Zobrazeno 1 - 10
of 59
pro vyhledávání: '"TF Westbrook"'
Autor:
AS Kashyap, Nataly Stylianou, Martin E. Gleave, Colleen C. Nelson, TF Westbrook, Anja Rockstroh, Brett G. Hollier, MC Sadowski, AT Fard, Melanie Lehman, Elizabeth D. Williams, R Buttyan, Ladan Fazli, C Wang, M Ward, Lidija Jovanovic, Jennifer H. Gunter
Publikováno v:
Oncology Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee588a1ba378f3439e48c7627e5e4519
https://doi.org/10.1530/oncolabs.1.p026
https://doi.org/10.1530/oncolabs.1.p026
Autor:
Tf. Westbrook, I. Migliaccio, CK Osborne, Maria F. Botero, Richard A. Gibbs, Earlene M. Schmitt, Stephen J. Elledge, SG Hilsenbeck, Ronald J. Bernardi, Jessica D. Kessler, Tingting Sun, Ca Shaw, D Wheeler, Don X. Nguyen, Rachel Schiff, Natalya N. Pavlova, Chad J. Creighton, Kristen L. Meerbrey
Publikováno v:
Cancer Research. 70:S6-10
Breast cancer is a collection of diseases with distinct clinical behaviors and underlying genetic causes. Triple-negative breast cancer (TNBC) is a common subtype of breast cancer that confers a particularly poor prognosis and is refractory to curren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b3d15147f489c3d3d6e9fd6c783e6c9
https://doi.org/10.1158/0008-5472.sabcs10-s6-10
https://doi.org/10.1158/0008-5472.sabcs10-s6-10
Autor:
Xu L; Department of Experimental Therapeutics, James P. Allison Institute, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA., Peng F; Department of Molecular and Cellular Biology, Lester and Sue Smith Breast Center, Dun L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Luo Q; Department of Experimental Therapeutics, James P. Allison Institute, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA., Ding Y; Department of Experimental Therapeutics, James P. Allison Institute, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA., Yuan F; Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030, USA., Zheng L; Therapeutic Innovation Center (THINC), and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., He W; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Zhang SS; Department of Chemistry, Rice University, Houston, TX 77005, USA., Fu X; Department of Pathology, Xijing Hospital, Xi'an, Shaanxi 710032, China., Liu J; Department of Pathology, Xijing Hospital, Xi'an, Shaanxi 710032, China., Mutlu AS; Therapeutic Innovation Center (THINC), and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Wang S; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Nehring RB; Therapeutic Innovation Center (THINC), and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Li X; College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan 611130, China., Tang Q; College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan 611130, China., Li C; Department of Experimental Therapeutics, James P. Allison Institute, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA., Lv X; Department of Experimental Therapeutics, James P. Allison Institute, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA., Dobrolecki LE; Department of Molecular and Cellular Biology, Lester and Sue Smith Breast Center, Dun L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Zhang W; Department of Molecular and Cellular Biology, Lester and Sue Smith Breast Center, Dun L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Han D; Department of Molecular and Cellular Biology, Lester and Sue Smith Breast Center, Dun L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Zhao N; Department of Molecular and Cellular Biology, Lester and Sue Smith Breast Center, Dun L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Jaehnig E; Department of Molecular and Cellular Biology, Lester and Sue Smith Breast Center, Dun L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Wang J; Department of Molecular and Cellular Biology, Lester and Sue Smith Breast Center, Dun L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Wu W; Department of Experimental Therapeutics, James P. Allison Institute, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA., Graham DA; Department of Molecular and Cellular Biology, Lester and Sue Smith Breast Center, Dun L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Li Y; Therapeutic Innovation Center (THINC), and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Chen R; Therapeutic Innovation Center (THINC), and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Peng W; Department of Biology and Biochemistry, University of Houston, Houston, TX 77204, USA., Chen Y; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Catic A; Department of Molecular and Cellular Biology, Lester and Sue Smith Breast Center, Dun L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Zhang Z; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Zhang B; Department of Molecular and Cellular Biology, Lester and Sue Smith Breast Center, Dun L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Mustoe AM; Therapeutic Innovation Center (THINC), and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Koong AC; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Miles G; Department of Molecular and Cellular Biology, Lester and Sue Smith Breast Center, Dun L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Lewis MT; Department of Molecular and Cellular Biology, Lester and Sue Smith Breast Center, Dun L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Wang MC; HHMI Janelia Research Campus, Ashburn, VA 20147, USA., Rosenberg SM; Therapeutic Innovation Center (THINC), and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., O'Malley BW; Department of Molecular and Cellular Biology, Lester and Sue Smith Breast Center, Dun