Zobrazeno 1 - 10
of 1 730
pro vyhledávání: '"TGR5"'
Autor:
Yanlin Guo, Rongfang Qiao, Guixiang Xie, Yao Yao, Chunxiu Du, Yunxia Shao, Youfei Guan, Xiaoyan Zhang
Publikováno v:
Kidney Diseases, Pp 1-12 (2024)
Introduction: G protein-coupled bile acid receptor (TGR5), the first G protein-coupled receptor for bile acids identified, is capable of activating a variety of intracellular signaling pathways after interacting with bile acids. TGR5 plays an importa
Externí odkaz:
https://doaj.org/article/9742a8d4bd4949298d3932dd080e02cf
Autor:
Friedrich Reusswig, Maria Reich, Leonard Wienands, Diran Herebian, Verena Keitel-Anselmino, Margitta Elvers
Publikováno v:
Platelets, Vol 35, Iss 1 (2024)
AbstractLiver failure and cirrhosis are characterized by abnormal hemostasis with aberrant platelet activation. In particular, the consequences of cholestatic liver disease and molecular mechanisms, including the role of bile acids leading to impaire
Externí odkaz:
https://doaj.org/article/bd0012fe927e40debefd73b999196fd8
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Nonalcoholic fatty liver disease (NAFLD) emerges as the most predominant cause of liver disease, tightly linked to metabolic dysfunction. Bile acids (BAs), initially synthesized from cholesterol in the liver, undergo further metabolism by gut bacteri
Externí odkaz:
https://doaj.org/article/cbf636860fb244698c5b194efae86f22
Autor:
Yixuan Luo, Hui Xue, Xunjiang Wang, Lihong Fu, Wei Li, Xu Wang, Xuan Liu, Wenyuan Lin, Hongli Zhang, Lihua Gu, Zhengtao Wang, Li Yang, Feng Tao, Lili Ding
Publikováno v:
Journal of Functional Foods, Vol 117, Iss , Pp 106213- (2024)
Black ginseng as the functional food, has been used to improve obesity and insulin resistance. However, the underlying mechanism remains unclear. We found that Black ginseng extract (BGS) significantly ameliorated diet-induced obesity and insulin res
Externí odkaz:
https://doaj.org/article/499fe53277b4410daa3b12a09f87d9fe
Autor:
Weijun Lun, Qihao Yan, Xinghua Guo, Minchuan Zhou, Yan Bai, Jincan He, Hua Cao, Qishi Che, Jiao Guo, Zhengquan Su
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 2, Pp 468-491 (2024)
G protein-coupled receptors (GPCRs) are a large family of membrane protein receptors, and Takeda G protein-coupled receptor 5 (TGR5) is a member of this family. As a membrane receptor, TGR5 is widely distributed in different parts of the human body a
Externí odkaz:
https://doaj.org/article/2bca73c040104794b9f24d1ce9a76fae
Publikováno v:
Liver Research, Vol 7, Iss 4, Pp 296-303 (2023)
Over 20% of mortality during acute liver failure is associated with the development of hepatic encephalopathy (HE). Thus, HE is a complication of acute liver failure with a broad spectrum of neuropsychiatric abnormalities ranging from subclinical alt
Externí odkaz:
https://doaj.org/article/27f129de6d274fef91120034bec2282f
Publikováno v:
Cells, Vol 13, Iss 19, p 1650 (2024)
Primary sclerosing cholangitis (PSC) is a rare, chronic liver disease with no approved therapies. The ursodeoxycholic acid (UDCA) has been widely used, although there is no evidence that the use of UDCA delays the time to liver transplant or increase
Externí odkaz:
https://doaj.org/article/8c33c16252b149838b750ac30deaed77
Autor:
Rong Li, Ping Yang, Bowen Liu, Ziru Ye, Puyue Zhang, Mingjian Li, Yanju Gong, Yong Huang, Lan Yang, Min Li
Publikováno v:
Heliyon, Vol 10, Iss 10, Pp e30594- (2024)
Aim: Disturbed intestinal microbiota has been implicated in the inflammatory microenvironment of the colon, which usually results in ulcerative colitis (UC). Given the limitations of these drugs, it is important to explore alternative means of protec
Externí odkaz:
https://doaj.org/article/8b6a7186744f4743b72635485aada79f