Výsledky vyhledávání - "TBAHS, tetrabutylammonium hydrogen sulfate"

Effects of antibiotic antitumor drugs on nucleotide levels in cultured tumor cells: an exploratory method to distinguish the mechanisms of antitumor drug action based on targeted metabolomics

Autor: Lixin Sun, Xi Liu, Zheng Liu, Cuichai Liu, Fang Wang

Publikováno v: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 5, Iss 3, Pp 223-230 (2015)

Nucleotide pools in mammalian cells change due to the influence of antitumor drugs, which may help in evaluating the drug effect and understanding the mechanism of drug action. In this study, an ion-pair RP-HPLC method was used for a simple, sensitiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e4570a8b7fa77c93ff61bd2d9a519b1
https://pubmed.ncbi.nlm.nih.gov/26579450

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Mitochondrial thiol modification by a targeted electrophile inhibits metabolism in breast adenocarcinoma cells by inhibiting enzyme activity and protein levels

Autor: Gloria A. Benavides, M. Ryan Smith, Sadanandan E. Velu, Hafez Golzarian, Praveen K. Vayalil, Bhavitavya Nijampatnam, Michael P. Murphy, Aimee Landar, Reena R. Beggs, Fen Zhou, Robin A.J. Smith, Patsy G. Oliver

Publikováno v: Redox Biology
Redox Biology, Vol 8, Iss C, Pp 136-148 (2016)

Many cancer cells follow an aberrant metabolic program to maintain energy for rapid cell proliferation. Metabolic reprogramming often involves the upregulation of glutaminolysis to generate reducing equivalents for the electron transport chain and am

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::418d05e427dd1077bf4931aef3f27b35

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Akademický článek

Effects of antibiotic antitumor drugs on nucleotide levels in cultured tumor cells: an exploratory method to distinguish the mechanisms of antitumor drug action based on targeted metabolomics.

Autor: Wang F; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China., Liu X; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China., Liu C; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China., Liu Z; School of Life Science and Bio-pharmaceutics Shenyang Pharmaceutical University, Shenyang 110016, China., Sun L; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.

Publikováno v: Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2015 May; Vol. 5 (3), pp. 223-30. Date of Electronic Publication: 2015 Apr 08.

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