Zobrazeno 1 - 10
of 54
pro vyhledávání: '"TGN, trans Golgi network"'
Autor:
Liu Yuqing, Jiang Lixiang, Hung-Fat Tse, Wing-Hon Lai, Rui Wei, Jiayin Yang, Fu Jian, Yang Hu, Wai-Ling Tsang, Yiu-Lam Tse, Bo Yang, Miguel A. Esteban, Xueyu Hong, Ka-Wing Au, Kwong-Man Ng, Chi-Wa Cheng, Wai-In Ho, Na Li
Publikováno v:
JHEP Reports
JHEP Reports, Vol 4, Iss 1, Pp 100389-(2022)
JHEP Reports, Vol 4, Iss 1, Pp 100389-(2022)
Background & Aims Wilson’s disease (WD) is an autosomal recessive disorder of copper metabolism caused by loss-of-function mutations in ATP7B, which encodes a copper-transporting protein. It is characterized by excessive copper deposition in tissue
Autor:
Mitsuhiro Tomosugi, Hiroki Otani, Akari Shintani, Toshihisa Hatta, Junko Hatta, Takashi Mochizuki, Masahide Asano, Hiroki Shoji, Makoto Taniguchi, Keiichi Moriguchi, Hiroki Shimada, Hiromi Sakata-Haga, Tsuyoshi Tsukada, Daisuke Sakai
Publikováno v:
JID Innovations, Vol 1, Iss 3, Pp 100024-(2021)
JID Innovations
JID Innovations
MC5R is known for its role in the exocrine function of sebaceous glands, but other functions in the epidermis remain unclear. This study focused on the relationship between MC5R and homeostasis in the epidermis and examined the role of MC5R in mice w
Autor:
Nadine, Zimmann, Petr, Rada, Vojtěch, Žárský, Tamara, Smutná, Kristína, Záhonová, Joel, Dacks, Karel, Harant, Ivan, Hrdý, Jan, Tachezy
Publikováno v:
Molecular & Cellular Proteomics : MCP
The lysosome represents a central degradative compartment of eukaryote cells, yet little is known about the biogenesis and function of this organelle in parasitic protists. Whereas the mannose 6-phosphate (M6P)-dependent system is dominant for lysoso
Autor:
Bénédicte, Gaborit, Roland, Govers, Alexandre, Altié, Jean Michel, Brunel, Pierre, Morange, Franck, Peiretti
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2021, 297 (1), pp.100818. ⟨10.1016/j.jbc.2021.100818⟩
Journal of Biological Chemistry, 2021, 297 (1), pp.100818. ⟨10.1016/j.jbc.2021.100818⟩
The Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2021, 297 (1), pp.100818. ⟨10.1016/j.jbc.2021.100818⟩
Journal of Biological Chemistry, 2021, 297 (1), pp.100818. ⟨10.1016/j.jbc.2021.100818⟩
The Journal of Biological Chemistry
International audience; The cleavage of the insulin receptor by β-secretase 1 (BACE1) in the liver increases during diabetes, which contributes to reduce insulin receptor levels and impair insulin signaling. However, the precise signaling events tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d438b123de19467c77e8e9b4739301bb
https://hal.archives-ouvertes.fr/hal-03368302
https://hal.archives-ouvertes.fr/hal-03368302
Autor:
Hiroyuki Sugimoto, Yasuhiro Horibata
Publikováno v:
Journal of Lipid Research
Journal of Lipid Research, Vol 62, Iss, Pp 100100-(2021)
Journal of Lipid Research, Vol 62, Iss, Pp 100100-(2021)
Choline phospholipids (PLs) such as phosphatidylcholine (PC) and 1-alkyl-2-acyl-sn-glycerophosphocholine are important components for cell membranes and also serve as a source of several lipid mediators. These lipids are biosynthesized in mammals in
Autor:
Timothy K. Soh, Luca Mascheroni, Vivienne Connor, Katharina M. Scherer, James D. Manton, Clemens F. Kaminski, Colin M. Crump
Publikováno v:
The Journal of Biological Chemistry
Herpesviruses are large and complex viruses that have a long history of coevolution with their host species. One important factor in the virus–host interaction is the alteration of intracellular morphology during viral replication with critical imp
Autor:
Gabriel Talaia, Margarida Casal, Hernâni Gerós, Sandra Paiva, Rosana Maria Abreu Alves, Cláudia Barata-Antunes, Robert Mans
Publikováno v:
Computational and Structural Biotechnology Journal, 19
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 1713-1737 (2021)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 1713-1737 (2021)
Plasma membrane transporters play pivotal roles in the import of nutrients, including sugars, amino acids, nucleobases, carboxylic acids, and metal ions, that surround fungal cells. The selective removal of these transporters by endocytosis is one of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::632ee65f13d8bd8b6a66921459f5d65f
https://hdl.handle.net/1822/72047
https://hdl.handle.net/1822/72047
Publikováno v:
The Journal of Biological Chemistry
Rho/Ras family small GTPases are known to regulate numerous cellular processes, including cytoskeletal reorganization, cell proliferation, and cell differentiation. These processes are also controlled by Ca2+, and consequently, cross talk between the
Autor:
Diego Sbardella, Alessandra di Masi, Giovanna De Simone, Magda Gioia, Giovanni Francesco Fasciglione, Massimo Coletta, Alessio Bocedi, Grazia R. Tundo, Donato Di Pierro, Paolo Ascenzi, Paolo Calligari, Chiara Ciaccio
Publikováno v:
Biochemical Pharmacology
Graphical abstract
In the Fall of 2019 a sudden and dramatic outbreak of a pulmonary disease (Coronavirus Disease COVID-19), due to a new Coronavirus strain (i.e., SARS-CoV-2), emerged in the continental Chinese area of Wuhan and quickly diffuse
In the Fall of 2019 a sudden and dramatic outbreak of a pulmonary disease (Coronavirus Disease COVID-19), due to a new Coronavirus strain (i.e., SARS-CoV-2), emerged in the continental Chinese area of Wuhan and quickly diffuse
Publikováno v:
Biochimica et Biophysica Acta. General Subjects
The Conserved Oligomeric Golgi (COG) complex, a multi-subunit vesicle tethering complex of the CATCHR (Complexes Associated with Tethering Containing Helical Rods) family, controls several aspects of cellular homeostasis by orchestrating retrograde v