Zobrazeno 1 - 10
of 617
pro vyhledávání: '"TERC"'
Autor:
Mandisa Mbeje, Jeyalakshmi Kandhavelu, Clement Penny, Mmamoletla Kgoebane-Maseko, Zodwa Dlamini, Rahaba Marima
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 9, Pp 7257-7274 (2023)
Prostate cancer (PCa) is the leading cancer in men globally. The association between PCa and long non-coding RNAs (lncRNAs) has been reported. Aberrantly expressed lncRNAs have been documented in each of the cancer “hallmarks”. Androgen signaling
Externí odkaz:
https://doaj.org/article/3c09fe3d8ace4347ac1d03fdbd157a52
Autor:
Mohamed Bakr, Mai A. Abd-Elmawla, Hanan Elimam, Hebatallah Gamal El-Din, Amal Fawzy, Ahmed I. Abulsoud, Sherine M. Rizk
Publikováno v:
Non-coding RNA Research, Vol 8, Iss 3, Pp 302-314 (2023)
Aim: Long non-coding RNA (LncRNA) telomerase RNA component (TERC) has telomerase-dependent and independent activity in numerous cancer types. The present study purposes to demonstrate the role of lncRNA TERC as a diagnostic serum biomarker in colorec
Externí odkaz:
https://doaj.org/article/32971c03c80f463da5ef881e8d098a04
Publikováno v:
Biology of Sex Differences, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Background Clear cell renal cell carcinoma (ccRCC) displays sex-biased incidence, outcomes, molecular alterations and treatment efficacy; however, clinical managements are largely identical in male and female patients. Moreover, many biomark
Externí odkaz:
https://doaj.org/article/4778c05e533a47f4b32da7b57de2b53b
Publikováno v:
Open Medicine, Vol 18, Iss 1, Pp 1031-45 (2023)
This study investigated the function of telomerase RNA component (TERC) in spinal cord injury (SCI). SCI models were established in rats via laminectomy and PC-12 cells were treated with lipopolysaccharide (LPS). TERC and miR-34a-5p expressions in ce
Externí odkaz:
https://doaj.org/article/e08cfac2ac5d49e895f34ef4cd739cf4
Autor:
Jing Wang, Mingkai Dai, Xiangling Xing, Xing Wang, Xin Qin, Tao Huang, Zhiqing Fang, Yidong Fan, Dawei Xu
Publikováno v:
Molecular Oncology, Vol 17, Iss 1, Pp 150-172 (2023)
Telomerase activation is required for malignant transformation. Recent advances in high‐throughput technologies have enabled the generation of complex datasets, thus providing alternative approaches to exploring telomerase biology more comprehensiv
Externí odkaz:
https://doaj.org/article/d36c388e58034e61845a262802e40a69
Akademický článek
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Akademický článek
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Autor:
Radwa Sharaf, Meagan Montesion, Julia F. Hopkins, Jiarong Song, Garrett M. Frampton, Lee A. Albacker
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-15 (2022)
Abstract Background Cancer cells can proliferate indefinitely through telomere maintenance mechanisms. These mechanisms include telomerase-dependent elongation, mediated by TERT activation, and alternative lengthening of telomeres (ALT), linked to lo
Externí odkaz:
https://doaj.org/article/6fb42aa215fa4eadac435596e5d8a55d
Autor:
Cristina Montero‐Conde, Luis Javier Leandro‐García, Ángel M. Martínez‐Montes, Paula Martínez, Francisco J. Moya, Rocío Letón, Eduardo Gil, Natalia Martínez‐Puente, Sonsoles Guadalix, Maria Currás‐Freixes, Laura García‐Tobar, Carles Zafon, Mireia Jordà, Garcilaso Riesco‐Eizaguirre, Patricia González‐García, María Monteagudo, Rafael Torres‐Pérez, Veronika Mancikova, Sergio Ruiz‐Llorente, Manuel Pérez‐Martínez, Guillermo Pita, Juan Carlos Galofré, Anna Gonzalez‐Neira, Alberto Cascón, Cristina Rodríguez‐Antona, Diego Megías, María A. Blasco, Eduardo Caleiras, Sandra Rodríguez‐Perales, Mercedes Robledo
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 8, Pp n/a-n/a (2022)
Background Comprehensive molecular studies on tumours are needed to delineate immortalization process steps and identify sensitive prognostic biomarkers in thyroid cancer. Methods and Results In this study, we extensively characterize telomere‐rela
Externí odkaz:
https://doaj.org/article/50de3fcc7b624a41bff4004a50893619
Akademický článek
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