Zobrazeno 1 - 10
of 17 269
pro vyhledávání: '"TAU Protein"'
Publikováno v:
环境与职业医学, Vol 41, Iss 11, Pp 1270-1276 (2024)
BackgroundCyclic AMP response element binding protein (CREB) and miR-132-3p have been proved to be related to many neurodegenerative diseases. Our research group previously has demostrated that the neurotoxicity of aluminum is relevant to abnormal ph
Externí odkaz:
https://doaj.org/article/770a166a56bd419f8e697dce20a74aa3
Publikováno v:
Journal of Applied Pharmaceutical Research, Vol 12, Iss 5, Pp 1-15 (2024)
Background: Cognitive decline is developing as a critical alarm in public health concerns initiated by neuroinflammation, an indispensable contributing factor in neurodegenerative diseases. Probiotics and postbiotics have evolved as key therapeutic f
Externí odkaz:
https://doaj.org/article/8cf779eefaa14bd89d63b9e8629e936c
Publikováno v:
Exploration of Neuroprotective Therapy, Vol 4, Iss 5, Pp 401-410 (2024)
Alzheimer’s disease (AD) is the leading cause of dementia worldwide. The disease is characterized by the abnormal accumulation of amyloid β (Aβ) protein creating neuritic plaques, hyperphosphorylated tau (p-tau) protein forming intracellular tang
Externí odkaz:
https://doaj.org/article/2cb8f8113bc0467cbebea2f05de6f393
Autor:
Mohammad Arastoo, Lewis K. Penny, Richard Lofthouse, Aya Abdallah, Anna Abrahamsson, Pietro Marini, Valeria Melis, Gernot Riedel, Charles R. Harrington, Claude M. Wischik, Andrew Porter, Soumya Palliyil
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-20 (2024)
Abstract Background Recent advances in blood-based biomarker discovery are paving the way for simpler, more accessible diagnostic tools that can detect early signs of Alzheimer’s disease (AD). Recent successes in the development of amyloid-targetin
Externí odkaz:
https://doaj.org/article/3efb8c85249a4d3e81c8e65617f504f9
Publikováno v:
Muller Journal of Medical Sciences and Research, Vol 15, Iss 1, Pp 40-47 (2024)
Diabetes mellitus (DM) is a common endocrine disorder. It has an impact on various organs and systems in the body. Both hypo- and hyper-glycemia can lead to cognitive impairment through several metabolic pathways. Previously, the battery of studies h
Externí odkaz:
https://doaj.org/article/ff5067cd03fd4c0a935dff4ae41c3f52
Autor:
Mohammad Sadeghi, Ali Azargoonjahromi, Hamide Nasiri, Arash Yaghoobi, Maryam Sadeghi, Seyedeh Saeideh Chavoshi, Shilan Baghaeikia, Nastaran Mahzari, Arina Valipour, Romina Razeghi Oskouei, Farshad Shahkarami, Fatemeh Amiri, Mahsa Mayeli
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-11 (2024)
Abstract Mild Cognitive Impairment (MCI) is a neurological condition characterized by a noticeable decline in cognitive abilities that falls between normal aging and dementia. Along with some biomarkers like GAP-43, Aβ, tau, and P-tau, brain activit
Externí odkaz:
https://doaj.org/article/c34c32b9389b4ea69ac86b14062d046d
Autor:
E. M. Kondaurova, A. A. Komarova, T. V. Ilchibaeva, A. Ya. Rodnyy, E. A. Zalivina, V. S. Naumenko
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 28, Iss 4, Pp 398-406 (2024)
Serotonin 5-HT7 receptors (5-HT7R) are attracting increasing attention as important participants in the mechanisms of Alzheimer’s disease and as a possible target for the treatment of various tau pathologies. In this study, we investigated the effe
Externí odkaz:
https://doaj.org/article/795e06d363584def8d839011eb131950
Publikováno v:
Pharmacological Research - Modern Chinese Medicine, Vol 13, Iss , Pp 100543- (2024)
Introduction: Alzheimer's disease (AD) accounts for the majority of dementia cases, characterized by a gradual decline in memory and cognitive functions. Traditional Chinese medicine (TCM) has a long history of treating AD and has proposed a series o
Externí odkaz:
https://doaj.org/article/a0695163fbe741ba99334479a668b99d
Publikováno v:
Heliyon, Vol 10, Iss 20, Pp e39217- (2024)
Alzheimer's disease (AD) is a severe neurodegenerative disorder characterized by the accumulation of β-amyloid (Aβ) plaques and tau phosphorylation-induced neurofibrillary tangles. This review comprehensively summarizes AD pathogenesis and related
Externí odkaz:
https://doaj.org/article/fc7efd181b3f4dce861376b3ba715058