Zobrazeno 1 - 10
of 1 830
pro vyhledávání: '"TERT promoter mutations"'
Autor:
Maria Lina Tornesello, Andrea Cerasuolo, Noemy Starita, Sara Amiranda, Patrizia Bonelli, Franca Maria Tuccillo, Franco M. Buonaguro, Luigi Buonaguro, Anna Lucia Tornesello
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Telomerase activity and telomere elongation are essential conditions for the unlimited proliferation of neoplastic cells. Point mutations in the core promoter region of the telomerase reverse transcriptase (TERT) gene have been found to occur at high
Externí odkaz:
https://doaj.org/article/c9a4880c0bec4b85b71cf7cd8dd88e34
Autor:
Noha Mukhtar, Kheloud Alhamoudi, Meshael Alswailem, Hindi Alhindi, Avaniyapuram Kannan Murugan, Balgees Alghamdi, Ali S. Alzahrani
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
ContextThe American Thyroid Association risk stratification (ATA) and the American Joint Committee on Cancer Tumor Node Metastases (TNM) predict recurrence and mortality of differentiated thyroid cancer (DTC). BRAFV600E and TERT promoter mutations ha
Externí odkaz:
https://doaj.org/article/5232a9ffc04842498454d08cc7ea81d2
Autor:
Hui Zhang, Xiao-Jing Ma, Xue-Ping Xiang, Qi-Yuan Wang, Jin-Long Tang, Xiao-Yan Yu, Jing-Hong Xu
Publikováno v:
Current Oncology, Vol 30, Iss 2, Pp 2405-2416 (2023)
Purpose: Pleomorphic xanthoastrocytoma (PXA) is an uncommon astrocytoma that tends to occur in children and young adults and has a relatively favorable prognosis. The 2021 WHO classification of tumors of the central nervous system (CNS WHO), 5th edit
Externí odkaz:
https://doaj.org/article/0f390da6144b4a78a378ab684f2c71bb
Autor:
Leyla Blanco-García, Yolanda Ruano, Raquel Blanco Martínez-Illescas, Rocío Cubo, Paula Jiménez Sánchez, Víctor J. Sánchez-Arévalo Lobo, Erica Riveiro Falkenbach, Pablo Ortiz Romero, María C. Garrido, José L. Rodríguez Peralto
Publikováno v:
Heliyon, Vol 9, Iss 8, Pp e18953- (2023)
Melanoma is the most aggressive form of skin cancer and the leading cause of death from cutaneous tumors. Several studies have associated alterations in the TERT promoter region (pTERT) with gene overexpression, aggressiveness and poor prognosis of t
Externí odkaz:
https://doaj.org/article/5fabe54c1f8245bfb8a824dfbf773c29
Autor:
Yaying Du, Shu Zhang, Gang Zhang, Jiaying Hu, Lianhua Zhao, Yuanyuan Xiong, Lu Shen, Rongrong Chen, Ke Ye, Yan Xu
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundThe incidence of thyroid cancer in China has rapidly increased in recent decades. As the genetic profiles of thyroid cancer vary dramatically between different geographical regions, a comprehensive genetic landscape of thyroid cancer in the
Externí odkaz:
https://doaj.org/article/d64102ee89f24e75b143a50f31a89937
Publikováno v:
Journal of Hepatocellular Carcinoma, Vol Volume 9, Pp 1201-1215 (2022)
Haibin Zhang,1 Xiaolu Zhang,1 Jingya Yu2 1Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, People’s Republic of China; 2Department of Diagnost
Externí odkaz:
https://doaj.org/article/d9d2fb17588548f0aeae0a9ab3653699
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 11, Pp n/a-n/a (2022)
Abstract Background Telomerase is a ribonucleoprotein complex consisting of a catalytic component telomerase reverse transcriptase (TERT), internal RNA template and other co‐factors, and its essential function is to synthesize telomeric DNA, repeti
Externí odkaz:
https://doaj.org/article/b0d830773b1d40fc841554f37c804a11
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Autor:
Francesca Lessi, Mariangela Morelli, Sara Franceschi, Paolo Aretini, Michele Menicagli, Andrea Marranci, Francesco Pasqualetti, Carlo Gambacciani, Francesco Pieri, Gianluca Grimod, Vanna Zucchi, Samanta Cupini, Anna Luisa Di Stefano, Orazio Santo Santonocito, Chiara Maria Mazzanti
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 10147 (2023)
Circulating tumor cells (CTCs) are one of the most important causes of tumor recurrence and distant metastases. Glioblastoma (GBM) has been considered restricted to the brain for many years. Nevertheless, in the past years, several pieces of evidence
Externí odkaz:
https://doaj.org/article/d16d19be41cd4c579ac828fde9d0c6de
Publikováno v:
OncoTargets and Therapy, Vol Volume 14, Pp 2741-2746 (2021)
Lin Gui,1 Shaoyan Liu,2 Ye Zhang,3 Yuankai Shi1 1Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing Key Labo
Externí odkaz:
https://doaj.org/article/10f1209b7ce4440ead4cfd6189e07a89