L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Westbrook TF; Therapeutic Innovation Center (THINC), and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Xu H; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Zhang XH; Department of Molecular and Cellular Biology, Lester and Sue Smith Breast Center, Dun L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Osborne CK; Department of Molecular and Cellular Biology, Lester and Sue Smith Breast Center, Dun L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Li JB; Department of Genetics, Stanford University, Stanford, CA 94305, USA., Ellis MJ; Department of Molecular and Cellular Biology, Lester and Sue Smith Breast Center, Dun L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Rimawi MF; Department of Molecular and Cellular Biology, Lester and Sue Smith Breast Center, Dun L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Rosen JM; Department of Molecular and Cellular Biology, Lester and Sue Smith Breast Center, Dun L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Chen X; Department of Experimental Therapeutics, James P. Allison Institute, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA; Department of Molecular and Cellular Biology, Lester and Sue Smith Breast Center, Dun L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address: xchen23@mdanderson.org.
Publikováno v:
Cell [Cell] 2024 Oct 14. Date of Electronic Publication: 2024 Oct 14.
Autor:
Meena JK; Therapeutic Innovation Center (THINC), Baylor College of Medicine, Houston, Texas.; Verna & Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, Texas., Wang JH; Verna & Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, Texas.; Medical Scientist Training Program, Baylor College of Medicine, Houston, Texas., Neill NJ; Therapeutic Innovation Center (THINC), Baylor College of Medicine, Houston, Texas.; Verna & Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, Texas.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas., Keough D; The School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Australia., Putluri N; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas., Katsonis P; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas., Koire AM; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas., Lee H; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Bowling EA; Therapeutic Innovation Center (THINC), Baylor College of Medicine, Houston, Texas.; Verna & Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, Texas., Tyagi S; Verna & Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, Texas., Orellana M; Verna & Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, Texas., Dominguez-Vidaña R; Verna & Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, Texas., Li H; Verna & Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, Texas., Eagle K; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas., Danan C; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas., Chung HC; Verna & Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, Texas., Yang AD; Therapeutic Innovation Center (THINC), Baylor College of Medicine, Houston, Texas.; Verna & Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, Texas.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas.; Medical Scientist Training Program, Baylor College of Medicine, Houston, Texas., Wu W; Verna & Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, Texas.; Medical Scientist Training Program, Baylor College of Medicine, Houston, Texas., Kurley SJ; Verna & Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, Texas., Ho BM; Verna & Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, Texas.; Medical Scientist Training Program, Baylor College of Medicine, Houston, Texas., Zoeller JR; Therapeutic Innovation Center (THINC), Baylor College of Medicine, Houston, Texas.; Verna & Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, Texas.; Medical Scientist Training Program, Baylor College of Medicine, Houston, Texas., Olson CM; Therapeutic Innovation Center (THINC), Baylor College of Medicine, Houston, Texas.; Verna & Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, Texas., Meerbrey KL; Therapeutic Innovation Center (THINC), Baylor College of Medicine, Houston, Texas.; Verna & Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, Texas., Lichtarge O; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas., Sreekumar A; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas., Dacso CC; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas., Guddat LW; The School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Australia., Rejman D; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czech Republic., Hocková D; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czech Republic., Janeba Z; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czech Republic., Simon LM; Therapeutic Innovation Center (THINC), Baylor College of Medicine, Houston, Texas., Lin CY; Therapeutic Innovation Center (THINC), Baylor College of Medicine, Houston, Texas.; Verna & Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, Texas.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas.; Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, Texas., Pillon MC; Therapeutic Innovation Center (THINC), Baylor College of Medicine, Houston, Texas.; Verna & Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, Texas., Westbrook TF; Therapeutic Innovation Center (THINC), Baylor College of Medicine, Houston, Texas.; Verna & Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, Texas.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas.; Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, Texas.
