Výsledky vyhledávání - "THIAGARAJAN GANESH"

Akademický článek

Osteocyte Wnt/β-catenin pathway activation upon mechanical loading is altered in ovariectomized mice

Autor: Erica Jackson, Nuria Lara-Castillo, Mohammed P. Akhter, Mark Dallas, JoAnna M. Scott, Thiagarajan Ganesh, Mark L. Johnson

Publikováno v: Bone Reports, Vol 15, Iss , Pp 101129- (2021)

Estrogen levels decline in both sexes with age, but more dramatically in females. Activation of the Wnt/β-catenin signaling pathway is central to the regulation of bone mass accrual and maintenance and in response to mechanical loading. Using the ov

Externí odkaz: https://doaj.org/article/2a032dfe8d8b4b2d88b9ef33de850cf2

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Akademický článek

Autor: Hammad Mumtaz, Mark Dallas, Mark Begonia, Nuria Lara-Castillo, JoAnna M. Scott, Mark L. Johnson, Thiagarajan Ganesh

Publikováno v: Bone Reports, Vol 12, Iss , Pp 100266- (2020)

Aging is known to reduce bone quality and bone strength. We sought to determine how aging affects the biomechanical and architectural properties of various long bones, and if sex influences age related differences/changes. While researchers have exte

Externí odkaz: https://doaj.org/article/62869c1cbc7244288b4aa9b2c84c0c6f

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Akademický článek

Osteocyte lacunar strain determination using multiscale finite element analysis

Autor: Sravan K. Kola, Mark T. Begonia, LeAnn M. Tiede-Lewis, Loretta E. Laughrey, Sarah L. Dallas, Mark L. Johnson, Thiagarajan Ganesh

Publikováno v: Bone Reports, Vol 12, Iss , Pp 100277- (2020)

Osteocytes are thought to be the primary mechanosensory cells within bone, regulating both osteoclasts and osteoblasts to control load induced changes in bone resorption and formation. Osteocytes initiate intracellular responses including activating

Externí odkaz: https://doaj.org/article/6804220407664fdbae8e16a44d4b539e

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