Zobrazeno 1 - 10
of 588
pro vyhledávání: '"TGF-β2"'
Publikováno v:
Open Life Sciences, Vol 19, Iss 1, Pp 7199-212 (2024)
Fibrosis is the primary cause of retinal detachment and visual decline. Here, we investigated the role of Prohibitin 2 (PHB2) in modulating fibrosis in ARPE-19 cells stimulated by transforming growth factor (TGF)-β2. The proliferation, migration, an
Externí odkaz:
https://doaj.org/article/95b0c6b7a5394ce283d7d4d396a797b7
Autor:
Sourav Pal, Sayed Mohammed Firdous
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-25 (2024)
Abstract Cancer is a multifaceted disease characterized by the gradual accumulation of genetic and epigenetic alterations within cells, leading to uncontrolled cell growth and invasive behavior. The intricate interplay between environmental factors,
Externí odkaz:
https://doaj.org/article/accceb8dc1d54cfe8dfbf0af55b29cb3
Publikováno v:
International Journal of General Medicine, Vol Volume 17, Pp 4579-4593 (2024)
Xinyang Nie,1– 3,* Jian Liu,1,2,* Daohan Wang,1,2,* Chuan Li,1,2 Yuxin Teng,1,2 Zhufeng Li,1,2 Yangpu Jia,1,2 Peiyao Wang,1,2 Jingyu Deng,2,3 Weidong Li,1,2 Li Lu1,2 1Department of General Surgery, Tianjin Medical University General Hos
Externí odkaz:
https://doaj.org/article/65a076e3835d476e977db566847c9efb
Estimation of Some Pro- and Anti-Inflammatory Interleukins in Rheumatoid Arthritis of Iraqi Patients
Publikováno v:
Medical Journal of Babylon, Vol 21, Iss 3, Pp 738-741 (2024)
Background:Rheumatoid arthritis (RA) is an inflammatory condition that mostly affects synovial joints. It produces severe swelling and ongoing inflammation, and as it worsens, the cartilage and bone begin to erode, resulting in deformed joints and bo
Externí odkaz:
https://doaj.org/article/c4ed422f47a44c5c9674fea4751cc821
Autor:
Anh Duy Do, Kuo-Sheng Wu, Shing-Shung Chu, Le Hien Giang, Yu-Ling Lin, Che-Chang Chang, Tai-Tong Wong, Chia-Ling Hsieh, Shian-Ying Sung
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-17 (2024)
Abstract Background Medulloblastomas (MBs) are one of the most common malignant brain tumor types in children. MB prognosis, despite improvement in recent years, still depends on clinical and biological risk factors. Metastasis is the leading cause o
Externí odkaz:
https://doaj.org/article/30d7c3fab6e24875aa0b0f1e9df0d44f
Publikováno v:
Медицинская иммунология, Vol 26, Iss 3, Pp 533-544 (2024)
The issues of recurrencies in chronic rhinosinusitis with nasal polyps (CRSwNP) still remain unresolved. Therefore, detection patients with uncontrolled clinical course of CRSwNP is required.The aim of the present study was to assess cytokine profile
Externí odkaz:
https://doaj.org/article/5245b3e503a44ba687cb25a0d5424893
Autor:
Megumi Watanabe, Tatsuya Sato, Toshiyuki Yano, Megumi Higashide, Toshifumi Ogawa, Nami Nishikiori, Masato Furuhashi, Hiroshi Ohguro
Publikováno v:
Biomedicines, Vol 12, Iss 11, p 2604 (2024)
Background/Objectives: Mammalian target of rapamycin (mTOR) inhibition may have been suggested to have a beneficial effect on the glaucomatous human trabecular meshwork (HTM). To study the effects of the mTOR inhibitors rapamycin (Rapa) and Torin1 on
Externí odkaz:
https://doaj.org/article/7d6afdd7daa54d8bb6dc856c439e73b5
Publikováno v:
Biomolecules & Biomedicine (2024)
A cataract is a clinically common blinding disease closely related to the ageing of the eye cells, which has become a major health killer in the elderly. Our research seeks to analyze the primary targets linked to the pathogenesis of cataracts during
Externí odkaz:
https://doaj.org/article/bd593616bc3647fab64bc21a4b1386b3
Autor:
Megumi Higashide, Megumi Watanabe, Tatsuya Sato, Toshifumi Ogawa, Araya Umetsu, Soma Suzuki, Masato Furuhashi, Hiroshi Ohguro, Nami Nishikiori
Publikováno v:
Biomedicines, Vol 12, Iss 10, p 2228 (2024)
Objectives: To study the effects of all-trans retinoic acid (ATRA) on TGF-β2-induced effects of human retinal pigment epithelium cells under normoxia and hypoxia conditions. Methods: Two-dimensionally (2D) and three-dimensionally (3D) cultured ARPE1
Externí odkaz:
https://doaj.org/article/3971cfab9a1f400e91cdbf409217c15b
Publikováno v:
Guoji Yanke Zazhi, Vol 23, Iss 7, Pp 1072-1079 (2023)
AIM: To investigate the mechanism of pyrrolidine dithiocarbamate(PDTC)on transforming growth factor-beta 2(TGF-β2)-induced epithelial-mesenchymal transition(EMT)in human lens epithelial cells(LECs).METHODS: LECs were treated with various doses of PD
Externí odkaz:
https://doaj.org/article/cca188880f9441499bae56c726dc3621