Zobrazeno 1 - 10
of 229
pro vyhledávání: '"TETSUSHI FURUKAWA"'
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
BackgroundSacubitril/valsartan (SacVal) has been shown to improve the prognosis of heart failure; however, whether SacVal reduces the occurrence of atrial fibrillation (AF) in heart failure has not yet been elucidated. In this study, we aimed to dete
Externí odkaz:
https://doaj.org/article/7134f062c72f4541b70146a9c8fe7734
Autor:
Katsushige Ono, Yu‐ki Iwasaki, Masaharu Akao, Takanori Ikeda, Kuniaki Ishii, Yasuya Inden, Kengo Kusano, Yoshinori Kobayashi, Yukihiro Koretsune, Tetsuo Sasano, Naokata Sumitomo, Naohiko Takahashi, Shinichi Niwano, Nobuhisa Hagiwara, Ichiro Hisatome, Tetsushi Furukawa, Haruo Honjo, Toru Maruyama, Yuji Murakawa, Masahiro Yasaka, Eiichi Watanabe, Takeshi Aiba, Mari Amino, Hideki Itoh, Hisashi Ogawa, Yasuo Okumura, Chizuko Aoki‐Kamiya, Jun Kishihara, Eitaro Kodani, Takashi Komatsu, Yusuke Sakamoto, Kazuhiro Satomi, Tsuyoshi Shiga, Tetsuji Shinohara, Atsushi Suzuki, Shinya Suzuki, Yukio Sekiguchi, Satoshi Nagase, Noriyuki Hayami, Masahide Harada, Tadashi Fujino, Takeru Makiyama, Mitsunori Maruyama, Junichiro Miake, Shota Muraji, Hiroshige Murata, Norishige Morita, Hisashi Yokoshiki, Koichiro Yoshioka, Kenji Yodogawa, Hiroshi Inoue, Ken Okumura, Takeshi Kimura, Hiroyuki Tsutsui, Wataru Shimizu, the Japanese Circulation Society and, Japanese Heart Rhythm Society Joint Working Group
Publikováno v:
Journal of Arrhythmia, Vol 38, Iss 6, Pp 833-973 (2022)
Externí odkaz:
https://doaj.org/article/bef7f80603e745898ce885e9dc78b98b
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0292118 (2023)
BackgroundAtrial fibrillation (AF) is the most common sustained arrhythmia, and it causes a high rate of complications such as stroke. It is known that AF begins as paroxysmal form and gradually progresses to persistent form, and sometimes it is diff
Externí odkaz:
https://doaj.org/article/3efe2515277a4f6fb7c4e1002490bba6
Autor:
Masahiro Yamazoe, Tetsuo Sasano, Kensuke Ihara, Kentaro Takahashi, Wakana Nakamura, Naomi Takahashi, Hiroaki Komuro, Satomi Hamada, Tetsushi Furukawa
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Systemic inflammation is assumed to be the consequence and the cause of atrial fibrillation (AF); however, the underlying mechanism remains unclear. We aimed to evaluate the level of cell-free DNA (cfDNA) in patients with AF and AF mimicking
Externí odkaz:
https://doaj.org/article/dc2b3b0c509c46918edf0a33c32ae542
Autor:
Jiyoung Lee, Akito Sutani, Rin Kaneko, Jun Takeuchi, Tetsuo Sasano, Takashi Kohda, Kensuke Ihara, Kentaro Takahashi, Masahiro Yamazoe, Tomohiro Morio, Tetsushi Furukawa, Fumitoshi Ishino
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Our understanding of the development of the heart has been limited by a lack of in vitro cellular models. Here, the authors treat mouse embryonic stem cell-derived embryoid bodies with laminin-entactin (to mimic the developing microenvironment) and F
Externí odkaz:
https://doaj.org/article/6e0a5c1a58564f4ca225428e30d3056d
Autor:
Masami Kodama, Kazuharu Furutani, Reiko Kimura, Tomoko Ando, Kazuho Sakamoto, Shushi Nagamori, Takashi Ashihara, Yoshihisa Kurachi, Yuko Sekino, Tetsushi Furukawa, Yasunari Kanda, Junko Kurokawa
Publikováno v:
Journal of Pharmacological Sciences, Vol 140, Iss 4, Pp 325-330 (2019)
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are a valuable tool to characterize the pharmacology and toxic effects of drugs on heart cells. In particular, hiPSC-CMs can be used to identify drugs that generate arrhythmias. H
Externí odkaz:
https://doaj.org/article/fc79714f52eb4882b9cfedf40d5e005d
Autor:
Yusuke Ebana, Tetsushi Furukawa
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 22, Iss , Pp 150-153 (2019)
Atrial fibrillation (AF) can be initiated from arrhythmogenic foci within the muscular sleeves that extend not only into the pulmonary veins but also into both vena cavae. Patients with SVC-derived AF have the common clinical and genetic risk factors
Externí odkaz:
https://doaj.org/article/ed753a590db3446daa0b1c5944e26c92
Autor:
Masao Takeuchi, Kikuko Takeuchi, Tomoyo Takai, Ritsuko Yamaguchi, Tetsushi Furukawa, Ken-Ichi Akagi, Jun K Takeuchi
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0226538 (2021)
Glypican-5 (GPC5) is a heparan sulfate proteoglycan (HSPG) localized to the plasma membrane. We previously reported that in the human mesenchymal stem cell line UE6E7T-3, GPC5 is overexpressed in association with transformation and promotes cell prol
Externí odkaz:
https://doaj.org/article/d3ba6654f8ca4b51822f78bacf81d4c4
Autor:
Yutaro Hori, Yoko Tanimoto, Satoru Takahashi, Tetsushi Furukawa, Kazuko Koshiba-Takeuchi, Jun K. Takeuchi
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-12 (2018)
Abstract Background Heart development is a relatively fragile process in which many transcription factor genes show dose-sensitive characteristics such as haploinsufficiency and lower penetrance. Despite efforts to unravel the genetic mechanism for o
Externí odkaz:
https://doaj.org/article/891f8cee6efc40ba9e3d471a0e049d67
Autor:
Min Li, Yasunari Kanda, Takashi Ashihara, Tetsuo Sasano, Yuji Nakai, Masami Kodama, Erina Hayashi, Yuko Sekino, Tetsushi Furukawa, Junko Kurokawa
Publikováno v:
Journal of Pharmacological Sciences, Vol 134, Iss 2, Pp 75-85 (2017)
Human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes hold great potentials to predict pro-arrhythmic risks in preclinical cardiac safety screening, although the hiPSC cardiomyocytes exhibit rather immature functional and structural char
Externí odkaz:
https://doaj.org/article/07aceca9b16b42c88b263a8e009073ce