Publikováno v:
Cancer discovery [Cancer Discov] 2024 Sep 04; Vol. 14 (9), pp. 1699-1716.
Autor:
Bouguenina H, Nicolaou S, Bihan YL, Bowling EA, Calderon C, Caldwell JJ, Harrington B, Hayes A, McAndrew PC, Mitsopoulos C, Sialana FJ, Scarpino A, Stubbs M, Thapaliya A, Tyagi S, Wang HZ, Wood F, Burke R, Raynaud F, Choudhary J, van Montfort RLM, Sadok A, Westbrook TF, Collins I, Chopra R
Publikováno v:
IScience [iScience] 2024 Apr 14; Vol. 27 (5), pp. 109727. Date of Electronic Publication: 2024 Apr 14 (Print Publication: 2024).
Autor:
Bouguenina H; Centre for Cancer Drug Discovery, the Institute of Cancer Research, 15 Cotswold Road, Sutton, London SM2 5NG, UK., Nicolaou S; Centre for Cancer Drug Discovery, the Institute of Cancer Research, 15 Cotswold Road, Sutton, London SM2 5NG, UK., Le Bihan YV; Centre for Cancer Drug Discovery, the Institute of Cancer Research, 15 Cotswold Road, Sutton, London SM2 5NG, UK., Bowling EA; Therapeutic Innovation Centre (THINC), Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA., Calderon C; Therapeutic Innovation Centre (THINC), Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA., Caldwell JJ; Centre for Cancer Drug Discovery, the Institute of Cancer Research, 15 Cotswold Road, Sutton, London SM2 5NG, UK., Harrington B; Therapeutic Innovation Centre (THINC), Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA., Hayes A; Centre for Cancer Drug Discovery, the Institute of Cancer Research, 15 Cotswold Road, Sutton, London SM2 5NG, UK., McAndrew PC; Centre for Cancer Drug Discovery, the Institute of Cancer Research, 15 Cotswold Road, Sutton, London SM2 5NG, UK., Mitsopoulos C; Centre for Cancer Drug Discovery, the Institute of Cancer Research, 15 Cotswold Road, Sutton, London SM2 5NG, UK., Sialana FJ; Centre for Cancer Drug Discovery, the Institute of Cancer Research, 15 Cotswold Road, Sutton, London SM2 5NG, UK.; Functional Proteomics Group, The Institute of Cancer Research, Chester Beatty Laboratories, London SW3 6JB, UK., Scarpino A; Centre for Cancer Drug Discovery, the Institute of Cancer Research, 15 Cotswold Road, Sutton, London SM2 5NG, UK., Stubbs M; Centre for Cancer Drug Discovery, the Institute of Cancer Research, 15 Cotswold Road, Sutton, London SM2 5NG, UK., Thapaliya A; Centre for Cancer Drug Discovery, the Institute of Cancer Research, 15 Cotswold Road, Sutton, London SM2 5NG, UK., Tyagi S; Therapeutic Innovation Centre (THINC), Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA., Wang HZ; Centre for Cancer Drug Discovery, the Institute of Cancer Research, 15 Cotswold Road, Sutton, London SM2 5NG, UK., Wood F; Centre for Cancer Drug Discovery, the Institute of Cancer Research, 15 Cotswold Road, Sutton, London SM2 5NG, UK., Burke R; Centre for Cancer Drug Discovery, the Institute of Cancer Research, 15 Cotswold Road, Sutton, London SM2 5NG, UK., Raynaud F; Centre for Cancer Drug Discovery, the Institute of Cancer Research, 15 Cotswold Road, Sutton, London SM2 5NG, UK., Choudhary J; Functional Proteomics Group, The Institute of Cancer Research, Chester Beatty Laboratories, London SW3 6JB, UK., van Montfort RLM; Centre for Cancer Drug Discovery, the Institute of Cancer Research, 15 Cotswold Road, Sutton, London SM2 5NG, UK., Sadok A; Centre for Cancer Drug Discovery, the Institute of Cancer Research, 15 Cotswold Road, Sutton, London SM2 5NG, UK., Westbrook TF; Therapeutic Innovation Centre (THINC), Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA., Collins I; Centre for Cancer Drug Discovery, the Institute of Cancer Research, 15 Cotswold Road, Sutton, London SM2 5NG, UK., Chopra R; Centre for Cancer Drug Discovery, the Institute of Cancer Research, 15 Cotswold Road, Sutton, London SM2 5NG, UK.
