Compression of amorphous solid dispersions prepared by hot-melt extrusion, spray drying and vacuum drum drying

Autor: Barbara V. Schönfeld, Karl G. Wagner, Ulrich Westedt

Publikováno v: International Journal of Pharmaceutics: X, Vol 3, Iss, Pp 100102-(2021)
International Journal of Pharmaceutics: X

The present study explored vacuum drum drying (VDD) as an alternative technology for amorphous solid dispersions (ASDs) manufacture compared to hot-melt extrusion (HME) and spray drying (SD) focusing on downstream processability (powder properties, c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5652c30c962c4b6bc07f6e0b0690ee39
http://www.sciencedirect.com/science/article/pii/S2590156721000311

Compression of amorphous solid dispersions prepared by hot-melt extrusion, spray drying and vacuum drum drying.

Autor: Schönfeld BV; Department of Pharmaceutical Technology, University of Bonn, Gerhard-Domagk-Straße 3, 53121 Bonn, Germany.; AbbVie Deutschland GmbH & Co. KG, Knollstraße 50, 67061 Ludwigshafen, Germany., Westedt U; AbbVie Deutschland GmbH & Co. KG, Knollstraße 50, 67061 Ludwigshafen, Germany., Wagner KG; Department of Pharmaceutical Technology, University of Bonn, Gerhard-Domagk-Straße 3, 53121 Bonn, Germany.

Publikováno v: International journal of pharmaceutics: X [Int J Pharm X] 2021 Nov 03; Vol. 3, pp. 100102. Date of Electronic Publication: 2021 Nov 03 (Print Publication: 2021).