Injected matrix stimulates myogenesis and regeneration of mouse skeletal muscle after ischaemic injury

Autor: D Kuraitis, D Ebadi, P Zhang, E Rizzuto, B Vulesevic, DT Padavan, A Al Madhoun, KA McEwan, T Sofrenovic, K Nicholson, SC Whitman, TG Mesana, IS Skerjanc, A Musarò, M Ruel, EJ Suuronen

Publikováno v: European Cells & Materials, Vol 24, Pp 175-196 (2012)

Biomaterial-guided regeneration represents a novel approach for the treatment of myopathies. Revascularisation and the intramuscular extracellular matrix are important factors in stimulating myogenesis and regenerating muscle damaged by ischaemia. In

Externí odkaz: https://doaj.org/article/fe76988df49a4945b0251c9959cf04dd

Prediction of acute kidney injury risk after cardiac surgery: using a hybrid machine learning algorithm.

Autor: Petrosyan Y; Cardiocore Big Data Research Unit, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, K1Y 4W7, Canada., Mesana TG; Cardiocore Big Data Research Unit, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, K1Y 4W7, Canada., Sun LY; Cardiocore Big Data Research Unit, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, K1Y 4W7, Canada. lsun@ottawaheart.ca.; Division of Cardiac Anesthesiology, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, K1Y 4W7, Canada. lsun@ottawaheart.ca.; School of Epidemiology and Public Health, University of Ottawa, 600 Peter Morand Cres, Ottawa, ON, K1G 5Z3, Canada. lsun@ottawaheart.ca.

Publikováno v: BMC medical informatics and decision making [BMC Med Inform Decis Mak] 2022 May 18; Vol. 22 (1), pp. 137. Date of Electronic Publication: 2022 May 18.

Derivation and validation of a clinical risk score to predict death among patients awaiting cardiac surgery in Ontario, Canada: a population-based study.

