Zobrazeno 1 - 10
of 7 133
pro vyhledávání: '"THERAPEUTIC STRATEGY"'
Autor:
Ling Wang, Xiaoyan Zhang, Ziyi Yang, Binquan Wang, Hongyang Gong, Ke Zhang, Yi Lin, Mingkuan Sun
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-25 (2024)
Abstract Extracellular vesicles (EVs) are membrane vesicles originating from different cells within the brain. The pathophysiological role of EVs in neurodegenerative diseases is progressively acknowledged. This field has advanced from basic biologic
Externí odkaz:
https://doaj.org/article/7e3b13457842468cb6b60a5a7ed557ff
Autor:
Zhao Jinyu, Yue Ping, Mi Ningning, Li Matu, Fu Wenkang, Zhang Xianzhuo, Gao Long, Bai Mingzhen, Tian Liang, Jiang Ningzu, Lu Yawen, Ma Haidong, Dong Chunlu, Zhang Yong, Zhang Hengwei, Zhang Jinduo, Ren Yanxian, Suzuki Azumi, Wong Peng F., Tanaka Kiyohito, Rerknimitr Rungsun, Junger Henrik H., Cheung Tan T., Melloul Emmanuel, Demartines Nicolas, Leung Joseph W., Yao Jia, Yuan Jinqiu, Lin Yanyan, Schlitt Hans J., Meng Wenbo
Publikováno v:
Medical Review, Vol 4, Iss 4, Pp 326-365 (2024)
Fibrosis resulting from pathological repair secondary to recurrent or persistent tissue damage often leads to organ failure and mortality. Biliary fibrosis is a crucial but easily neglected pathological feature in hepatobiliary disorders, which may p
Externí odkaz:
https://doaj.org/article/f00ec880e3164f95b5225644f4d94ec7
Autor:
Xiang Yao, Hongyuan Liu, Yuxuan Ma, Minjie Hu, Chong Wang, Han Miao, ShengJie Liu, Jilei Tang
Publikováno v:
Orthopaedic Surgery, Vol 16, Iss 8, Pp 1903-1911 (2024)
Objectives Tibial tubercle is a crucial player in maintaining the structural integrity and functional stability of the knee joint. Currently, there is no standardized protocol for the classification and treatment of tibial tubercle fractures in adult
Externí odkaz:
https://doaj.org/article/a49672bd797146afb63ac87efbb3c05a
Autor:
Jincai Zhou, Bixia Lei, Feifei Shi, Xinran Luo, Kai Wu, Yanhong Xu, Yuting Zhang, Rongjiao Liu, Huajing Wang, Joy Zhou, Xiaowen He
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Systemic lupus erythematosus (SLE) and lupus nephritis (LN) are debilitating autoimmune disorders characterized by pathological autoantibodies production and immune dysfunction, causing chronic inflammation and multi-organ damage. Despite current tre
Externí odkaz:
https://doaj.org/article/719331ff101a42578b476c2e98da5762
Autor:
Masayoshi Sakano, Yoshinobu Tomita, Takumi Kanazawa, Sachiko Ishibashi, Masumi Ikeda, Haruna Oshita, Yuri Hananoi, Yuki Kato, Kurara Yamamoto, Asuka Furukawa, Mayumi Kinoshita, Shigeo Haruki, Masanori Tokunaga, Yusuke Kinugasa, Morito Kurata, Masanobu Kitagawa, Kenichi Ohashi, Kouhei Yamamoto
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundEsophageal cancer, particularly esophageal squamous cell carcinoma (ESCC), is a leading cause of cancer-related death and has a poor prognosis. Despite the advancements in multidisciplinary therapies, resistance to conventional treatments w
Externí odkaz:
https://doaj.org/article/cd2cd7d9e92c4ce7b152fd96edae82ec
Publikováno v:
Annals of Medicine, Vol 56, Iss 1 (2024)
Aim This review aims to summarize the epidemiology, etiology, pathogenesis, clinical manifestations, and current diagnostic and therapeutic approaches for mucormycosis. The goal is to improve understanding of mucormycosis and promote early diagnosis
Externí odkaz:
https://doaj.org/article/2814a54c190048e59c90bbd2024c6b3a
Publikováno v:
International Journal of Hyperthermia, Vol 41, Iss 1 (2024)
Background Microwave ablation (MWA) is a widely adopted treatment technique for hepatocellular carcinoma (HCC). However, MWA alone is of limited use and has a high recurrence rate. Transforming growth factor-β1 (TGF-β1) is recognized as a potential
Externí odkaz:
https://doaj.org/article/b601515220c5482bb477f8aed5b6d4a9
Autor:
Xiao Hong, Shuo Huang, He Jiang, Qing Ma, Jiang Qiu, Qihan Luo, Chunlu Cao, Yiyang Xu, Fuzhe Chen, Yufan Chen, Chunfeng Sun, Haozhe Fu, Yiming Liu, Changyu Li, Fangming Chen, Ping Qiu
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Alcohol-related liver disease (ALD) is a major cause of morbidity and mortality worldwide. It encompasses conditions such as fatty liver, alcoholic hepatitis, chronic hepatitis with liver fibrosis or cirrhosis, and hepatocellular carcinoma. Numerous
Externí odkaz:
https://doaj.org/article/671edd11443141f9ad5bd0c651f6c7ed
Autor:
Yuxuan He, Jingyi Wang, Chunmiao Ying, Kang Li Xu, Jingwen Luo, Baiqiao Wang, Jing Gao, Zaitian Yin, Yunke Zhang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Stroke ranks as the second most significant contributor to mortality worldwide and is a major factor in disability. Ischemic strokes account for 71% of all stroke incidences globally. The foremost approach to treating ischemic stroke prioritizes quic
Externí odkaz:
https://doaj.org/article/045e93ee18e34a3cb792a81188c59c88
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Hepatocellular carcinoma (HCC), an aggressive malignancy with a dismal prognosis, poses a significant public health challenge. Recent research has highlighted the crucial role of lipid metabolism in HCC development, with enhanced lipid synth
Externí odkaz:
https://doaj.org/article/64ea9247b2f2407f92af95d24edf84da