Zobrazeno 1 - 10
of 16
pro vyhledávání: '"TFr1, transferrin receptor 1"'
Publikováno v:
Seminars in Hematology
Iron is a micronutrient essential for a wide range of metabolic processes in virtually all living organisms. During infections, a battle for iron takes place between the human host and the invading pathogens. The liver peptide hepcidin, which is phyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dc3fa6e04512f7c69566588256aa326
http://europepmc.org/articles/PMC8305218
http://europepmc.org/articles/PMC8305218
Autor:
Jaekwon Lee, Yongeun Kim, Jin Seon Yook, Mi Zhou, Zhenhua Liu, Young Cheul Kim, Mikyoung You, Soonkyu Chung
Publikováno v:
The Journal of Biological Chemistry
The development of thermogenic adipocytes concurs with mitochondrial biogenesis, an iron-dependent pathway. Iron regulatory proteins (IRP) 1 and 2 are RNA-binding proteins that regulate intracellular iron homeostasis. IRPs bind to the iron-response e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a7b937089c8ea5dad2ce0b62832588
https://pubmed.ncbi.nlm.nih.gov/33631196
https://pubmed.ncbi.nlm.nih.gov/33631196
Autor:
Nuria García-Magro, Cristina Fernández-Mendívil, Enrique Luengo, Paula Trigo-Alonso, Pilar Negredo, Manuela G. López
Publikováno v:
Redox Biology, Vol 38, Iss, Pp 101789-(2021)
Redox Biology
Redox Biology
Heme oxygenase-1 (HO-1) is an inducible enzyme known for its anti-inflammatory, antioxidant and neuroprotective effects. However, increased expression of HO-1 during aging and age-related neurodegenerative diseases have been associated to neurotoxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43dfb34480f285e42eea2931b0cfeb92
http://www.sciencedirect.com/science/article/pii/S2213231720309940
http://www.sciencedirect.com/science/article/pii/S2213231720309940
Publikováno v:
The Journal of Biological Chemistry
Birt-Hogg-Dubé (BHD) syndrome is a multiorgan disorder caused by inactivation of the folliculin (FLCN) protein. Previously, we identified FLCN as a binding protein of Rab11A, a key regulator of the endocytic recycling pathway. This finding implies t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34690bccc7c80fc336ddab9214444578
https://doi.org/10.1016/j.jbc.2021.100426
https://doi.org/10.1016/j.jbc.2021.100426
Publikováno v:
Pharmacological Research
Graphical abstract
The anti-malarial drugs chloroquine (CQ) and primarily the less toxic hydroxychloroquine (HCQ) are currently used to treat autoimmune diseases for their immunomodulatory and anti-thrombotic properties. They have also been prop
The anti-malarial drugs chloroquine (CQ) and primarily the less toxic hydroxychloroquine (HCQ) are currently used to treat autoimmune diseases for their immunomodulatory and anti-thrombotic properties. They have also been prop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f81981d48efa7707f803b4fdebc173bc
https://doi.org/10.1016/j.phrs.2020.104904
https://doi.org/10.1016/j.phrs.2020.104904
Publikováno v:
Redox Biology, Vol 2, Iss C, Pp 563-569 (2014)
Redox Biology
Redox Biology
Curcumin has been shown to have many potentially health beneficial properties in vitro and in animal models with clinical studies on the toxicity of curcumin reporting no major side effects. However, curcumin may chelate dietary trace elements and co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34111eb52cef8c02b7b58ec3fd7d6591
http://www.sciencedirect.com/science/article/pii/S2213231714000330
http://www.sciencedirect.com/science/article/pii/S2213231714000330
Publikováno v:
Journal of Structural Biology
As obligate parasites, viruses are required to enter and replicate within their host, a process which employs many of their proteins to hijack natural cellular processes. High resolution X-ray crystallographic analysis has proven to be an ideal metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d4416ae646aeb36df1973849ecf272d
https://ora.ox.ac.uk/objects/uuid:ee8668c0-7627-4895-abe4-9dd97779314f
https://ora.ox.ac.uk/objects/uuid:ee8668c0-7627-4895-abe4-9dd97779314f
Publikováno v:
Biochemical Journal
The IKK [inhibitor of NF-κB (nuclear factor κB) kinase] complex has an essential role in the activation of the family of NF-κB transcription factors in response to a variety of stimuli. To identify novel IKK-interacting proteins, we performed an u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a7d6ba59555e88eb22cd73d6b2be0fc
https://pubmed.ncbi.nlm.nih.gov/23016877
https://pubmed.ncbi.nlm.nih.gov/23016877
Akademický článek
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Autor:
Akira Iwase, Chiharu Ishida, Yue Wang, Fumiya Ito, Lei Shi, Hideko Nagasawa, Yuka Hattori, Shinya Toyokuni, Masato Niwa, Masahiko Mori, Fumitaka Kikkawa, Tasuku Hirayama
Publikováno v:
Redox Biology
Ovarian endometriosis is a recognized risk for infertility and epithelial ovarian cancer, presumably due to iron overload resulting from repeated hemorrhage. To find a clue for early detection and prevention of ovarian endometriosis-associated cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c4f1fc3abfef28ebe8d90673a382201