Autor: Sun LY; Division of Cardiac Anesthesiology (Sun), University of Ottawa Heart Institute; School of Epidemiology and Public Health (Sun), University of Ottawa, Ottawa, Ont.; ICES (Sun, Wijeysundera, Lee, Eddeen); Schulich Heart Program (Wijeysundera), Sunnybrook Health Sciences Centre; Division of Cardiology (Wijeysundera), Department of Medicine, University of Toronto; Institute of Health Policy, Management and Evaluation (Wijeysundera), University of Toronto; Peter Munk Cardiac Centre (Lee), University Health Network, University of Toronto, Toronto, Ont.; Department of Critical Care Medicine (van Diepen), University of Alberta; Division of Cardiology (van Diepen), Department of Medicine, University of Alberta, Edmonton, Alta.; Division of Cardiac Surgery (Ruel, Mesana), University of Ottawa Heart Institute, Ottawa, Ont. lsun@ottawaheart.ca., Wijeysundera HC; Division of Cardiac Anesthesiology (Sun), University of Ottawa Heart Institute; School of Epidemiology and Public Health (Sun), University of Ottawa, Ottawa, Ont.; ICES (Sun, Wijeysundera, Lee, Eddeen); Schulich Heart Program (Wijeysundera), Sunnybrook Health Sciences Centre; Division of Cardiology (Wijeysundera), Department of Medicine, University of Toronto; Institute of Health Policy, Management and Evaluation (Wijeysundera), University of Toronto; Peter Munk Cardiac Centre (Lee), University Health Network, University of Toronto, Toronto, Ont.; Department of Critical Care Medicine (van Diepen), University of Alberta; Division of Cardiology (van Diepen), Department of Medicine, University of Alberta, Edmonton, Alta.; Division of Cardiac Surgery (Ruel, Mesana), University of Ottawa Heart Institute, Ottawa, Ont., Lee DS; Division of Cardiac Anesthesiology (Sun), University of Ottawa Heart Institute; School of Epidemiology and Public Health (Sun), University of Ottawa, Ottawa, Ont.; ICES (Sun, Wijeysundera, Lee, Eddeen); Schulich Heart Program (Wijeysundera), Sunnybrook Health Sciences Centre; Division of Cardiology (Wijeysundera), Department of Medicine, University of Toronto; Institute of Health Policy, Management and Evaluation (Wijeysundera), University of Toronto; Peter Munk Cardiac Centre (Lee), University Health Network, University of Toronto, Toronto, Ont.; Department of Critical Care Medicine (van Diepen), University of Alberta; Division of Cardiology (van Diepen), Department of Medicine, University of Alberta, Edmonton, Alta.; Division of Cardiac Surgery (Ruel, Mesana), University of Ottawa Heart Institute, Ottawa, Ont., van Diepen S; Division of Cardiac Anesthesiology (Sun), University of Ottawa Heart Institute; School of Epidemiology and Public Health (Sun), University of Ottawa, Ottawa, Ont.; ICES (Sun, Wijeysundera, Lee, Eddeen); Schulich Heart Program (Wijeysundera), Sunnybrook Health Sciences Centre; Division of Cardiology (Wijeysundera), Department of Medicine, University of Toronto; Institute of Health Policy, Management and Evaluation (Wijeysundera), University of Toronto; Peter Munk Cardiac Centre (Lee), University Health Network, University of Toronto, Toronto, Ont.; Department of Critical Care Medicine (van Diepen), University of Alberta; Division of Cardiology (van Diepen), Department of Medicine, University of Alberta, Edmonton, Alta.; Division of Cardiac Surgery (Ruel, Mesana), University of Ottawa Heart Institute, Ottawa, Ont., Ruel M; Division of Cardiac Anesthesiology (Sun), University of Ottawa Heart Institute; School of Epidemiology and Public Health (Sun), University of Ottawa, Ottawa, Ont.; ICES (Sun, Wijeysundera, Lee, Eddeen); Schulich Heart Program (Wijeysundera), Sunnybrook Health Sciences Centre; Division of Cardiology (Wijeysundera), Department of Medicine, University of Toronto; Institute of Health Policy, Management and Evaluation (Wijeysundera), University of Toronto; Peter Munk Cardiac Centre (Lee), University Health Network, University of Toronto, Toronto, Ont.; Department of Critical Care Medicine (van Diepen), University of Alberta; Division of Cardiology (van Diepen), Department of Medicine, University of Alberta, Edmonton, Alta.; Division of Cardiac Surgery (Ruel, Mesana), University of Ottawa Heart Institute, Ottawa, Ont., Eddeen AB; Division of Cardiac Anesthesiology (Sun), University of Ottawa Heart Institute; School of Epidemiology and Public Health (Sun), University of Ottawa, Ottawa, Ont.; ICES (Sun, Wijeysundera, Lee, Eddeen); Schulich Heart Program (Wijeysundera), Sunnybrook Health Sciences Centre; Division of Cardiology (Wijeysundera), Department of Medicine, University of Toronto; Institute of Health Policy, Management and Evaluation (Wijeysundera), University of Toronto; Peter Munk Cardiac Centre (Lee), University Health Network, University of Toronto, Toronto, Ont.; Department of Critical Care Medicine (van Diepen), University of Alberta; Division of Cardiology (van Diepen), Department of Medicine, University of Alberta, Edmonton, Alta.; Division of Cardiac Surgery (Ruel, Mesana), University of Ottawa Heart Institute, Ottawa, Ont., Mesana TG; Division of Cardiac Anesthesiology (Sun), University of Ottawa Heart Institute; School of Epidemiology and Public Health (Sun), University of Ottawa, Ottawa, Ont.; ICES (Sun, Wijeysundera, Lee, Eddeen); Schulich Heart Program (Wijeysundera), Sunnybrook Health Sciences Centre; Division of Cardiology (Wijeysundera), Department of Medicine, University of Toronto; Institute of Health Policy, Management and Evaluation (Wijeysundera), University of Toronto; Peter Munk Cardiac Centre (Lee), University Health Network, University of Toronto, Toronto, Ont.; Department of Critical Care Medicine (van Diepen), University of Alberta; Division of Cardiology (van Diepen), Department of Medicine, University of Alberta, Edmonton, Alta.; Division of Cardiac Surgery (Ruel, Mesana), University of Ottawa Heart Institute, Ottawa, Ont.