Publikováno v:
IScience [iScience] 2023 Jun 07; Vol. 26 (7), pp. 107059. Date of Electronic Publication: 2023 Jun 07 (Print Publication: 2023).
Autor:
Ramabadran R; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX, USA.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.; Interdepartmental Program in Integrative Molecular and Biomedical Sciences, Baylor College of Medicine, Houston, TX, USA., Wang JH; Medical Scientist Training Program, Baylor College of Medicine, Houston, TX, USA.; Verna & Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX, USA., Reyes JM; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX, USA.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA., Guzman AG; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX, USA.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA., Gupta S; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX, USA.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA., Rosas C; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX, USA.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA., Brunetti L; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX, USA., Gundry MC; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX, USA.; Medical Scientist Training Program, Baylor College of Medicine, Houston, TX, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA., Tovy A; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX, USA.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA., Long H; Interdepartmental Program in Integrative Molecular and Biomedical Sciences, Baylor College of Medicine, Houston, TX, USA., Gu T; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX, USA.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA., Cullen SM; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX, USA.; Medical Scientist Training Program, Baylor College of Medicine, Houston, TX, USA., Tyagi S; Verna & Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA., Rux D; Lillehei Heart Institute and Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA., Kim JJ; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX, USA., Kornblau SM; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Kyba M; Lillehei Heart Institute and Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA., Stossi F; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA., Rau RE; Department of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston, TX, USA., Takahashi K; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Westbrook TF; Verna & Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.; Therapeutic Innovation Center, Baylor College of Medicine, Houston, TX, USA., Goodell MA; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX, USA. goodell@bcm.edu.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA. goodell@bcm.edu.
Publikováno v:
Nature cell biology [Nat Cell Biol] 2023 Apr; Vol. 25 (4), pp. 528-539. Date of Electronic Publication: 2023 Apr 06.
Human WDR5 promotes breast cancer growth and metastasis via KMT2-independent translation regulation.
