Zobrazeno 1 - 10
of 28
pro vyhledávání: '"TDF, tenofovir disoproxil fumarate"'
Publikováno v:
Acta Pharmaceutica Sinica B. 12:1567-1590
HIV reverse transcriptase (RT) inhibitors are the important components of highly active antiretroviral therapies (HAARTs) for anti-HIV treatment and pre-exposure prophylaxis in clinical practice. Many RT inhibitors and their combination regimens have
Autor:
Lauri Diehl, Becket Feierbach, Ricardo Ramirez, Neeru Bhardwaj, Jeffrey J. Wallin, Nicholas van Buuren, Scott Turner, Samuel Kim, Dmytro Kornyeyev, H.L. Chan, Abhishek Aggarwal, Patrick Marcellin, Maria Buti, Simon P. Fletcher, Vithika Suri, Hongmei Mo, Anuj Gaggar, Christina Moon, Li Li, Nam Bui, Diana Chen
Publikováno v:
JHEP Reports
Background & Aims We aim to describe the liver immune microenvironment by analyzing liver biopsies from patients with chronic HBV infection (CHB). Host immune cell signatures and their corresponding localization were characterized by analyzing the in
Autor:
George V. Papatheodoridis, Harry L.A. Janssen, Florian van Boemmel, Margarita Papatheodoridi, Anastasia Kourikou, Cihan Yurdaydin, Bettina E. Hansen, Pietro Lampertico, John Vlachogiannakos, Ramazan Idilman, Savvoula Savvidou, John Goulis, Marta López-Gómez, Spilios Manolakopoulos, Thomas Berg, Nikolaos K. Gatselis, Maria Buti, Jose Luis Calleja, Rafael Esteban, George N Dalekos, Rhea Veelken, Vana Sypsa, Kostas Galanis, Alessandro Loglio
Publikováno v:
JHEP Reports
JHEP Reports, Vol 3, Iss 3, Pp 100290-(2021)
Scientia
JHEP Reports, 3(3):100290. Elsevier
JHEP Reports, Vol 3, Iss 3, Pp 100290-(2021)
Scientia
JHEP Reports, 3(3):100290. Elsevier
Background & Aims Recently, several risk scores for prediction of hepatocellular carcinoma (HCC) were developed in cohorts of treated Asian patients with chronic hepatitis B (CHB), but they have not been assessed in non-Asian patients. We evaluated t
Autor:
David Shum, Seung Kew Yoon, Marc Peter Windisch, Soonju Park, Eva Zusinaite, Eunji Jo, Denis E. Kainov, Jaewon Yang, Pil Soo Sung, Alexander König
Publikováno v:
JHEP Reports
JHEP Reports, Vol 3, Iss 4, Pp 100296-(2021)
JHEP Reports, Vol 3, Iss 4, Pp 100296-(2021)
Background & Aims Chronic hepatitis B is an incurable disease. Addressing the unmet medical need for therapies has been hampered by a lack of suitable cell culture models to investigate the HBV life cycle in a single experimental setup. We sought to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2d39818aec9a96715b2a465ff2da762
https://hdl.handle.net/11250/3045132
https://hdl.handle.net/11250/3045132
Autor:
Grace Lai-Hung Wong, Vincent Wai-Sun Wong, Henry Lik-Yuen Chan, Hye Won Lee, Terry Cheuk-Fung Yip, Stephen L. Chan, Lilian Yan Liang, Hester Wing-Sum Luk, Vicki Wing-Ki Hui, Jimmy Che-To Lai, Yee-Kit Tse, Becky Wing-Yan Yuen
Publikováno v:
JHEP Reports
JHEP Reports, Vol 2, Iss 6, Pp 100152-(2020)
JHEP Reports, Vol 2, Iss 6, Pp 100152-(2020)
Background & Aims Antiviral treatment is known to improve survival in patients with chronic hepatitis B (CHB)-related hepatocellular carcinoma (HCC). Yet, the treatment uptake in CHB patients remains low. We aimed to report the secular trend in antiv
Autor:
Ching-Lung Lai, Wai-Kay Seto, James Fung, Danny Ka-Ho Wong, Gerald Tsz-Yau Wong, Man-Fung Yuen
Publikováno v:
JHEP Reports
JHEP Reports, Vol 2, Iss 3, Pp-(2020)
JHEP Reports, Vol 2, Iss 3, Pp-(2020)
Background & Aims Nucleos(t)ide analogues (NUCs) effectively suppress serum HBV DNA. Previously, we have identified 21 patients with undetectable covalently closed circular DNA (cccDNA) upon long-term NUC therapy. This study investigated the effect o
Akademický článek
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Akademický článek
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Autor:
Aggarwal A; Gilead Sciences, Foster City, CA, USA., Odorizzi PM; Gilead Sciences, Foster City, CA, USA., Brodbeck J; Gilead Sciences, Foster City, CA, USA., van Buuren N; Gilead Sciences, Foster City, CA, USA., Moon C; Gilead Sciences, Foster City, CA, USA., Chang S; Gilead Sciences, Foster City, CA, USA., Adona M; Gilead Sciences, Foster City, CA, USA., Suthram S; Gilead Sciences, Foster City, CA, USA., Suri V; Gilead Sciences, Foster City, CA, USA., Trowe T; Gilead Sciences, Foster City, CA, USA., Turner S; Gilead Sciences, Foster City, CA, USA., Marcellin P; Hôpital Beaujon, Clichy, France., Buti M; Hospital Universitario Valle Hebron, Barcelona, Spain., Gaggar A; Gilead Sciences, Foster City, CA, USA., Fletcher SP; Gilead Sciences, Foster City, CA, USA., Diehl L; Gilead Sciences, Foster City, CA, USA., Feierbach B; Gilead Sciences, Foster City, CA, USA., Balsitis S; Gilead Sciences, Foster City, CA, USA.
Publikováno v:
JHEP reports : innovation in hepatology [JHEP Rep] 2022 Dec 26; Vol. 5 (4), pp. 100664. Date of Electronic Publication: 2022 Dec 26 (Print Publication: 2023).
Autor:
Mitchell T; Institute of Liver Studies, King's College Hospital, London, United Kingdom.; Gastroenterology and Hepatology Department, Royal Perth Hospital, Perth, Australia., Nayagam JS; Institute of Liver Studies, King's College Hospital, London, United Kingdom.; Department of Inflammation Biology, King's College London, London, UK., Dusheiko G; Institute of Liver Studies, King's College Hospital, London, United Kingdom.; University College London Medical School, London, UK., Agarwal K; Institute of Liver Studies, King's College Hospital, London, United Kingdom.
Publikováno v:
JHEP reports : innovation in hepatology [JHEP Rep] 2022 Nov 04; Vol. 5 (2), pp. 100623. Date of Electronic Publication: 2022 Nov 04 (Print Publication: 2023).