Publikováno v: CMAJ open [CMAJ Open] 2022 Mar 08; Vol. 10 (1), pp. E173-E182. Date of Electronic Publication: 2022 Mar 08 (Print Publication: 2022).

Derivation and validation of a clinical model to predict death or cardiac hospitalizations while on the cardiac surgery waitlist.

Autor: Sun LY; Division of Cardiac Anesthesiology (Sun), University of Ottawa Heart Institute and the School of Epidemiology and Public Health, University of Ottawa; ICES uOttawa (Sun, Bader Eddeen), Ottawa, Ont.; ICES Central (Wijeysundera, Tam); Schulich Heart Program (Wijeysundera), Sunnybrook Health Sciences Centre; Division of Cardiology (Wijeysundera), Department of Medicine and Institute for Health Policy, Management and Evaluation, University of Toronto, Toronto, Ont.; Keele Cardiovascular Research Group (Mamas), Centre for Prognosis Research, Institutes of Applied Clinical Science and Primary Care and Health Sciences, Keele University, Staffordshire, UK; Department of Cardiology (Mamas), Royal Stoke University Hospital, Stoke-on-Trent, UK; Division of Cardiac Surgery (Tam), Sunnybrook Health Sciences Centre, Toronto, Ont.; Division of Cardiac Surgery (Mesana), University of Ottawa Heart Institute, Ottawa, Ont. lsun@ottawaheart.ca., Eddeen AB; Division of Cardiac Anesthesiology (Sun), University of Ottawa Heart Institute and the School of Epidemiology and Public Health, University of Ottawa; ICES uOttawa (Sun, Bader Eddeen), Ottawa, Ont.; ICES Central (Wijeysundera, Tam); Schulich Heart Program (Wijeysundera), Sunnybrook Health Sciences Centre; Division of Cardiology (Wijeysundera), Department of Medicine and Institute for Health Policy, Management and Evaluation, University of Toronto, Toronto, Ont.; Keele Cardiovascular Research Group (Mamas), Centre for Prognosis Research, Institutes of Applied Clinical Science and Primary Care and Health Sciences, Keele University, Staffordshire, UK; Department of Cardiology (Mamas), Royal Stoke University Hospital, Stoke-on-Trent, UK; Division of Cardiac Surgery (Tam), Sunnybrook Health Sciences Centre, Toronto, Ont.; Division of Cardiac Surgery (Mesana), University of Ottawa Heart Institute, Ottawa, Ont., Wijeysundera HC; Division of Cardiac Anesthesiology (Sun), University of Ottawa Heart Institute and the School of Epidemiology and Public Health, University of Ottawa; ICES uOttawa (Sun, Bader Eddeen), Ottawa, Ont.; ICES Central (Wijeysundera, Tam); Schulich Heart Program (Wijeysundera), Sunnybrook Health Sciences Centre; Division of Cardiology (Wijeysundera), Department of Medicine and Institute for Health Policy, Management and Evaluation, University of Toronto, Toronto, Ont.; Keele Cardiovascular Research Group (Mamas), Centre for Prognosis Research, Institutes of Applied Clinical Science and Primary Care and Health Sciences, Keele University, Staffordshire, UK; Department of Cardiology (Mamas), Royal Stoke University Hospital, Stoke-on-Trent, UK; Division of Cardiac Surgery (Tam), Sunnybrook Health Sciences Centre, Toronto, Ont.; Division of Cardiac Surgery (Mesana), University of Ottawa Heart Institute, Ottawa, Ont., Mamas MA; Division of Cardiac Anesthesiology (Sun), University of Ottawa Heart Institute and the School of Epidemiology and Public Health, University of Ottawa; ICES uOttawa (Sun, Bader Eddeen), Ottawa, Ont.; ICES Central (Wijeysundera, Tam); Schulich Heart Program (Wijeysundera), Sunnybrook Health Sciences Centre; Division of Cardiology (Wijeysundera), Department of Medicine and Institute for Health Policy, Management and Evaluation, University of Toronto, Toronto, Ont.; Keele Cardiovascular Research Group (Mamas), Centre for Prognosis Research, Institutes of Applied Clinical Science and Primary Care and Health Sciences, Keele University, Staffordshire, UK; Department of Cardiology (Mamas), Royal Stoke University Hospital, Stoke-on-Trent, UK; Division of Cardiac Surgery (Tam), Sunnybrook Health Sciences Centre, Toronto, Ont.; Division of Cardiac Surgery (Mesana), University of Ottawa Heart Institute, Ottawa, Ont., Tam DY; Division of Cardiac Anesthesiology (Sun), University of Ottawa Heart Institute and the School of Epidemiology and Public Health, University of Ottawa; ICES uOttawa (Sun, Bader Eddeen), Ottawa, Ont.; ICES Central (Wijeysundera, Tam); Schulich Heart Program (Wijeysundera), Sunnybrook Health Sciences Centre; Division of Cardiology (Wijeysundera), Department of Medicine and Institute for Health Policy, Management and Evaluation, University of Toronto, Toronto, Ont.; Keele Cardiovascular Research Group (Mamas), Centre for Prognosis Research, Institutes of Applied Clinical Science and Primary Care and Health Sciences, Keele University, Staffordshire, UK; Department of Cardiology (Mamas), Royal Stoke University Hospital, Stoke-on-Trent, UK; Division of Cardiac Surgery (Tam), Sunnybrook Health Sciences Centre, Toronto, Ont.; Division of Cardiac Surgery (Mesana), University of Ottawa Heart Institute, Ottawa, Ont., Mesana TG; Division of Cardiac Anesthesiology (Sun), University of Ottawa Heart Institute and the School of Epidemiology and Public Health, University of Ottawa; ICES uOttawa (Sun, Bader Eddeen), Ottawa, Ont.; ICES Central (Wijeysundera, Tam); Schulich Heart Program (Wijeysundera), Sunnybrook Health Sciences Centre; Division of Cardiology (Wijeysundera), Department of Medicine and Institute for Health Policy, Management and Evaluation, University of Toronto, Toronto, Ont.; Keele Cardiovascular Research Group (Mamas), Centre for Prognosis Research, Institutes of Applied Clinical Science and Primary Care and Health Sciences, Keele University, Staffordshire, UK; Department of Cardiology (Mamas), Royal Stoke University Hospital, Stoke-on-Trent, UK; Division of Cardiac Surgery (Tam), Sunnybrook Health Sciences Centre, Toronto, Ont.; Division of Cardiac Surgery (Mesana), University of Ottawa Heart Institute, Ottawa, Ont.

