Zobrazeno 1 - 10
of 514
pro vyhledávání: '"TFRC"'
Autor:
Bo Peng, Zhiwei Feng, Ao Yang, Jinmin Liu, Jinwen He, Lihu Xu, Cong Tian, Xiaoyun Sheng, Yaobin Wang, Rongjin Chen, Xingwen Wang, Xiaojun Ren, Bin Geng, Yayi Xia
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-17 (2024)
Abstract Background In clinical practice, alterations in the internal environment of type 2 diabetes can significantly affect bone quality. While the increased risk of fractures among diabetic patients is well-established, the precise mechanisms by w
Externí odkaz:
https://doaj.org/article/682f870a2e6c47609b737437634ca8d6
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-11 (2024)
Abstract Background Sepsis-induced pulmonary injury (SPI) is a common complication of sepsis with a high rate of mortality. N4-acetylcytidine (ac4C) is mediated by the ac4C “writer”, N-acetyltransferase (NAT)10, to regulate the stabilization of m
Externí odkaz:
https://doaj.org/article/e9ef8244ad9e415a9778ea7e8e655c1f
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-16 (2024)
Abstract Background Pulmonary arterial hypertension (PAH) is a life-threatening chronic cardiopulmonary disease. However, there is a paucity of studies that reflect the available biomarkers from separate gene expression profiles in PAH. Methods The G
Externí odkaz:
https://doaj.org/article/6f21ee13d0ea438c9ec35db19e306863
Autor:
Jichao Zhou, Yuanyuan Liu, Xiaoli Wei, Meng Yuan, Xu Zhang, Lingfeng Qin, Bing Cui, Pingping Li, Jing Zhang, Ziming Feng, Jianshuang Jiang, Xiang Yuan, Ruibing Xu, Zhimeng Zhang, Peicheng Zhang, Xiaowei Zhang, Yanan Yang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 7, Pp 3125-3139 (2024)
Zhigancao decoction is a traditional prescription for treating irregular pulse and palpitations in China. As the monarch drug of Zhigancao decoction, the bioactive molecules of licorice against heart diseases remain elusive. We established the HRESIM
Externí odkaz:
https://doaj.org/article/d64ea3d4f5c1435586027e45ce3b8233
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Ovarian cancer (OC) is a malignancy among female globally. Circular RNAs (circRNAs) are a family of circular endogenous RNAs generated from selective splicing, which take part in many traits. Former investigation suggested that ci
Externí odkaz:
https://doaj.org/article/229af0bc9e2148e582a5e93e6b888847
Publikováno v:
PeerJ, Vol 12, p e17842 (2024)
Background Ferroptosis is a non-apoptotic iron-dependent form of cell death implicated in various cancer pathologies. However, its precise role in tumor growth and progression of cervical cancer (CC) remains unclear. Transferrin receptor protein 1 (T
Externí odkaz:
https://doaj.org/article/0c4c462f35af4c42a8154218e3bdf6f0
Autor:
Xunyu Zhou, Yida Wang, Xiaoyu Li, Jing Zhou, Wanyi Yang, Xin Wang, Sitong Jiao, Weibo Zuo, Ziming You, Wantao Ying, Chuanfang Wu, Jinku Bao
Publikováno v:
Redox Biology, Vol 73, Iss , Pp 103182- (2024)
Ferroptosis is an iron-dependent programmed cell death (PCD) enforced by lipid peroxidation accumulation. Transferrin receptor (TFRC), one of the signature proteins of ferroptosis, is abundantly expressed in hepatocellular carcinoma (HCC). However, p
Externí odkaz:
https://doaj.org/article/f70fd21b19d74d76bd8c39cbec048a1b
Autor:
Shuo Miao, Lanting Yang, Tao Xu, Zhantao Liu, Yixiao Zhang, Lin Ding, Wei Ding, Xiang Ao, Jianxun Wang
Publikováno v:
MedComm, Vol 5, Iss 6, Pp n/a-n/a (2024)
Abstract Iron overload is common in cardiovascular disease, it is also the factor that drives ferroptosis. Noncoding RNAs play an important role in heart disease; however, their regulatory role in iron overload‐mediated ferroptosis remains much unk
Externí odkaz:
https://doaj.org/article/8d307329b336417ba9f26c494929b23b
Publikováno v:
Redox Biology, Vol 72, Iss , Pp 103157- (2024)
Background: Doxorubicin (DOX) is a chemotherapeutic drug, while its clinical use is greatly limited by the life-threatening cardiotoxicity. N6-methyladenosine (m6A) RNA modification participates in varieties of cellular processes. Nonetheless, it rem
Externí odkaz:
https://doaj.org/article/360107e6bded4d67b7573551d9f4c5f6
Autor:
Runhua Tang, Haoran Wang, Jianyong Liu, Liuqi Song, Huimin Hou, Ming Liu, Jianye Wang, Jianlong Wang
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-16 (2024)
Abstract Background Bladder cancer is a common malignancy of the urinary system, and the survival rate and recurrence rate of patients with muscular aggressive (MIBC) bladder cancer are not ideal. Hypoxia is a pathological process in which cells acqu
Externí odkaz:
https://doaj.org/article/c49d82ba8ef34b2580377ee3c0075fab