot, Nick Devoogdt, Cindy Serdjebi, Catherine Ghezzi, Thierry Sulpice, Alexis Broisat, Isabelle A. Leclercq, Pascale Perret
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Here, the authors present a noninvasive tool to detect liver inflammation using nuclear imaging, as an alternative to biopsy. The prove the diagnostic power of this tool to detect liver inflammation in preclinical models of chronic liver disease.
Externí odkaz:
https://doaj.org/article/d88758d761954f49a5f4a5060910e50c
Autor:
Clement Karsenty, Celine Guilbeau-Frugier, Gaël Genet, Marie-Helene Seguelas, Philippe Alzieu, Olivier Cazorla, Alexandra Montagner, Yuna Blum, Caroline Dubroca, Julile Maupoint, Blandine Tramunt, Marie Cauquil, Thierry Sulpice, Sylvain Richard, Silvia Arcucci, Remy Flores-Flores, Nicolas Pataluch, Romain Montoriol, Pierre Sicard, Antoine Deney, Thierry Couffinhal, Jean-Michel Senard, Celine Galés
Publikováno v:
eLife, Vol 12 (2023)
The rod-shaped adult cardiomyocyte (CM) harbors a unique architecture of its lateral surface with periodic crests, relying on the presence of subsarcolemmal mitochondria (SSM) with unknown role. Here, we investigated the development and functional ro
Externí odkaz:
https://doaj.org/article/4a1c47633a1c414d92ff3c8bf4e59cf3
Autor:
Valentin Sencio, Arnaud Machelart, Cyril Robil, Nicolas Benech, Eik Hoffmann, Chloé Galbert, Lucie Deryuter, Séverine Heumel, Aline Hantute-Ghesquier, Anne Flourens, Priscille Brodin, Fabrice Infanti, Virgile Richard, Jean Dubuisson, Corinne Grangette, Thierry Sulpice, Isabelle Wolowczuk, Florence Pinet, Vincent Prévot, Sandrine Belouzard, François Briand, Martine Duterque-Coquillaud, Harry Sokol, François Trottein
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Mounting evidence suggests that the gut-to-lung axis is critical during respiratory viral infections. We herein hypothesized that disruption of gut homeostasis during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may associat
Externí odkaz:
https://doaj.org/article/550d4d66dfae45ffb125630022a5aad4
Autor:
Valentin Sencio, Nicolas Benech, Cyril Robil, Lucie Deruyter, Séverine Heumel, Arnaud Machelart, Thierry Sulpice, Antonin Lamazière, Corinne Grangette, François Briand, Harry Sokol, François Trottein
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Obese patientss with nonalcoholic steatohepatitis (NASH) are particularly prone to developing severe forms of coronavirus disease 19 (COVID-19). The gut-to-lung axis is critical during viral infections of the respiratory tract, and a change in the gu
Externí odkaz:
https://doaj.org/article/a5f3a88364964b48ab00ce67879bbede
Publikováno v:
Dose-Response, Vol 20 (2022)
Background Nitric oxide (NO) as a vaso- and cardio-protective agent could reduce vasomotor dysfunction in different cardiovascular diseases. One of the current therapeutics targeted at NO availability in the vascular wall are highly diluted antibodie
Externí odkaz:
https://doaj.org/article/cf67d46ecce94d3e83647a37ed8896e0
Autor:
François Briand, Christophe Heymes, Lucile Bonada, Thibault Angles, Julie Charpentier, Maxime Branchereau, Emmanuel Brousseau, Marjolaine Quinsat, Nicolas Fazilleau, Rémy Burcelin, Thierry Sulpice
Publikováno v:
Clinical and Translational Science, Vol 13, Iss 3, Pp 529-538 (2020)
The long duration of animal models represents a clear limitation to quickly evaluate the efficacy of drugs targeting nonalcoholic steatohepatitis (NASH). We, therefore, developed a rapid mouse model of liver inflammation (i.e., the mouse fed a high
Externí odkaz:
https://doaj.org/article/5f2062577a4c4bb8ad38095fecb2a6ca
Autor:
François Briand, Valentin Sencio, Cyril Robil, Séverine Heumel, Lucie Deruyter, Arnaud Machelart, Johanna Barthelemy, Gemma Bogard, Eik Hoffmann, Fabrice Infanti, Oliver Domenig, Audrey Chabrat, Virgile Richard, Vincent Prévot, Ruben Nogueiras, Isabelle Wolowczuk, Florence Pinet, Thierry Sulpice, François Trottein
Publikováno v:
Viruses, Vol 14, Iss 9, p 2067 (2022)
Obese patients with non-alcoholic steatohepatitis (NASH) are prone to severe forms of COVID-19. There is an urgent need for new treatments that lower the severity of COVID-19 in this vulnerable population. To better replicate the human context, we se
Externí odkaz:
https://doaj.org/article/e0f3dac631bc44eea379559d5efb400a
Autor:
Jose Castro-Perez, François Briand, Karen Gagen, Sheng-Ping Wang, Ying Chen, David G. McLaren, Vinit Shah, Rob J. Vreeken, Thomas Hankemeier, Thierry Sulpice, Thomas P. Roddy, Brian K. Hubbard, Douglas G. Johns
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 11, Pp 1965-1973 (2011)
Cholesteryl ester transfer protein (CETP) transfers cholesteryl ester (CE) and triglyceride between HDL and apoB-containing lipoproteins. Anacetrapib (ANA), a reversible inhibitor of CETP, raises HDL cholesterol (HDL-C) and lowers LDL cholesterol in
Externí odkaz:
https://doaj.org/article/83541afcd8634ff88cfe29d2ff63b5d4
Autor:
François Briand, Morgan Tréguier, Agnès André, Didier Grillot, Marc Issandou, Khadija Ouguerram, Thierry Sulpice
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 4, Pp 763-770 (2010)
Liver X receptor (LXR) activation promotes reverse cholesterol transport (RCT) in rodents but has major side effects (increased triglycerides and LDL-cholesterol levels) in species expressing cholesteryl ester transfer protein (CETP). In the face of
Externí odkaz:
https://doaj.org/article/f76eb481b98d44298bd7f909cd523ecf
Autor:
Emilie Pepin, Arisa Higa, Carole Schuster-Klein, Catherine Bernard, Thierry Sulpice, Beatrice Guardiola, Eric Chevet, Thierry Alquier
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112714 (2014)
BACKGROUND:Type 2 diabetes is characterized by pancreatic beta-cell dysfunction and is associated with low-grade inflammation. Recent observations suggest that apoptosis signal-regulating kinase 1 (ASK1) is involved in beta-cell death in response to
Externí odkaz:
https://doaj.org/article/644537aa8f6c42fe93c96b3c18b4577a