Publikováno v: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne [CMAJ] 2021 Aug 30; Vol. 193 (34), pp. E1333-E1340.

Disability-free survival after major cardiac surgery: a population-based retrospective cohort study.

Autor: Sun LY; The Division of Cardiac Anesthesiology, Department of Anesthesiology and Pain Medicine (Sun), University of Ottawa Heart Institute; the School of Epidemiology and Public Health (Sun), University of Ottawa; the Institute for Clinical Evaluative Sciences (Sun, Bader Eddeen); the Division of Cardiac Surgery, Department of Surgery (Mesana), University of Ottawa Heart Institute, Ottawa, Ont. lsun@ottawaheart.ca., Eddeen AB; The Division of Cardiac Anesthesiology, Department of Anesthesiology and Pain Medicine (Sun), University of Ottawa Heart Institute; the School of Epidemiology and Public Health (Sun), University of Ottawa; the Institute for Clinical Evaluative Sciences (Sun, Bader Eddeen); the Division of Cardiac Surgery, Department of Surgery (Mesana), University of Ottawa Heart Institute, Ottawa, Ont., Mesana TG; The Division of Cardiac Anesthesiology, Department of Anesthesiology and Pain Medicine (Sun), University of Ottawa Heart Institute; the School of Epidemiology and Public Health (Sun), University of Ottawa; the Institute for Clinical Evaluative Sciences (Sun, Bader Eddeen); the Division of Cardiac Surgery, Department of Surgery (Mesana), University of Ottawa Heart Institute, Ottawa, Ont.

Publikováno v: CMAJ open [CMAJ Open] 2021 Apr 16; Vol. 9 (2), pp. E384-E393. Date of Electronic Publication: 2021 Apr 16 (Print Publication: 2021).