Zobrazeno 1 - 10
of 446
pro vyhledávání: '"TGF-β/Smad signaling"'
Autor:
Rong Zhang, Xiaodan Mu, Dawei Liu, Chider Chen, Bowen Meng, Yan Qu, Jin Liu, Runci Wang, Chuanjie Li, Xueli Mao, Qintao Wang, Qingbin Zhang
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Apoptotic vesicles (apoVs) play a vital role in various physiological and pathological conditions. However, we have yet to fully understand their precise biological effects in rescuing impaired mesenchymal stem cells (MSCs). Here, we proved
Externí odkaz:
https://doaj.org/article/5f18844ad9ab48fba622e6c112c438f7
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 5587-5598 (2024)
Zheng Wang,1,2,* Yifan Wu,1,2,* Wanrong Yi,1,2 Yifeng Yu,1,2 Xue Fang,1,2 Zonghuan Li,1,2 Aixi Yu1,2 1Department of Orthopedic Trauma and Microsurgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, People’s Republic of China; 2Hubei
Externí odkaz:
https://doaj.org/article/e8151731970d492fa131f7bed081f834
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-20 (2024)
Abstract Background Colorectal cancer (CRC) metachronous liver metastasis is a significant clinical challenge, largely attributable to the late detection and the intricate molecular mechanisms that remain poorly understood. This study aims to elucida
Externí odkaz:
https://doaj.org/article/d2c7ba877bff42b7912c05ec03c42379
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e31973- (2024)
Purpose: Endometrial cancer (EC) poses a serious risk to females worldwide; thus, a deep understanding of EC is urgently required. The role and mechanisms of gamma-glutamyltransferase light chain 1 (GGTLC1) in EC remain obscure. This study aims to el
Externí odkaz:
https://doaj.org/article/ca5bacd48f614e96865639b91d35de7c
Autor:
Yong Tang, Yi Liu, Xiaobo Wang, Haiyang Guo, Lin Chen, Guangbing Hu, Yutong Cui, Shiqi Liang, Ji Zuo, Zichen Luo, Xinrui Chen, Xianfei Wang
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-16 (2024)
Abstract Background Colorectal cancer (CRC) is an aggressive tumor of the gastrointestinal tract, which is a major public health concern worldwide. Despite numerous studies, the precise mechanism of metastasis behind its progression remains elusive.
Externí odkaz:
https://doaj.org/article/c3ff4536f47c474884dd3f9af17dbdb3
Publikováno v:
Biomolecules & Biomedicine (2024)
Small Ubiquitin-like Modifier (SUMOylation) regulates a variety of cellular activities, and its dysregulation has been associated with glioma etiology. The aim of this research was to clarify the function of SUMOylation-related genes in glioma and de
Externí odkaz:
https://doaj.org/article/eeef903fc21a400f8a32ea8b0d14d993
Autor:
Nannan Chen, Lianzhi Zhang, Zhang Zhong, Wenjia Zhang, Qunlin Gong, Nan Xu, Yimeng Zhou, Jiahong Wang, Pengxiang Zheng
Publikováno v:
Biomolecules & Biomedicine (2024)
Cardiac arrhythmias are often linked to the overactivity of cardiac fibroblasts (CFs). Investigating the impact of poly (ADP-ribose) polymerase 9 (PARP9) on Angiotensin II (Ang II)-induced fibroblast activation and the therapeutic effects of pirfenid
Externí odkaz:
https://doaj.org/article/6bfe8a72d3304868a8344e7f81a03652
Autor:
Yiyang Zhang, Jun Wang, Meng Zhang, Xiaoyun Li, Fan Zhang, Manlin Zhou, Kun Yang, Weiji Chen, Haie Ding, Xiao Tan, Qian Zhang, Zilin Qiao
Publikováno v:
Animals, Vol 14, Iss 16, p 2422 (2024)
The aim of this study was to investigate the effects of hypoxia-induced phenotype, glucose metabolism, ROS levels, and the PDK1-mediated regulation of TGF-β/Smad signaling in yellow cattles, yaks, and those overexpressing PDK1 PASMCs using growth cu
Externí odkaz:
https://doaj.org/article/7f1950bf22c14444b81e599b6ba772a3
Publikováno v:
陆军军医大学学报, Vol 45, Iss 11, Pp 1181-1188 (2023)
Objective To investigate the regulative role of FKBP10 in the progression of gastric cancer and the underlying mechanism. Methods Bioinformatics analysis was applied to detect the expression of FKBP10 in gastric cancer samples and normal samples, as
Externí odkaz:
https://doaj.org/article/bd09932aba074046b14a2bf8680d3dcb
Autor:
Juan Li, Lirong Gao, Anqi Wang, Huiwen Qian, Jianjie Zhu, Shundong Ji, Jun Chen, Zeyi Liu, Cheng Ji
Publikováno v:
Cancer Medicine, Vol 12, Iss 8, Pp 9826-9842 (2023)
Abstract Background Forkhead box L2 (FOXL2) has been recognized as a transcription factor in the progression of many malignancies, but its role in non‐small cell lung cancer (NSCLC) remains unclear. This research clarified on the role of FOXL2 and
Externí odkaz:
https://doaj.org/article/edd51f82f98e4739b5e03ebc051ed134