PATHOGENIC VARIANTS IN THE NPM1 GENE IN PATIENTS WITH ACUTE MYELOID LEUKEMIA IN AMAZONAS STATE, BRAZIL

Autor: TCD Santos, GSP Braz, EN Assunção, MOD Santos, VC Costa, WO Azevedo, LNM Passos, AM Tarragô, LPS Mourão, GAV Silva

Publikováno v: Hematology, Transfusion and Cell Therapy, Vol 46, Iss , Pp S371-S372 (2024)

Background: Acute Myeloid Leukemia (AML) is a heterogeneous disease with different clinical and molecular manifestations, annually a disease with rates important of mortality. The AML is characterized by present genetic alterations, including variati

Externí odkaz: https://doaj.org/article/b2d6df00f9fe4e529bead180e1569068

MULTIPLEX PCR FOR DETECTION OF NPM1 W288CFS AND FLT3-ITD MUTATIONS IN ACUTE MYELOID LEUKEMIA PATIENTS IN AMAZONAS STATES, BRAZIL

Autor: TCD Santos, LKG Sousa, GSP Braz, MOD Santos, MOD Nascimento, LA Cassa-Barbosa, LPS Mourão, AM Tarragô, GAV Silva

Publikováno v: Hematology, Transfusion and Cell Therapy, Vol 46, Iss , Pp S372-S373 (2024)

Introduction: Acute Myeloid Leukemia (AML) is a hematological disease clonal characterized by proliferation neoplasm cells in the bone marrow and peripheral blood, in consequence genetic alterations at hematopoietic stem cells. Genetic variants, as F

Externí odkaz: https://doaj.org/article/c4200edadd8e423fb2782475ee4e45f8

DETECÇÃO DE VARIANTES Y253H E E255K DO BCR::ABL1 EM PACIENTES COM LEUCEMIA MIELOIDE CRÔNICA NO ESTADO DO AMAZONAS

Autor: VC Costa, MOD Nascimento, MOD Santos, TCD Santos, GSP Braz, LPS Mourão, WO Azevedo, ROD Santos, AM Tarragô, GAV Silva

Publikováno v: Hematology, Transfusion and Cell Therapy, Vol 45, Iss , Pp S180- (2023)

Introdução: A Leucemia Mieloide Crônica (LMC) é uma doença hematológica classificada como Neoplasia Mieloproliferativa (NMP), caracterizada por transformação maligna e proliferação clonal de uma célula Troco Hematopoiética (HSC). A LMC é

Externí odkaz: https://doaj.org/article/9a340e65728d4de1bd8086ca502eec7b

P72R TP53 VARIANT AS A POTENTIAL MARKER FOR ACUTE MYELOID LEUKEMIA FROM AMAZONAS STATE, BRAZIL

Autor: GSP Braz, TCD Santos, MOD Santos, VC Costa, LPS Mourão, WO Azevedo, ROD Santos, AM Tarragô, GAV Silva

Publikováno v: Hematology, Transfusion and Cell Therapy, Vol 45, Iss , Pp S261-S262 (2023)

Background: Acute Myeloid Leukemia (AML) a cancer of the white blood cells, characterized by infiltration of leukemic blasts in the bone marrow (BM), affects the proliferation and maturation of the cells in the BM. Genetic variants are related in the

Externí odkaz: https://doaj.org/article/25ea1688c64f4d86b626f6578bfa36de

Abiotic Factors Modulating Metabolite Composition in Brown Algae (Phaeophyceae): Ecological Impacts and Opportunities for Bioprospecting of Bioactive Compounds.

Autor: Lopes C; Laboratory of Natural Products from Seaweeds (ALGAMAR), Department of Marine Biology, Institute of Biology, Federal Fluminense University, Niterói 24210-201, RJ, Brazil., Obando JMC; Laboratory of Natural Products from Seaweeds (ALGAMAR), Department of Marine Biology, Institute of Biology, Federal Fluminense University, Niterói 24210-201, RJ, Brazil.; Ideas Aquarium, Scientific and Technological Base Incubator of the Ribeira Valley and South Coast of São Paulo, São Paulo State University 'Júlio de Mesquita Filho', Registro 11900-000, SP, Brazil.; National Institute of Science and Technology in Nanotechnology for Sustainable Agriculture, INCTNanoAgro, Sorocaba 18087-180, SP, Brazil., Santos TCD; Laboratory of Natural Products from Seaweeds (ALGAMAR), Department of Marine Biology, Institute of Biology, Federal Fluminense University, Niterói 24210-201, RJ, Brazil.; Ideas Aquarium, Scientific and Technological Base Incubator of the Ribeira Valley and South Coast of São Paulo, São Paulo State University 'Júlio de Mesquita Filho', Registro 11900-000, SP, Brazil., Cavalcanti DN; Laboratory of Natural Products from Seaweeds (ALGAMAR), Department of Marine Biology, Institute of Biology, Federal Fluminense University, Niterói 24210-201, RJ, Brazil.; Postgraduate Program in Marine Biology and Coastal Ecosystems, Institute of Biology, Federal Fluminense University, Niterói 24210-201, RJ, Brazil., Teixeira VL; Laboratory of Natural Products from Seaweeds (ALGAMAR), Department of Marine Biology, Institute of Biology, Federal Fluminense University, Niterói 24210-201, RJ, Brazil.; Postgraduate Program in Neotropical Biodiversity, Institute of Biosciences, Federal University of the State of Rio de Janeiro, Rio de Janeiro 22290-240, RJ, Brazil.; Postgraduate Program in Science and Biotechnology, Institute of Biology, Federal Fluminense University, Niterói 24210-201, RJ, Brazil.

Publikováno v: Marine drugs [Mar Drugs] 2024 Dec 02; Vol. 22 (12). Date of Electronic Publication: 2024 Dec 02.