Zobrazeno 1 - 10
of 139
pro vyhledávání: '"THF, tetrahydrofuran"'
Publikováno v:
Energy Reports, Vol 8, Iss , Pp 735-748 (2022)
Solubility between ethanol and diesel impedes the application of ethanol in diesel engines. The objective of the experiment is to compare combustion and emission characteristics of ethanol/diesel fuels using biodiesel, n-pentanol, tetrahydrofuran (TH
Externí odkaz:
https://doaj.org/article/932247063a3d47dc947bf08b5503050a
Weathering Effect on Surface Characteristics of Superhydrophobic/ Hydrophobic Nanocomposites Coating
Autor:
Hassan Jaafar, Balqees Aldabbagh
Publikováno v:
Engineering and Technology Journal, Vol 37, Iss 3B, Pp 92-98 (2019)
Superhydrophobic and hydrophobic nanocomposites coating synthesized by electrospinning, polymer solution of (PS/DMF, PMMA/THF and Si/Th) were prepared in different wt% of composition for each solutions and also prepared with addition of TiO2 nanopart
Externí odkaz:
https://doaj.org/article/96fb448dedac4429b217d3a0899c8ea3
Autor:
Huihui Zou, Zheng Wei, Chuanhui Song, Yu Cai, Sheng Chen, Gongyuan Liu, Wei Han, Jianchuan Ran, Xiteng Yin, Yufeng Wang, Chuanchao Tang, Guorong Zhang
Publikováno v:
Bioactive Materials, Vol 6, Iss 7, Pp 2144-2157 (2021)
Bioactive Materials
Bioactive Materials
Here, evodiamine (EVO) and the photosensitizer indocyanine green (ICG) were integrated into a liposomal nanoplatform for noninvasive diagnostic imaging and combinatorial therapy against oral squamous cell carcinoma (OSCC). EVO, as an active component
Autor:
Tiantian Qi, Letian Zhang, Tingyuan Yang, Yating Luo, Shiliang Li, Fanxun Zeng, Lili Zhu, Guantian Yang, Yingfan Liang, Honglin Li, Rui Wang, Xiaoyong Xu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 795-809 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Human dihydroorotate dehydrogenase (DHODH) is a viable target for the development of therapeutics to treat cancer and immunological diseases, such as rheumatoid arthritis (RA), psoriasis and multiple sclerosis (MS). Herein, a series of acrylamide-bas
Autor:
Jia Meng, Yan Zhao, Guangying Shao, Shun Zhang, Zemei Ge, Baoxue Yang, Xiaoqiang Geng, Shuyuan Wang, Yue Xu, Min Li, Jinzhao He, Runtao Li, Guangping Chen, Hong Zhou, Jianhua Ran
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 1, Pp 181-202 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Urea transporters (UT) play a vital role in the mechanism of urine concentration and are recognized as novel targets for the development of salt-sparing diuretics. Thus, UT inhibitors are promising for development as novel diuretics. In the present s
Autor:
Xin-Hui Zhang, Hong-Min Liu, Yongfang Yao, Li-Ying Ma, Xue-Jian Feng, Qin Shangshang, Tingting Yu, Bing Zhao, De-Quan Yu, Xiaoling Zhang, Ying Liu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 1, Pp 203-221 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
New Delhi metallo-β-lactamase-1 (NDM-1) is capable of hydrolyzing nearly all β-lactam antibiotics, posing an emerging threat to public health. There are currently less effective treatment options for treating NDM-1 positive “superbug”, and no p
Autor:
Lupei Du, Xiaodong Shi, Yuxing Lin, Xiaojun Qin, Minyong Li, Hui Song, Xiang Li, Zheng Zhang, Gaopan Dong, Zhongxia Yu, Wei Zhao, Zhenzhen Li
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 9, Pp 1669-1679 (2020)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Proteolysis targeting chimeras (PROTACs) are dual-functional hybrid molecules that can selectively recruit an E3 ubiquitin ligase to a target protein to direct the protein into the ubiquitin-proteasome system (UPS), thereby selectively reducing the t
Akademický článek
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Autor:
Dhanya Raveendra-Panickar, Darren Finlay, Fabiana Izidro Layng, Lester J. Lambert, Maria Celeridad, Ming Zhao, Karina Barbosa, Laurent J.S. De Backer, Elizabeth Kwong, Palak Gosalia, Socorro Rodiles, John Holleran, Robert Ardecky, Stefan Grotegut, Steven Olson, John H. Hutchinson, Elena B. Pasquale, Kristiina Vuori, Aniruddha J. Deshpande, Nicholas D.P. Cosford, Lutz Tautz
Publikováno v:
The Journal of Biological Chemistry
Disturbance of the dynamic balance between tyrosine phosphorylation and dephosphorylation of signaling molecules, controlled by protein tyrosine kinases and protein tyrosine phosphatases (PTPs), is known to lead to the development of cancer. While mo
Autor:
Katlin B. Massirer, Lewis E. Pennicott, Fiona Scott, Jonathan M. Elkins, Simon E. Ward, Tristan Reuillon, A.M. Fala
Publikováno v:
Bioorganic & Medicinal Chemistry Letters
Graphical abstract
Kinases are signalling proteins which have proven to be successful targets for the treatment of a variety of diseases, predominantly in cancers. However, only a small proportion of kinases (
Kinases are signalling proteins which have proven to be successful targets for the treatment of a variety of diseases, predominantly in cancers. However, only a small proportion of kinases (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee1561d0a57fd94895c128a26cfe5805
https://doi.org/10.1016/j.bmcl.2020.127040
https://doi.org/10.1016/j.bmcl.2020.127040