Zobrazeno 1 - 10
of 297
pro vyhledávání: '"TAp73"'
Autor:
Hugo Alonso-Olivares, Margarita M. Marques, Anna Prieto-Colomina, Lorena López-Ferreras, Nicole Martínez-García, Alberto Vázquez-Jiménez, Victor Borrell, Maria C. Marin, Rosalia Fernandez-Alonso
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
IntroductionNeurogenesis is tightly regulated in space and time, ensuring the correct development and organization of the central nervous system. Critical regulators of brain development and morphogenesis in mice include two members of the p53 family
Externí odkaz:
https://doaj.org/article/a0f4649edac84157a5122025cfc2b2a7
Akademický článek
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Autor:
Xiangmudong Kong, Wensheng Yan, Wenqiang Sun, Yanhong Zhang, Hee Jung Yang, Mingyi Chen, Hongwu Chen, Ralph W de Vere White, Jin Zhang, Xinbin Chen
Publikováno v:
eLife, Vol 12 (2023)
TP73, a member of the p53 family, is expressed as TAp73 and ΔNp73 along with multiple C-terminal isoforms (α−η). ΔNp73 is primarily expressed in neuronal cells and necessary for neuronal development. Interestingly, while TAp73α is a tumor supp
Externí odkaz:
https://doaj.org/article/3d0f73f2102d4f66a7d02282d5fbfdc7
Autor:
Hong‐Juan Liu, Meng‐Yun Deng, Yan‐Yan Zhu, De‐Ling Wu, Xiao‐Hui Tong, Li Li, Lei Wang, Fei Xu, Tong‐Sheng Wang
Publikováno v:
Animal Models and Experimental Medicine, Vol 4, Iss 4, Pp 351-358 (2021)
Abstract Background Oligoasthenospermia is one of the main causes of male infertility. Researchers usually use chemical drugs to directly damage germ cells to prepare oligoasthenospermia models, which disregards the adhesion and migration between spe
Externí odkaz:
https://doaj.org/article/1318431857534817bf93d4201513adae
Autor:
Wenhu Li, Xianliao Zhang, Xinhua Xi, Yufa Li, Hong Quan, Shifeng Liu, Liqi Wu, Penghuan Wu, Wenxing Lan, Yongjun Shao, Haomiao Li, Kebing Chen, Zhengbo Hu
Publikováno v:
Cancer Medicine, Vol 9, Iss 12, Pp 4371-4385 (2020)
Abstract There are three subtypes of undifferentiated human conventional osteosarcoma (HCOS): osteoblastic osteosarcoma (OOS), chondroblastic osteosarcoma (COS), and fibroblastic osteosarcoma (FOS). HCOS also exhibits heterogeneous pathological maldi
Externí odkaz:
https://doaj.org/article/14630367e0b841329edd70c16713e629
Autor:
Brittany L. Bunch, Yingyu Ma, Kristopher Attwood, Lauren Amable, Wei Luo, Carl Morrison, Khurshid A. Guru, Anna Woloszynska‐Read, Pamela A. Hershberger, Donald L. Trump, Candace S. Johnson
Publikováno v:
Cancer Medicine, Vol 8, Iss 5, Pp 2449-2461 (2019)
Abstract Background Vitamin D3 (VitD) deficiency is linked to increased incidence and worse survival in bladder cancer (BCa). In addition to cystectomy, patients are treated with cisplatin‐based chemotherapy, however 30%‐50% of patients do not be
Externí odkaz:
https://doaj.org/article/22ca1c97f38345faa050654f631ae09d
Autor:
Marini, Alberto, Rotblat, Barak, Sbarrato, Thomas, Niklison-Chirou, Maria Victoria, Knight, John R. P., Dudek, Kate, Jones, Carolyn, Bushell, Martin, Knight, Richard A., Amelio, Ivano, Willis, Anne E., Melino, Gerry
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2018 Jun 01. 115(24), 6219-6224.
Externí odkaz:
https://www.jstor.org/stable/26510110
Autor:
Alicja Sznarkowska, Anna Kostecka, Anna Kawiak, Pilar Acedo, Mattia Lion, Alberto Inga, Joanna Zawacka-Pankau
Publikováno v:
Cell Division, Vol 13, Iss 1, Pp 1-12 (2018)
Abstract Background The p73 protein is a tumor suppressor that shares structural and functional similarity with p53. p73 is expressed in two major isoforms; the TA isoform that interacts with p53 pathway, thus acting as tumor suppressor and the N-ter
Externí odkaz:
https://doaj.org/article/2565f0ae0365422295256ca0f89c0535
Akademický článek
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Akademický článek
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