Zobrazeno 1 - 10
of 19 297
pro vyhledávání: '"TCR - T cell receptor"'
Akademický článek
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Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
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Autor:
Ying Zhao, Lili Zhang, Limin Liu, Xuan Zhou, Fangfang Ding, Yan Yang, Shiyu Du, Hongmin Wang, Miranda Van Eck, Jun Wang
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 42(12)
Background: ABCA1 (ATP-binding cassette transporter A1) mediates cholesterol efflux to apo AI to maintain cellular cholesterol homeostasis. The current study aims to investigate whether T-cell–specific deletion of ABCA1 modulates the phenotype/func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2402b8c838fc1680f0d722d8453aadab
https://pubmed.ncbi.nlm.nih.gov/36252122
https://pubmed.ncbi.nlm.nih.gov/36252122
Autor:
Maya Haus-Cohen, Yoram Reiter
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The clinical success of cancer immunotherapy has driven ongoing efforts to identify novel targets that can effectively guide potent effector functions to eliminate malignant cells. Traditionally, immunotherapies have focused on surface antigens; howe
Externí odkaz:
https://doaj.org/article/503eee7d55634cd5a7d37e8ca0795a8c
Autor:
Terri V. Cornforth, Nathifa Moyo, Suzanne Cole, Emily P. S. Lam, Tatiana Lobry, Ron Wolchinsky, Angharad Lloyd, Katarzyna Ward, Eleanor M. Denham, Giulia Masi, Phyllis Tea Qing Yun, Colin Moore, Selsabil Dhaouadi, Gurdyal S. Besra, Natacha Veerapen, Patricia T. Illing, Julian P. Vivian, Jeremy M. Raynes, Jérôme Le Nours, Anthony W. Purcell, Samit Kundu, Jonathan D. Silk, Luke Williams, Sophie Papa, Jamie Rossjohn, Duncan Howie, Joseph Dukes
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundMajor histocompatibility complex class-1-related protein (MR1), unlike human leukocyte antigen (HLA) class-1, was until recently considered to be monomorphic. MR1 presents metabolites in the context of host responses to bacterial infection.
Externí odkaz:
https://doaj.org/article/8f539e9eaf5e40e19fbc3e2c06f07574
Publikováno v:
Stroke. 52(9)
Background and Purpose: T lymphocytes contribute to secondary brain damage after stroke. It has not been fully investigated whether this contribution is caused by antigen-specific or antigen-nonspecific activation of T lymphocytes. Lymphocytes from N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::729bcb8e26ace3e33e4a58c8e77dcedf
https://pubmed.ncbi.nlm.nih.gov/34266304
https://pubmed.ncbi.nlm.nih.gov/34266304
Autor:
Kohm, Adam P.1 (AUTHOR), Turley, Danielle M.1 (AUTHOR), Miller, Stephen D.1 (AUTHOR) s-d-miller@northwestern.edu
Publikováno v:
International Reviews of Immunology. Sep-Dec2005, Vol. 24 Issue 5/6, p361-392. 32p. 4 Diagrams.
Autor:
Abdullah Degirmencay, Sharyn Thomas, Angelika Holler, Samuel Burgess, Emma C. Morris, Hans J. Stauss
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The expression levels of TCRs on the surface of human T cells define the avidity of TCR-HLA/peptide interactions. In this study, we have explored which components of the TCR-CD3 complex are involved in determining the surface expression levels of TCR
Externí odkaz:
https://doaj.org/article/8025343ede7741d989be0574485bfd42
Autor:
Nadine M. Woessner, Simon M. Brandl, Sara Hartmann, Wolfgang W. Schamel, Frederike A. Hartl, Susana Minguet
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionAntigen binding to the T cell antigen receptor (TCR) leads to the phosphorylation of the immunoreceptor tyrosine-based activation motifs (ITAMs) of the CD3 complex, and thereby to T cell activation. The CD3ε subunit plays a unique role i
Externí odkaz:
https://doaj.org/article/0a1412bd5d8541f29df79e6652127bbd
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Non-mutated FVIII-specific CD4 T cell epitopes have been recently found to contribute to the development of inhibitors in patients with hemophilia A (HA), while auto-reactive CD4 T cells specific to FVIII circulate in the blood of healthy individuals
Externí odkaz:
https://doaj.org/article/73797c65c3b543d0848c1d94104098aa