Zobrazeno 1 - 10
of 44
pro vyhledávání: '"TATSUTO KIYOSUE"'
Publikováno v:
British Journal of Pharmacology. 128:1733-1738
We investigated the effects of bepridil on the two components of the delayed rectifier K+ current, i.e., the rapidly activating (IKr) and the slowly activating (IKs) currents using tight-seal whole-cell patch-clamp techniques in guinea-pig ventricula
Autor:
Makoto Arita, Tatsuto Kiyosue
Publikováno v:
Cardiovascular Research. 44:13-16
See article by Yao et al. [2] (pages 132–145) in this issue. In animal models of myocardial infarction (MI), in which the coronary artery is occluded permanently, the incidence of ventricular arrhythmias is classified into three categories accordin
Publikováno v:
Journal of Cardiovascular Pharmacology. 33:492-499
We studied the effects of a new antiarrhythmic and antianginal agent, bepridil, on the intracellular calcium transient and contraction of cultured neonatal rat ventricular cells. and compared the effects with those caused by an authentic Ca 2+ -entry
Publikováno v:
Journal of Molecular and Cellular Cardiology. 31:533-542
The Na(+)-K+ pump is a consumer of intracellular ATP. We therefore examined whether blockade of the Na(+)-K+ pump by cardiac glycosides could inhibit ATP-sensitive K+ (KATP) channels and prolong the action potential duration (APD) of the guinea-pig v
Publikováno v:
Cardiovascular Drugs and Therapy. 13:105-113
Summary. In this study, we compared the effects of pimobenda (PIM), a putative Ca2+-sensitizer and phosphodiesterase (PDE) inhibitor, on the L-type Ca2+ current (ICa) of guinea-pig ventricular myocytes and contractile tension of ventricular papillary
Publikováno v:
Japanese Journal of Electrocardiology. 17:329-334
パッチ電極を用いた細胞全膜電位固定法にて, ストレプトゾトシン誘発慢性糖尿病ラット心室筋細胞のイオン電流を正常ラットのそれと比較した.慢性糖尿病群の心室筋細胞では, 正常群
Publikováno v:
Japanese Circulation Journal. 58:1219-1224
Publikováno v:
Japanese Journal of Electrocardiology. 14:24-31
機械的伸展に伴う心筋細胞内Ca2+動態の変化を解析し, そのメカニズムについて考察した.新生児ラットの心室筋細胞を無蛍光シリコンラバーに培養し, このラバーを手動マニピュレータで
Publikováno v:
Cardiovascular Drugs and Therapy. 7:575-584
We investigated the effect of lysophosphatidylcholine (lysoPtdCho) and palmitoylcarnitine (PamCar), ischemia-induced amphipathic lipid metabolites, on the inward rectifier K+ channel in guinea-pig ventricular cells, under whole-cell and cell-attached
Publikováno v:
Japanese Journal of Electrocardiology. 13:3-9
各種抗不整脈薬のATP感受性K+チャネルに対する効果をモルモット心室筋細胞を用いて検討した.ランプ波膜電位固定により得られる疑似定常状態膜電流に代謝阻害剤2, 4-dinitrophenol (50μM) を