Zobrazeno 1 - 10
of 585
pro vyhledávání: '"TGF-β2"'
Autor:
Anh Duy Do, Kuo-Sheng Wu, Shing-Shung Chu, Le Hien Giang, Yu-Ling Lin, Che-Chang Chang, Tai-Tong Wong, Chia-Ling Hsieh, Shian-Ying Sung
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-17 (2024)
Abstract Background Medulloblastomas (MBs) are one of the most common malignant brain tumor types in children. MB prognosis, despite improvement in recent years, still depends on clinical and biological risk factors. Metastasis is the leading cause o
Externí odkaz:
https://doaj.org/article/30d7c3fab6e24875aa0b0f1e9df0d44f
Publikováno v:
Медицинская иммунология, Vol 26, Iss 3, Pp 533-544 (2024)
The issues of recurrencies in chronic rhinosinusitis with nasal polyps (CRSwNP) still remain unresolved. Therefore, detection patients with uncontrolled clinical course of CRSwNP is required.The aim of the present study was to assess cytokine profile
Externí odkaz:
https://doaj.org/article/5245b3e503a44ba687cb25a0d5424893
Publikováno v:
Biomolecules & Biomedicine (2024)
A cataract is a clinically common blinding disease closely related to the ageing of the eye cells, which has become a major health killer in the elderly. Our research seeks to analyze the primary targets linked to the pathogenesis of cataracts during
Externí odkaz:
https://doaj.org/article/bd593616bc3647fab64bc21a4b1386b3
Publikováno v:
Guoji Yanke Zazhi, Vol 23, Iss 7, Pp 1072-1079 (2023)
AIM: To investigate the mechanism of pyrrolidine dithiocarbamate(PDTC)on transforming growth factor-beta 2(TGF-β2)-induced epithelial-mesenchymal transition(EMT)in human lens epithelial cells(LECs).METHODS: LECs were treated with various doses of PD
Externí odkaz:
https://doaj.org/article/cca188880f9441499bae56c726dc3621
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 10, Pp 5048-5066 (2022)
Many elderly individuals frequently experience cataracts that interfere with vision. After cataract surgery, the left lens epithelial cell (LEC) exhibited fibrosis and posterior capsule opacification (PCO). Sometimes, there is a need for a second sur
Externí odkaz:
https://doaj.org/article/ea8dfdb89ea44ba0b1a1b57f50ad76fd
Akademický článek
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Publikováno v:
BMC Ophthalmology, Vol 22, Iss 1, Pp 1-8 (2022)
Abstract Background Transforming growth factor (TGF) is a cytokine that acts on the proliferation, migration, differentiation, and apoptosis of cells and the accumulation of extracellular matrix components. Very few studies have precisely evaluated t
Externí odkaz:
https://doaj.org/article/183cb2de90c1437ca07da772071fdf55
Autor:
Hong Kyu Lee, Min-Woo Nam, Ryeo-Eun Go, Jihye Koo, Tae Hun Kim, Jun-Eui Park, Kyung-Chul Choi
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 159, Iss , Pp 114212- (2023)
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers, with high mortality and recurrence rate. In this study, we generated a human immune system mouse model by transplanting human peripheral blood mononuclear cells into NSG-B
Externí odkaz:
https://doaj.org/article/4bd55cf84e11420f81af692f73eef29b
Autor:
Liqun Tu, Zhe Wang, Lei Yang, Xiaomeng Sun, Yunpeng Yao, Peng Zhang, Xiaotian Zhang, Liying Wang, Yongli Yu, Ming Yang
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionTransforming growth factor β2 (TGF-β2), also known as glioma-derived T-cell suppressor factor, is associated with the impairment of tumor immune surveillance. Therefore, blocking TGF-β2 signaling probably be a feasible strategy to deve
Externí odkaz:
https://doaj.org/article/bda4f96fa16a4d0caae1fb5b1c8d9d9c
Autor:
Tao Su, Suchao Huang, Yanmin Zhang, Yajuan Guo, Shuwei Zhang, Jiaji Guan, Mingjing Meng, Linxin Liu, Caiyan Wang, Dihua Yu, Hiu-Yee Kwan, Zhiying Huang, Qiuju Huang, Elaine Lai-Han Leung, Ming Hu, Ying Wang, Zhongqiu Liu, Linlin Lu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 2, Pp 821-837 (2022)
Acidosis, regardless of hypoxia involvement, is recognized as a chronic and harsh tumor microenvironment (TME) that educates malignant cells to thrive and metastasize. Although overwhelming evidence supports an acidic environment as a driver or ubiqu
Externí odkaz:
https://doaj.org/article/bc87c405eab847c4b530dc144c905dcf