Zobrazeno 1 - 10
of 101
pro vyhledávání: '"TH, Tyrosine hydroxylase"'
Autor:
Yilin Wang, Chunmei Wang, Meiyan Liu, Wuhen Xu, Simei Wang, Fang Yuan, Xiaona Luo, Quanmei Xu, Rongrong Yin, Anqi Wang, Miao Guo, Longlong Lin, Chao Wang, Hongyi Cheng, Zhiping Liu, Yuanfeng Zhang, Fanyi Zeng, Jingbin Yan, Yucai Chen
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Dopa-responsive dystonia (DRD), also known as Segawa syndrome, is a rare neurotransmitter disease. The decrease in dopamine caused by tyrosine hydroxylase (TH) gene mutation may lead to dystonia, tremor and severe encephalopathy in children. Although
Externí odkaz:
https://doaj.org/article/b4c72c20fa7b4310acb4c5086f031a5c
Publikováno v:
Biomolecules; Volume 13; Issue 1; Pages: 51
The G2019S mutation in the leucine-rich repeat kinase 2 (LRRK2) gene is associated with late-onset Parkinson’s disease (PD). Although PD affects men and women differently, longitudinal studies examining sex- and age-dependent alterations in mice ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::48087f6f72c7023e4de51552e88c65b3
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 5348-5359 (2021)
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal
Graphical abstract
Alpha-synuclein (αSyn) is often described as a predominantly disordered protein that has a propensity to self-assemble into toxic oligomers that are found in patients with Parkinson's and Alzheimer's diseases. αSyn's chapero
Alpha-synuclein (αSyn) is often described as a predominantly disordered protein that has a propensity to self-assemble into toxic oligomers that are found in patients with Parkinson's and Alzheimer's diseases. αSyn's chapero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f3815ae5a59c507002487ccf613576d
https://doi.org/10.1016/j.csbj.2021.09.011
https://doi.org/10.1016/j.csbj.2021.09.011
Autor:
A. Cota-Coronado, O.R. Hernández-Pérez, Néstor F. Díaz, Pavel H. Lugo-Fabres, N. Emmanuel Díaz-Martínez, Valeria Valadez-Barba, Eduardo Padilla-Camberos
Publikováno v:
Regenerative Therapy, Vol 15, Iss, Pp 332-339 (2020)
Regenerative Therapy
Regenerative Therapy
Neurodegenerative disorders such as Parkinson's and Alzheimer's disease, are fundamental health concerns all around the world. The development of novel treatments and new techniques to address these disorders, are being actively studied by researcher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5533df458e5d5b5603371b246a30631c
http://www.sciencedirect.com/science/article/pii/S2352320420300894
http://www.sciencedirect.com/science/article/pii/S2352320420300894
'Effect of valerenic acid on neuroinflammation in a MPTP-induced mouse model of Parkinson’s disease'
Autor:
Alfredo Rodríguez-Cruz, Guadalupe García-Alcocer, Antonio Romo-Mancillas, Jesus Mendiola-Precoma, Laura C. Berumen, Jesica Escobar-Cabrera
Publikováno v:
IBRO Reports, Vol 8, Iss, Pp 28-35 (2020)
IBRO Reports
IBRO Reports
Highlights • Valerenic acid modulates the neuropathological markers of Parkinson´s disease. • Valerenic acid attenuates neuroinflammation in a Parkinson´s disease model. • Astrocytes and cytokines are targets in the anti-inflammatory effect o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b09491839f0fbe941359d445d0490d1
http://www.sciencedirect.com/science/article/pii/S2451830119319405
http://www.sciencedirect.com/science/article/pii/S2451830119319405
Akademický článek
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Akademický článek
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Autor:
Natalia Ninkina, Owen M. Peters, Natalie Connor-Robson, Kirill D. Chaprov, Holger B. Kramer, Dominic J. Withers, Arthur T. Kopylov, Vladimir L. Buchman, Steven Millership, Alex Montoya
Publikováno v:
The Journal of Biological Chemistry
Synucleins, a family of three proteins highly expressed in neurons, are predominantly known for the direct involvement of α-synuclein in the etiology and pathogenesis of Parkinson's and certain other neurodegenerative diseases, but their precise phy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92c25bdcdb04d42ed3e6e25fe31cef99
http://europepmc.org/articles/PMC8633583
http://europepmc.org/articles/PMC8633583
Publikováno v:
Journal of Neuroscience Methods
Background Studying human ageing is of increasing importance due to the worldwide ageing population. However, it faces the challenge of lengthy experiments to produce an ageing phenotype. Often, to recreate the hallmarks of ageing requires complex em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef7cb4171cedd260207f5f3529ff5546
https://hdl.handle.net/10023/23789
https://hdl.handle.net/10023/23789
Publikováno v:
Saudi Journal of Biological Sciences, Vol 26, Iss 8, Pp 1948-1955 (2019)
Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences
Objective: Acupuncture is a commonly used method to provide motor-symptomatic relief for patients with Parkinson s disease (PD). Our objective was to evaluate protective effects of acupuncture treatment and potential underlying mechanisms according t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb11e7f0cebf1afc920e71bba3d8a03f
http://www.sciencedirect.com/science/article/pii/S1319562X19301214
http://www.sciencedirect.com/science/article/pii/S1319562X19301214