Zobrazeno 1 - 10
of 30
pro vyhledávání: '"THERESA V. ROHM"'
Autor:
Angela J. T. Bosch, Theresa V. Rohm, Shefaa AlAsfoor, Andy J. Y. Low, Zora Baumann, Neena Parayil, Faiza Noreen, Julien Roux, Daniel T. Meier, Claudia Cavelti-Weder
Publikováno v:
Particle and Fibre Toxicology, Vol 20, Iss 1, Pp 1-16 (2023)
Abstract Background We previously found that air pollution particles reaching the gastrointestinal tract elicit gut inflammation as shown by up-regulated gene expression of pro-inflammatory cytokines and monocyte/macrophage markers. This inflammatory
Externí odkaz:
https://doaj.org/article/bb847b6aea4a4d6d8971b636af85b7af
Autor:
Angela J. T. Bosch, Theresa V. Rohm, Shefaa AlAsfoor, Andy J. Y. Low, Lena Keller, Zora Baumann, Neena Parayil, Marc Stawiski, Leila Rachid, Thomas Dervos, Sandra Mitrovic, Daniel T. Meier, Claudia Cavelti-Weder
Publikováno v:
Particle and Fibre Toxicology, Vol 20, Iss 1, Pp 1-15 (2023)
Abstract Background Air pollution has emerged as an unexpected risk factor for diabetes. However, the mechanism behind remains ill-defined. So far, the lung has been considered as the main target organ of air pollution. In contrast, the gut has recei
Externí odkaz:
https://doaj.org/article/69c058265092496881f3beb53d3725e0
Autor:
Theresa V. Rohm, Lena Keller, Angela J. T. Bosch, Shefaa AlAsfoor, Zora Baumann, Amandine Thomas, Sophia J. Wiedemann, Laura Steiger, Elise Dalmas, Josua Wehner, Leila Rachid, Catherine Mooser, Bahtiyar Yilmaz, Nerea Fernandez Trigo, Annaise J. Jauch, Stephan Wueest, Daniel Konrad, Sandrine Henri, Jan H. Niess, Petr Hruz, Stephanie C. Ganal-Vonarburg, Julien Roux, Daniel T. Meier, Claudia Cavelti-Weder
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Expansion of pro-inflammatory macrophages in the colon occurs early after high-fat diet initiation, prior to macrophage accumulation in the adipose tissue, in a microbiome-dependent fashion. Macrophage depletion systemically and/or exclusively in the
Externí odkaz:
https://doaj.org/article/80b59b6deb3e496981cc210ada5bc2b9
Autor:
Theresa V. Rohm, Regula Fuchs, Rahel L. Müller, Lena Keller, Zora Baumann, Angela J. T. Bosch, Romano Schneider, Danny Labes, Igor Langer, Julia B. Pilz, Jan H. Niess, Tarik Delko, Petr Hruz, Claudia Cavelti-Weder
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Chronic low-grade inflammation is a hallmark of obesity and associated with cardiovascular complications. However, it remains unclear where this inflammation starts. As the gut is constantly exposed to food, gut microbiota, and metabolites, we hypoth
Externí odkaz:
https://doaj.org/article/68d2126e735c4cd591fb7be215bd03aa
Autor:
THERESA V. ROHM, FELIPE C.G. REIS, ROI ISAAC, MILES PASZEK, GAUTAM BANDYOPADHYAY, JERROLD M. OLEFSKY
Publikováno v:
Diabetes. 71
Background: The beneficial metabolic effects of the PPARγ agonist rosiglitazone (Rosi) are associated with anti-inflammatory changes in adipose tissue macrophages (ATMs) . One study aim was to characterize the in vivo Rosi-induced phenotypic switch
Autor:
Romano Schneider, Marko Kraljević, Ralph Peterli, Theresa V. Rohm, Angela J.T. Bosch, Andy J.Y. Low, Lena Keller, Shefaa AlAsfoor, Simon Häfliger, Bahtiyar Yilmaz, Caspar J. Peterson, Ioannis I. Lazaridis, Pascale Vonaesch, Tarik Delko, Claudia Cavelti-Weder
BACKGROUND Roux-en-Y gastric bypass (RYGB) results in long-term weight loss and reduced obesity related co-morbidities. However, little is known about how the lengths of the biliopancreatic limb (BPL), the alimentary limb (AL), and the common limb (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e3f8a5195169d568a15f3e756a317ae
Publikováno v:
Immunity
Obesity leads to chronic, systemic inflammation and can lead to insulin resistance (IR), β-cell dysfunction, and ultimately type 2 diabetes (T2D). This chronic inflammatory state contributes to long-term complications of diabetes, including non-alco
Autor:
Theresa V. Rohm, Romano Schneider, Claudia Cavelti-Weder, A J Y Low, Marko Kraljević, C J Peterson, P Vonaesch, Ioannis Lazaridis, Tarik Delko, Ralph Peterli, Angela J.T. Bosch
Publikováno v:
British Journal of Surgery. 108
Objective Roux-en-Y gastric bypass (RYGB) shows durable long-term weight loss and control of comorbidities in randomized controlled trials. However, the impact of the proportions of the biliopancreatic limb (BPL) and the total alimentary limb (TALL)
Autor:
Romano Schneider, Theresa V. Rohm, Danny Labes, Zora Baumann, Lena Keller, Regula Fuchs, Claudia Cavelti-Weder
Publikováno v:
Diabetes. 69
Background: Our previous studies in mice showed that high fat diet leads to a pro-inflammatory phenotype of intestinal macrophages. Colon-specific depletion of intestinal macrophages led to improved glycemic control, suggesting a causal link between
Autor:
Kelly Trimigliozzi, Marianne Boeni-Schnetzler, Daniel T. Meier, Erez Dror, Sophia J. Wiedemann, Theresa V. Rohm, Friederike Schulze, Jose Alberto Molina-Tijeras, Hélène Méreau, Marc Y. Donath, Leila Rachid, Christophe Magnan, Stéphanie P. Häuselmann
Publikováno v:
Diabetes. 69
The non-glucose dependent spike in insulin levels immediately following the beginning of a meal is called the cephalic or pre-absorptive phase of insulin secretion. Even though this early insulin response is of marked consequence for overall postpran