Autor:
Cai WL; Hillman Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, United States.; Department of Pathology, Yale University, New Haven, United States., Chen JF; Department of Pathology, Yale University, New Haven, United States., Chen H; Department of Pathology, Yale University, New Haven, United States., Wingrove E; Department of Pathology, Yale University, New Haven, United States., Kurley SJ; Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, United States., Chan LH; Department of Pathology, Yale University, New Haven, United States., Zhang M; Department of Pathology, Yale University, New Haven, United States., Arnal-Estape A; Department of Pathology, Yale University, New Haven, United States.; Yale Cancer Center, Yale School of Medicine, New Haven, United States., Zhao M; Department of Pathology, Yale University, New Haven, United States., Balabaki A; Department of Pathology, Yale University, New Haven, United States., Li W; Yale Cancer Biology Institute, Department of Pharmacology, Yale University, West Haven, United States., Yu X; Mount Sinai Center for Therapeutics Discovery, Icahn School of Medicine at Mount Sinai, New York, United States.; Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, United States., Krop ED; Department of Pathology, Yale University, New Haven, United States.; Department of Biosciences, Rice University,, Houston, United States., Dou Y; Department of Pathology, University of Michigan, Ann Arbor, Ann Arbor, United States.; Department of Medicine, Department of Biochemistry and Molecular Medicine, University of Southern California, Los Angeles, United States., Liu Y; Yale Cancer Center, Yale School of Medicine, New Haven, United States.; Yale Cancer Biology Institute, Department of Pharmacology, Yale University, West Haven, United States., Jin J; Mount Sinai Center for Therapeutics Discovery, Icahn School of Medicine at Mount Sinai, New York, United States.; Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, United States., Westbrook TF; Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, United States., Nguyen DX; Department of Pathology, Yale University, New Haven, United States.; Yale Cancer Center, Yale School of Medicine, New Haven, United States.; Yale Stem Cell Center, Yale School of Medicine, New Haven, United States.; Department of Internal Medicine (Section of Medical Oncology), Yale School of Medicine,, New Haven, United States., Yan Q; Department of Pathology, Yale University, New Haven, United States.; Yale Cancer Center, Yale School of Medicine, New Haven, United States.; Yale Stem Cell Center, Yale School of Medicine, New Haven, United States.; Yale Center for Immuno-Oncology, Yale School of Medicine, New Haven, United States.
Publikováno v:
ELife [Elife] 2022 Aug 31; Vol. 11. Date of Electronic Publication: 2022 Aug 31.
Autor:
Gao Y; Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.; Dan L. Duncan Cancer Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.; Lester and Sue Smith Breast Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Kabotyanski EB; Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.; Dan L. Duncan Cancer Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Shepherd JH; The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Villegas E; University of Houston-Downtown, Houston, TX 77002, USA., Acosta D; Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.; Dan L. Duncan Cancer Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Hamor C; Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.; Dan L. Duncan Cancer Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Sun T; Dan L. Duncan Cancer Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.; Verna & Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Montmeyor-Garcia C; Canadian Blood Services, Toronto, ON M5G 2M1, Canada., He X; The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Dobrolecki LE; Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.; Dan L. Duncan Cancer Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.; Lester and Sue Smith Breast Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Westbrook TF; Dan L. Duncan Cancer Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.; Verna & Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Lewis MT; Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.; Dan L. Duncan Cancer Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.; Lester and Sue Smith Breast Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Hilsenbeck SG; Dan L. Duncan Cancer Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.; Lester and Sue Smith Breast Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Zhang XH; Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.; Dan L. Duncan Cancer Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.; Lester and Sue Smith Breast Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.; McNair Medical Institute, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Perou CM; The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Rosen JM; Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.; Dan L. Duncan Cancer Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
Publikováno v:
Cancer research communications [Cancer Res Commun] 2021 Dec; Vol. 1 (3), pp. 178-193. Date of Electronic Publication: 2021 Dec 27.
ZFTA-RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma.
