Zobrazeno 1 - 10
of 232
pro vyhledávání: '"TGF-β/Smad pathway"'
Autor:
Liu Siyuan, Cao Fan, Ding Jingjing, Wang Chuanxi, Ding Biqing, Liang Kun, Jiang Zhengxuan, Bao Ning
Publikováno v:
Guoji Yanke Zazhi, Vol 24, Iss 1, Pp 18-23 (2024)
AIM: To explore the dynamic expression of high mobility group box 1(HMGB1)in scar tissues after glaucoma drainage valve implantation, and to further reveal the role and possible mechanism of HMGB1 in scarring after glaucoma surgery.METHODS: A total o
Externí odkaz:
https://doaj.org/article/c1c1b11900934fa7a57c3ec48aa8d2e8
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Membrane materials were widely used in guided tissue regeneration (GTR) to prevent fibroblast invasion and form a confined area for preferentially growing of osteoblast. A novel collagen-hyaluronate composite gradient membrane was prepared by Tilapia
Externí odkaz:
https://doaj.org/article/3ed55c86361a487b8ff958b098f9d0d9
Publikováno v:
Cancer Biology & Therapy, Vol 23, Iss 1, Pp 225-233 (2022)
Glioma is a primary intracranial malignant tumor with poor prognosis, and its pathogenesis is unclear. This study discussed the impact of p53/lncRNA plasmacytoma variant translocation 1 (lncRNA PVT1)/transforming growth factor beta (TGF-β)/Smad axis
Externí odkaz:
https://doaj.org/article/ed86be1972054b8da26beaa8c9ad54af
Publikováno v:
Molecules, Vol 29, Iss 2, p 401 (2024)
The leaves of C. tiglium have been comprehensively researched for their structurally novel bioactive natural compounds, especially those with anti-schistosomiasis liver fibrosis activity, because ethyl acetate extract, which can be extracted from the
Externí odkaz:
https://doaj.org/article/462fe0fe5de2474e89fb74e4ac92b92a
Autor:
Xudong Song, Jiayi Shi, Jieting Liu, Yong Liu, Yang Yu, Yufei Qiu, Zhiqin Cao, Yu Pan, Xiaohuan Yuan, Yanhui Chu, Dan Wu
Publikováno v:
Molecular Medicine, Vol 28, Iss 1, Pp 1-15 (2022)
Abstract Background Liver fibrosis is a progressive liver injury response. Transforming growth factor β1 (TGF-β1) is oversecreted during liver fibrosis and promotes the development of liver fibrosis. Therapeutic approaches targeting TGF-β1 and its
Externí odkaz:
https://doaj.org/article/9258887cfd62423ab08d31129e13a465
Publikováno v:
Hypertension in Pregnancy, Vol 41, Iss 2, Pp 116-125 (2022)
Animal experiments showed that PIH rats had increased mean arterial pressure (MAP), systolic blood pressure (SBP), and diastolic blood pressure (DBP), but decreased litter size, number of viable fetuses, fetal weight, and placental weight. The higher
Externí odkaz:
https://doaj.org/article/a7720e6db3aa4186bcf8110a513fbd56
Akademický článek
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Autor:
Yunqi Yao, Zhemin Xia, Fuyi Cheng, Qingyuan Jang, Jiao He, Cheng Pan, Lin Zhang, Yixin Ye, Yuan Wang, Shuang Chen, Dongsheng Su, Xiaolan Su, Lin Cheng, Gang Shi, Lei Dai, Hongxin Deng
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-14 (2021)
Abstract Background Liver fibrosis (LF) is a common pathological process characterized by the activation of hepatic stellate cells (HSCs) and accumulation of extracellular matrix. Severe LF causes cirrhosis and even liver failure, a major cause of mo
Externí odkaz:
https://doaj.org/article/54d6383d195d4bcca7bca909edab9a4a
Autor:
Bolin Cai, Zhenhui Li, Manting Ma, Jing Zhang, Shaofen Kong, Bahareldin Ali Abdalla, Haiping Xu, Endashaw Jebessa, Xiquan Zhang, Raman Akinyanju Lawal, Qinghua Nie
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 23, Iss , Pp 512-526 (2021)
As the world population grows, muscle atrophy leading to muscle wasting could become a bigger risk. Long noncoding RNAs (lncRNAs) are known to play important roles in muscle growth and muscle atrophy. Meanwhile, it has recently come to light that man
Externí odkaz:
https://doaj.org/article/58e6b12bcf9748b5b167851a30d2c167
Publikováno v:
BMC Nephrology, Vol 21, Iss 1, Pp 1-9 (2020)
Abstract Background Hydrogen sulfide (H2S) has been shown to inhibit the atherosclerosis development and progression. It is produced by cystathionine γ-lyase (CSE) in the cardiovascular system. In our previous study, it has been shown that CSE/H2S s
Externí odkaz:
https://doaj.org/article/8721baa4a68745f28347f8dc9648afde