Zobrazeno 1 - 10
of 66
pro vyhledávání: '"TGFβ, Transforming growth factor beta"'
Autor:
Helen Carrasco Hope, Gabriella Pickersgill, Pierpaolo Ginefra, Nicola Vannini, Graham P. Cook, Robert J. Salmond
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
T cell activation is dependent upon the integration of antigenic, co-stimulatory and cytokine-derived signals and the availability and acquisition of nutrients from the environment. Furthermore, T cell activation is accompanied by reprogramming of ce
Externí odkaz:
https://doaj.org/article/d81420ad01cb441db801bd0ef0b2bfef
Autor:
David A. Frank, Isidora Tošić
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 12, Pp 1167-1178 (2021)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 12, Pp 1167-1178 (2021)
The oncogenic transcription factor signal transducer and activator of transcription 3 (STAT3) is activated constitutively in a wide array of human cancers. It is an appealing molecular target for novel therapy as it directly regulates expression of g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95fc1e221705a2edcb47149735290583
http://europepmc.org/articles/PMC8569436
http://europepmc.org/articles/PMC8569436
Autor:
Ahmed S. Sultan, Mahmoud I. Khalil, Nada S. Badr, Afrah F. Alkhuriji, Mohamed S.A. El-Gerbed, Nabila E. Abdelmeguid
Publikováno v:
Saudi Journal of Biological Sciences, Vol 28, Iss 4, Pp 2254-2266 (2021)
Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences
Colostrum, the sole diet for newborns, is an emerging nutraceutical. To date, the chemopreventive effect of Bovine Colostrum against liver injury induced by the potent carcinogen, 7,12-dimethyl-Benz[a]anthracene (DMBA) is unexplored. Humans are daily
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8590044845bd4b17693f357c2745c87
https://doi.org/10.1016/j.sjbs.2021.01.016
https://doi.org/10.1016/j.sjbs.2021.01.016
Autor:
Sara M. Dann, Zheng Zhou, Suxia Yao, Wenjing Yang, Anthony J. Bilotta, Yu Yu, Xiaojing Zhao, Chunyan Ma, Yingzi Cong, Yanbo Yu
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 1023-1044 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background and Aims Gut bacteria-derived short-chain fatty acids (SCFAs) play crucial roles in the maintenance of intestinal homeostasis. However, how SCFAs regulate epithelial turnover and tissue repair remain incompletely understood. In this study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8d4114ca3e9339e1b8954fbfbdd4b9d
http://www.sciencedirect.com/science/article/pii/S2352345X20301909
http://www.sciencedirect.com/science/article/pii/S2352345X20301909
Autor:
Robert W. Harrison, Sitharthan Sekar, Svati H. Shah, Sreekanth Vemulapalli, Eric Black-Maier, Rahul S. Loungani, Michael Rehorn
Publikováno v:
JACC: Case Reports, Vol 2, Iss 11, Pp 1662-1666 (2020)
JACC Case Reports
JACC Case Reports
A 69-year-old man with a history of coronary artery ectasia, potentially resulting from an underlying heritable connective tissue disorder, presented with ventricular fibrillation. Despite medical management of ischemia, he developed recurrent ventri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::427a6925914734059199154eb0f721c2
http://www.sciencedirect.com/science/article/pii/S2666084920308421
http://www.sciencedirect.com/science/article/pii/S2666084920308421
Autor:
Alexandra Naba, Gavin E. Arteel
Publikováno v:
JHEP Reports
Summary The extracellular matrix (ECM) is a diverse microenvironment that maintains bidirectional communication with surrounding cells to regulate cell and tissue homeostasis. The classical definition of the ECM has more recently been extended to inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5aa8588f766d9c0c42e936d3978c29f
Publikováno v:
Frontiers in immunology, vol. 13, pp. 913184
T cell activation is dependent upon the integration of antigenic, co-stimulatory and cytokine-derived signals and the availability and acquisition of nutrients from the environment. Furthermore, T cell activation is accompanied by reprogramming of ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bed3772124a3826634bf241597ebea5e
https://serval.unil.ch/notice/serval:BIB_1D68C4F5AEAF
https://serval.unil.ch/notice/serval:BIB_1D68C4F5AEAF
Publikováno v:
Molecular Immunology
Highlights • Neutrophils play important roles throughout the metastatic process. • Tumour progression and invasion are influenced by infiltrating neutrophils. • Signalling from neutrophils can enhance survival of circulating tumour cells. • N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d05ffecb2e3e5baeafd2f36b05b85ae
https://doi.org/10.1016/j.molimm.2017.12.013
https://doi.org/10.1016/j.molimm.2017.12.013
Autor:
Victoria Karakis, Adriana San Miguel, Jessica Mahinthakumar, Celeste Carberry, Balaji M. Rao, Adam Mischler, Julia E. Rager, Rebecca C. Fry
Publikováno v:
The Journal of Biological Chemistry
The trophectoderm layer of the blastocyst-stage embryo is the precursor for all trophoblast cells in the placenta. Human trophoblast stem (TS) cells have emerged as an attractive tool for studies on early trophoblast development. However, the use of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e218649239c12b2ad7937121815a16bc
http://europepmc.org/articles/PMC7948510
http://europepmc.org/articles/PMC7948510
Autor:
Anja Jaeschke, David Y. Hui, Anton J.M. Roebroek, April Haller, Christopher Nam, Emily Igel, James G. Cash
Publikováno v:
Journal of Lipid Research, Vol 62, Iss, Pp 100012-(2021)
Journal of Lipid Research
Journal of Lipid Research
The LDL receptor-related protein-1 (LRP1) is highly expressed in numerous cell types, and its impairment is associated with obesity, diabetes, and fatty liver disease. However, the mechanisms linking LRP1 to metabolic disease are not completely under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c290f4d72cef781f80ddd5245699b83
https://lirias.kuleuven.be/handle/20.500.12942/704812
https://lirias.kuleuven.be/handle/20.500.12942/704812