Autor:
Arabzade A; Department of Chemical and Biomolecular Engineering, Rice University, Houston, Texas.; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas.; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas., Zhao Y; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas.; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas., Varadharajan S; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas.; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas., Chen HC; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas.; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas.; Cancer and Cell Biology Program, Baylor College of Medicine, Dan L. Duncan Cancer Center, Houston, Texas., Jessa S; Quantitative Life Sciences, McGill University, Montreal, Quebec, Canada., Rivas B; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas.; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas., Stuckert AJ; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas.; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas., Solis M; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas.; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas.; Cancer and Cell Biology Program, Baylor College of Medicine, Dan L. Duncan Cancer Center, Houston, Texas., Kardian A; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas.; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas.; Cancer and Cell Biology Program, Baylor College of Medicine, Dan L. Duncan Cancer Center, Houston, Texas., Tlais D; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas.; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas., Golbourn BJ; Department of Neurological Surgery, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Stanton AJ; Department of Neurological Surgery, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Chan YS; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas.; Department of Molecular and Cellular Biology and Center for Precision Environmental Health, Baylor College of Medicine, Houston, Texas.; Department of Bioengineering, Rice University, Houston, Texas.; Center for Cancer Epigenetics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Olson C; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas.; Department of Biochemistry and Molecular Biology, Houston, Texas., Karlin KL; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas.; Department of Biochemistry and Molecular Biology, Houston, Texas., Kong K; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas., Kupp R; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, England.; Department of Oncology, University of Cambridge, Hutchison/MRC Research Centre, Cambridge Biomedical Campus, Cambridge, England., Hu B; Department of Neurological Surgery, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Injac SG; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas.; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas., Ngo M; Department of Chemical and Biomolecular Engineering, Rice University, Houston, Texas., Wang PR; Department of Chemical and Biomolecular Engineering, Rice University, Houston, Texas., De León LA; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas., Sahm F; Hopp-Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Neuropathology, Heidelberg University Hospital, Heidelberg, Germany., Kawauchi D; Hopp-Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Biochemistry and Cellular Biology, National Center of Neurology and Psychiatry (NCNP), Tokyo, Japan., Pfister SM; Hopp-Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.; Department of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.; Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, Heidelberg, Germany., Lin CY; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas., Hodges HC; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas.; Department of Molecular and Cellular Biology and Center for Precision Environmental Health, Baylor College of Medicine, Houston, Texas.; Department of Bioengineering, Rice University, Houston, Texas.; Center for Cancer Epigenetics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Singh I; Department of Molecular and Cellular Medicine, College of Medicine, Texas A&M University Health Science Center, Bryan, Texas., Westbrook TF; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas.; Department of Biochemistry and Molecular Biology, Houston, Texas., Chintagumpala MM; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas., Blaney SM; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas., Parsons DW; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas., Pajtler KW; Hopp-Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.; Department of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.; Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, Heidelberg, Germany., Agnihotri S; Department of Neurological Surgery, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Gilbertson RJ; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, England.; Department of Oncology, University of Cambridge, Hutchison/MRC Research Centre, Cambridge Biomedical Campus, Cambridge, England., Yi J; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas.; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas., Jabado N; Quantitative Life Sciences, McGill University, Montreal, Quebec, Canada.; Department of Human Genetics, McGill University, Montreal, Quebec, Canada., Kleinman CL; Quantitative Life Sciences, McGill University, Montreal, Quebec, Canada.; Department of Human Genetics, McGill University, Montreal, Quebec, Canada.; Lady Davis Research Institute, Jewish General Hospital, Quebec, Canada., Bertrand KC; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas. stephen.mack@stjude.org deneen@bcm.edu stephen.mack@stjude.org.; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas., Deneen B; Cancer and Cell Biology Program, Baylor College of Medicine, Dan L. Duncan Cancer Center, Houston, Texas. stephen.mack@stjude.org deneen@bcm.edu stephen.mack@stjude.org.; Program in Developmental Biology, Baylor College of Medicine, Houston, Texas.; Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, Texas.; Department of Neurosurgery, Baylor College of Medicine, Houston, Texas., Mack SC; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas. stephen.mack@stjude.org deneen@bcm.edu stephen.mack@stjude.org.; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas.; Cancer and Cell Biology Program, Baylor College of Medicine, Dan L. Duncan Cancer Center, Houston, Texas.
Publikováno v:
Cancer discovery [Cancer Discov] 2021 Sep; Vol. 11 (9), pp. 2200-2215. Date of Electronic Publication: 2021 Mar 19.